The carcinogenic action of crystalline silica: A review of the evidence supporting secondary inflammation-driven genotoxicity as a principal mechanism

Critical Reviews in Toxicology

Volumn 41, Issue 9, 2011, Pages 756-770

  Borm, Paul J A ^a   Tran, Lang ^b   Donaldson, Ken ^c  

^a ZUYD UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

^b Insititue of Occupational Medicine   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Carcinogenicity; Genotoxicity; Inflammation; Occupational; Review; Silica; Surface

Indexed keywords

CARCINOGEN; SILICON DIOXIDE;

CANCER RESEARCH; CARCINOGENICITY; GENOTOXICITY; INFLAMMATION; LUNG TUMOR; MACROPHAGE ACTIVATION; REVIEW;

ANIMALS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INFLAMMATION; MUTAGENICITY TESTS; OCCUPATIONAL EXPOSURE; QUARTZ; RATS; SILICON DIOXIDE;

ANIMALIA; RATTUS;

EID: 80052953528     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408444.2011.576008     Document Type: Review

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