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Volumn 41, Issue 12, 2006, Pages 1464-1469
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Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals
a
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Author keywords
AChE; Alzheimer's disease; BuChE; Inhibitors; Multipotent drugs; Neuroprotection; Pyrano 2,3 b quinolines; Tacrine; Voltage dependent calcium channels (VDCC)
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Indexed keywords
CHOLINESTERASE INHIBITOR;
DONEPEZIL;
ETHYL 5 AMINO 4 (2 BROMO 3 PYRIDYL) 2 METHYL 6,7,8,9 TETRAHYDRO 4H PYRANO[2,3 BETA]QUINOLINE 3 CARBOXYLATE;
ETHYL 5 AMINO 4 (2 CHLORO 3 PYRIDYL)2 METHYL 6,7,8,9 TETRAHYDRO 4H PYRANO[2,3 BETA]QUINOLINE 3 CARBOXYLATE;
ETHYL 5 AMINO 4 (2 METHOXY 3 PYRIDYL) 2 METHYL 6,7,8,9 TETRAHYDRO 4H PYRANO[2,3 BETA]QUINOLINE 3 CARBOXYLATE;
FREE RADICAL;
NIMODIPINE;
QUINOLINE DERIVATIVE;
TACRINE;
ANIMAL CELL;
ARTICLE;
CONTROLLED STUDY;
DRUG MECHANISM;
DRUG POTENCY;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
NERVE CELL NECROSIS;
NEUROPROTECTION;
NONHUMAN;
ADRENAL MEDULLA;
ANIMALS;
CALCIUM;
CALCIUM SIGNALING;
CATTLE;
CELL LINE;
CHOLINESTERASE INHIBITORS;
CHROMAFFIN CELLS;
DRUG EVALUATION, PRECLINICAL;
FREE RADICALS;
L-LACTATE DEHYDROGENASE;
MAGNETIC RESONANCE SPECTROSCOPY;
MASS SPECTROMETRY;
NEUROPROTECTIVE AGENTS;
PYRANS;
QUINOLINES;
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EID: 33845327840
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2006.06.016 Document Type: Article |
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Times cited : (51)
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References (14)
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