Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4676-4681

  Silva, Daniel ^a,b   Chioua, Mourad ^b   Samadi, Abdelouahid ^b   Carmo Carreiras, M ^a   Jimeno, María Luisa ^c   Mendes, Eduarda ^a   Ríos, Cristóbal De Los ^d,e   Romero, Alejandro ^f,h   Villarroya, Mercedes ^d,f   López, Manuela G ^f,g   Marco Contelles, José ^b  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^c CSIC Centro de Quimica Organica Lora Tamayo CENQUIOR   (Spain)

^d HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^e UNIVERSITY OF ALCALÁ   (Spain)

^f INSTITUTO TEÓFILO HERNANDO   (Spain)

^g HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

^h UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

AChE BuChE inhibitors; Alzheimer's disease; Neuroprotection; Oxidative stress; Pyrazolotacrines

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; HETEROCYCLIC COMPOUND; NAPHTHYRIDINE DERIVATIVE; NIMODIPINE; OLIGOMYCIN; QUINOLINE DERIVATIVE; ROTENONE; TACRINE;

ARTICLE; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHORUS; HORSE; IC 50; NEUROPROTECTION;

ANIMALS; CHOLINESTERASE INHIBITORS; HORSES; INHIBITORY CONCENTRATION 50; PYRAZOLES;

EID: 80052951494     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.05.068     Document Type: Article

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