Cellular model of Warburg Effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Ayyasamy, Vanniarajan ^a   Owens, Kjerstin M ^a   Desouki, Mohamed Mokhtar ^b   Liang, Ping ^c   Bakin, Andrei ^a   Thangaraj, Kumarasamy ^d   Buchsbaum, Donald J ^e   LoBuglio, Albert F ^f   Singh, Keshav K ^a,f  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c BROCK UNIVERSITY   (Canada)

^d CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^e The University of Alabama at Birmingham   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENIPIN; MITOCHONDRIAL DNA; PROTEIN; PROTEOME; REACTIVE OXYGEN METABOLITE; SMAD4 PROTEIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3; UNCOUPLING PROTEIN 4; UNCOUPLING PROTEIN 5; ADENOSINE TRIPHOSPHATE; ION CHANNEL; IRIDOID; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER TUMOR; BREAST CANCER; BREAST EPITHELIUM; BREAST TUMOR; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL INVASION; CELL LINE; CELL MIGRATION; CELL STRAIN MCF 7; COLORECTAL TUMOR; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EPITHELIUM CELL; ESOPHAGUS TUMOR; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY TUMOR; LEUKEMIA; LUNG TUMOR; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OVARY TUMOR; OXIDATIVE PHOSPHORYLATION; PANCREAS TUMOR; PRIMARY TUMOR; PROSTATE TUMOR; PROTEIN EXPRESSION; PROTEIN FUNCTION; TESTIS TUMOR; TUMOR PROMOTION; WARBURG EFFECT; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; TUMOR CELL LINE; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; ION CHANNELS; IRIDOID GLYCOSIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL PROTEINS; REACTIVE OXYGEN SPECIES; SMAD4 PROTEIN;

EID: 80052848190     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024792     Document Type: Article

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