Potent acetylcholinesterase inhibitors: Design, synthesis, and structure - Activity relationships of bis-interacting ligands in the galanthamine series

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 10, 1998, Pages 1835-1850

  Mary, Aude ^a   Renko, Dolor Zafiarisoa ^a   Guillou, Catherine ^a   Thal, Claude ^a  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; LIGAND BINDING; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; BENZAZEPINES; BINDING SITES; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; DRUG DESIGN; GALANTAMINE; PHTHALIMIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031726513     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00133-3     Document Type: Article

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21. Compound 14 was prepared as described in reference 6. (matrix presented)