Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 2, 2006, Pages

  Ding, Min ^a   Huang, Chuanshu ^b   Lu, Yongju ^a   Bowman, Linda ^a   Castranova, Vince ^a   Vallyathan, Val ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activator protein 1; Mitogen activated protein kinase; Protein kinase C; Silica

Indexed keywords

3 [8 [(DIMETHYLAMINO)METHYL] 6,7,8,9 TETRAHYDROPYRIDO[1,2 A]INDOL 10 YL] 4 (1 METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; BISINDOLYLMALEIMIDE; CALPHOSTIN C; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; SILICON DIOXIDE; TRANSCRIPTION FACTOR AP 1; BISINDOLYLMALEIMIDE I; ENZYME INHIBITOR; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; NAPHTHALENE DERIVATIVE; PYRROLE DERIVATIVE; RO 32-0432;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; CYTOSOL; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPIDERMIS CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; CELL LINE; CRYSTALLIZATION; ENZYME ACTIVATION; ENZYME INHIBITORS; INDOLES; MALEIMIDES; MAP KINASE SIGNALING SYSTEM; MICE; NAPHTHALENES; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-EPSILON; PROTEIN TRANSPORT; PYRROLES; SILICON DIOXIDE; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 33644841444     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00053.2005     Document Type: Article

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