Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4252-4257

  El Kazzouli, Saïd ^a,b   Griffon Du Bellay, Amaury ^a   Berteina Raboin, Sabine ^a   Delagrange, Philippe ^c   Caignard, Daniel Henry ^c   Guillaumet, Gérald ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b MAScIR Foundation   (Morocco)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Imidazo 1,2 a pyridines; Melatonin receptor ligands; MT1, MT2 receptor subtypes

Indexed keywords

1 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL) N,N,N TRIMETHYL METHANAMINIUM IODIDE; 2 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ETHANAMINE; 2 PHENYLIMIDAZO[1,2 A]PYRIDINE DERIVATIVE; 3 (2 AZIDOETHYL) 6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDINE; 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL) N METHYLPROPANAMIDE; 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ETHANOL; 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)PROPANOIC ACID; 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDINE 3 YL) N METHYL PROPIONAMIDE; 3 (N,N DIMETHYLAMINOMETHYL) 6 METHYL 2 PHENYLIMIDAZO[1,2 A]PYRIDINE; 3 [2 ACETAMIDO 2 ETHOXYCARBONYLETHYL] 6 METHOXY 2 PHENYLIMIDAZOIMIDAZO[1,2 A]PYRIDINE; 3 [2 ACETAMIDO 2,2 BIS (ETHOXYCARBONYL)ETHYL] 6 METHOXY 2 PHENYLIMIDAZOIMIDAZO[1,2 A]PYRIDINE; 3 [2 ACETAMIDO 3 HYDROXYPROPYL] 6 METHOXY 2 PHENYLIMIDAZOIMIDAZO[1,2 A]PYRIDINE; 3 IODO 6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDINE; 6 BROMO 2 PHENYLIMIDAZO[1,2 A]PYRIDINE; 6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDINE; ETHYL 2 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ACETATE; LIGAND; MELATONIN RECEPTOR; METHYL 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ACRYLATE; METHYL 3 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)PROPANOATE; N (1 HYDROXY 3 (5 METHOXY 2 PHENYL 1H INDOL 3 YL)PROPAN 2 YL)ACETAMIDE; N [2 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDIN 3 YL)ETHYL]ACETAMIDE; N [2 (6 METHOXY 2 PHENYLIMIDAZO[1,2 A]PYRIDINE 3 YL)ETHYL]ACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CHO CELL; CONTROLLED STUDY; DRUG DESIGN; DRUG SELECTIVITY; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; PYRIDINES; RECEPTORS, MELATONIN; SPECTROPHOTOMETRY, INFRARED;

EID: 80052922538     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.06.030     Document Type: Article

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