Gene-specific transcription activation via long-range allosteric shape-shifting

Biochemical Journal

Volumn 439, Issue 1, 2011, Pages 15-25

  Tsai, Chung Jung ^a   Nussinov, Ruth ^a,b  

^a SAIC FREDERICK INC   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Allosteric pathway; Allosteric propagation; Allostery; Enhancer; Mediator; Transcription initiation; Transcription regulation; Transcription start site

Indexed keywords

MEDIATOR COMPLEX; RNA POLYMERASE II;

ALLOSTERISM; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CORRELATION ANALYSIS; GENETIC DISORDER; GENETIC TRANSCRIPTION; HUMAN; HYPOTHESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; REGULATORY SEQUENCE; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; HUMANS; MEDIATOR COMPLEX; RNA POLYMERASE II; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTIONAL ACTIVATION;

EID: 80052751115     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110972     Document Type: Review

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