Cytotoxicity and genotoxicity of ultrafine crystalline SiO2 participate in cultured human lymphoblastoid cells

Environmental and Molecular Mutagenesis

Volumn 48, Issue 2, 2007, Pages 151-157

  Wang, Jing J ^a   Sanderson, Barbara J S ^b   Wang, He ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

DNA damage; HPRT mutation; Micronucleus; Silica; Ultrafine particles

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; SILICON DIOXIDE; TETRAZOLIUM;

ARTICLE; BIOASSAY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINESIS; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MICRONUCLEUS TEST; PARTICULATE MATTER;

APOPTOSIS; CELL SURVIVAL; DNA DAMAGE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENICITY TESTS; MUTAGENS; SILICON DIOXIDE; SILICONES; TUMOR CELLS, CULTURED;

EID: 33847660189     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20287     Document Type: Article

References (34)

1. Basaran N, Shubair M, Undeger U, Kars A. 2003. Monitoring of DNA damage in foundry and pottery workers exposed to silica by the alkaline comet assay. Am J Ind Med 43:602-610.
2. Bill CA, Yu Y. Miselis NR, Little JB, Nickoloff JA. 1997. A role for p53 in DNA end rejoining by human cell extracts. Mutat Res 385:21-29.
3. Driscoll KE, Deyo LC, Carter JM, Howard BW, Hassenbein DG, Bertram TA. 1997. Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells. Carcinogenesis 18:423-430.
4. Fenech M. 2000. The in vitro micronucleus technique. Mutat Res 455:81-95.
5. Frampton MW. 2001. Systemic and cardiovascular effects of airway injury and inflammation: Ultrafine particle exposure in humans. Environ Health Perspect 109 (Suppl 4):529-532.
6. Freshney RI. 2000. Culture of Animal Cells: A Manual of Basic Technique. New York: Wiley-Liss. pp 330-332.
7. Fubini B, Hubbard A. 2003. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34:1507-1516.
8. He JL, Chen WL, Jin LF, Jin HY. 2000. Comparative evaluation of the in vitro micronucleus test and the comet assay for the detection of genotoxic effects of X-ray radiation. Mutat Res 469:223-231.
9. Heddle JA, Hite M, Kirkhart B, Mavournin K, MacGregor JT, Newell GW, Salamone MF. 1983. The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res 123:61-118.
10. Ishihara Y, Iijima H, Matsunaga K, Fukushima T, Nishikawa T, Takenoshita S. 2002. Expression and mutation of p53 gene in the lung of mice intratracheal injected with crystalline silica. Cancer Lett 177:125-128.
11. Iyer R, Hamilton RF, Li L, Holian A. 1996. Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages Toxicol Appl Pharmacol 141:84-92.
12. Johnston CJ, Driscoll KE, Finkelstein JN, Baggs R, O'Reilly MA, Carter J, Gelein R, Oberdorster G. 2000. Pulmonary chemokine and mutagenic responses in rats after subchronic inhalation of amorphous and crystalline silica. Toxicol Sci 56:405-413.
13. Kirsch-Volders M, Elhajoui A, Cundari E, van Hummelen P. 1997. The in vitro micronucleous test: A multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat Res 392:19-30.
14. Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate M Jr, Kirchner S, Lorge E, Morita T, Norppa H, Surralles J, Vanhauwaert A, Wakata A. 2004. Corrigendum to "Report from the in vitro micronucleus assay working group" [Mutat Res 2003; 540:153-163.]. Mutat Res 564:97-100 (Erratum).
15. Leigh J, Bonin A, Wang H. 2000. In vivo genotoxicity of crystalline silica as evidenced by micronuclei in pulmonary alveolar macrophages: Low-dose study. Inhal Toxicol 12:199-204.
16. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. 2003. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect 111:455-460.
17. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
18. Nagalakshmi R, Nath J, Ong T, Whong WZ. 1995. Silica-induced micronuclei and chromosomal aberrations in Chinese hamster lung (V79) and human lung (Hel 299) cells. Mutat Res 335:27-33.
19. Nemmar A, Hoet PH, Vanquickenborne B, Dinsdale D, Thomeer M, Hoylaerts MF, Vanbilloen H, Mortelmans L, Nemery B. 2002. Passage of inhaled particles into the blood circulation in humans. Circulation 105:411-414.
20. Oberdorster G. 1996. Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles Inhal Toxicol 8:73-89.
21. OECD. 2004. OECD guideline for the testing of chemicals draft proposal for a new guideline 487: In vitro micronucleus test. Paris: OECD. Available at http://www.oecd.org/dataoecd/60/28/32/06288.pdf.
22. Sanderson BJS, Johnson KJ, Henner WD. 1991. Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells. Environ Mol Mutagen 17:238-243.
23. Santarelli L, Recchioni R, Moroni F, Marcheselli F, Governa M. 2004. Crystalline silica induces apoptosis in human endothelial cells in vitro. Cell Biol Toxicol 20:97-108.
24. Shield AJ, Sanderson BJS. 2004. A recombinant model for assessing the role of GSTMI in styrene-7,8-oxide toxicity and mutagenicity. Toxicology 195:61-68.
25. Surralles J, Xamena N, Creus A, Catalan J, Norppa H, Marcos R. 1995. Induction of micronuclei by five pyrethroid insecticides in whole-blood and isolated human lymphocyte cultures. Mutat Res 341:169-184.
26. Tafazoli M, Kirsch-Volders M. 1996. In vitro mutagenicity and genotoxicity study of 1,2-dichloroethylene, 1,1,2-trichloroethane, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropene, using the micronucleus test and the alkaline single cell gel electrophoresis technique (comet assay) in human lymphocytes. Mutat Res 371:185-202.
27. Umegaki K, Fenech M. 2000. Cytokinesis-block micronucleus assay in WIL2-NS cells: A sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagen 15:261-269.
28. van Duuren BL, Nelson N, Orris L, Palmes ED, Schmitt FL. 1963. Carcinogenicity of epoxides, lactones and peroxy compounds. J Natl Cancer Inst 31:41-55.
29. van Goethem F, Lison D, Kirsch-Volders M. 1997. Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: Genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat Res 392:31-43.
30. Vanchugova NN, Frash VN, Kogan FM. 1985. Use of the micronucleus test as a rapid method of detecting the potential carcinogenicity of asbestos-containing and other mineral fibers. Gig Tr Prof Zabol 45-48.
31. Wang L, Bowman L, Lu Y, Rojanasakul Y, Mercer RR, Castranova V, Ding M. 2005. Essential role of p53 in silica-induced apoptosis. Am J Physiol Lung Cell Mol Physiol 288:L488-L496.
32. Wu J, Gu L, Wang H, Geacintov NE, Li GM. 1999. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis. Mol Cell Biol 19:8292-8301.
33. Xia F, Wang X, Wang YH, Tsang NM, Yandell DW, Kelsey KT, Liber HL. 1995. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res 55:12-15.
34. Young FM, Phungtamdet W, Sanderson BJ. 2005. Modification of MTT assay conditions to examine the cytotoxic effects of amitraz on the human lymphoblastoid cell line, WIL2NS. Toxicol In Vitro 19:1051-1059.