메뉴 건너뛰기




Volumn 45, Issue 10, 2011, Pages 1232-1240

Lysosomal membrane permeabilization contributes to elemene emulsion-induced apoptosis in A549 cells

Author keywords

Apoptosis; Elemene; Lysosome; Oxidative stress

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CATHEPSIN D; ELEMENE; GLUTATHIONE; PEPSTATIN; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 80052719084     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.607818     Document Type: Article
Times cited : (11)

References (59)
  • 2
    • 0037216616 scopus 로고    scopus 로고
    • Classification, staging and prognosis of lung cancer
    • DOI 10.1016/S0720-048X(02)00287-5, PII S0720048X02002875
    • Beadsmoore CJ, Screaton NJ. Classifi cation, staging and prognosis of lung cancer. Eur J Radiol 2003;45:8-17. (Pubitemid 36024163)
    • (2003) European Journal of Radiology , vol.45 , Issue.1 , pp. 8-17
    • Beadsmoore, C.J.1    Screaton, N.J.2
  • 3
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
    • DOI 10.4065/83.5.584
    • Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Nonsmall cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008;83:584-594. (Pubitemid 351720831)
    • (2008) Mayo Clinic Proceedings , vol.83 , Issue.5 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 4
    • 0034799139 scopus 로고    scopus 로고
    • A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
    • Ciardiello F, Tortora G. A novel approach in the treatment of cancer. targeting the epidermal growth factor receptor. Clin Cancer Res 2001;7:2958-2970. (Pubitemid 32963812)
    • (2001) Clinical Cancer Research , vol.7 , Issue.10 , pp. 2958-2970
    • Ciardiello, F.1    Tortora, G.2
  • 5
    • 67449158739 scopus 로고    scopus 로고
    • Water extract of Rheum offi cinale Baill induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines
    • Li WY, Chan SW, Guo DJ, Chung MK, Leung TY, Yu PH. Water extract of Rheum offi cinale Baill induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. J Ethnopharmacol 2009;124:251-256.
    • (2009) J Ethnopharmacol , vol.124 , pp. 251-256
    • Li, W.Y.1    Chan, S.W.2    Guo, D.J.3    Chung, M.K.4    Leung, T.Y.5    Yu, P.H.6
  • 6
    • 0020756303 scopus 로고
    • Isolation and identifi cation of elemene from the essential oil of Curcuma wenyujin
    • Guo YT. Isolation and identifi cation of elemene from the essential oil of Curcuma wenyujin, Zhong Yao Tong Bao 1983;8:31-34.
    • (1983) Zhong Yao Tong Bao , vol.8 , pp. 31-34
    • Guo, Y.T.1
  • 7
    • 42649116109 scopus 로고    scopus 로고
    • Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK activation
    • DOI 10.1016/j.canlet.2008.01.049, PII S0304383508000748
    • Yao YQ, Ding X, Jia YC, Huang CX, Wang YZ, Xu YH. Antitumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation. Cancer Lett 2008;264:127-134. (Pubitemid 351602131)
    • (2008) Cancer Letters , vol.264 , Issue.1 , pp. 127-134
    • Yao, Y.-Q.1    Ding, X.2    Jia, Y.-C.3    Huang, C.-X.4    Wang, Y.-Z.5    Xu, Y.-H.6
  • 8
    • 78651228470 scopus 로고    scopus 로고
    • ß-Elemene inhibits proliferation of human glioblastoma cells and causes cell-cycle G0/G1 arrest via mutually compensatory activation of MKK3 and MKK6
    • Zhu T, Zhao Y, Zhang J, Li L, Zou L, Yao Y, Xu Y. ß-Elemene inhibits proliferation of human glioblastoma cells and causes cell-cycle G0/G1 arrest via mutually compensatory activation of MKK3 and MKK6. Int J Oncol 2011;38(2):419-426.
    • (2011) Int J Oncol , vol.38 , Issue.2 , pp. 419-426
    • Zhu, T.1    Zhao, Y.2    Zhang, J.3    Li, L.4    Zou, L.5    Yao, Y.6    Xu, Y.7
  • 9
    • 0032971783 scopus 로고    scopus 로고
    • Elemene induces apoptosis and regulates expression of bcl-2 protein in human leukemia K562 cells
    • Yuan J, Gu ZL, Chou WH, Kwok CY. Elemene induces apoptosis and regulates expression of bcl-2 protein in human leukemia K562 cells. Zhongguo Yao Li Xue Bao 1999;20: 103-106. (Pubitemid 29084940)
    • (1999) Acta Pharmacologica Sinica , vol.20 , Issue.2 , pp. 103-106
    • Yuan, J.1    Gu, Z.-L.2    Chou, W.-H.3    Kwok, C.-Y.4
  • 10
    • 0029948629 scopus 로고    scopus 로고
    • The antitumor activity of elemene is associated with apoptosis
    • Yang H, Wang X, Yu L. The antitumor activity of elemene is associated with apoptosis. Zhonghua Zhong Liu Za Zhi 1996; 18:169-172. (Pubitemid 26188024)
    • (1996) Chinese Journal of Oncology , vol.18 , Issue.3 , pp. 169-172
    • Yang, H.1    Wang, X.2    Yu, L.3
  • 11
    • 0035352830 scopus 로고    scopus 로고
    • Beta-elemene induces apoptosis of K562 leukemia cells
    • Zou L, Liu W, Yu L. beta-elemene induces apoptosis of K562 leukemia cells. Zhonghua Zhong Liu Za Zhi 2001;23: 196-198.
    • (2001) Zhonghua Zhong Liu Za Zhi , vol.23 , pp. 196-198
    • Zou, L.1    Liu, W.2    Yu, L.3
  • 12
    • 33645990875 scopus 로고    scopus 로고
    • Elemene displays anti-c ancer ability on laryngeal cancer cells in vitro and in vivo
    • Tao L, Zhou L, Zheng L, Yao M. Elemene displays anti-c ancer ability on laryngeal cancer cells in vitro and in vivo. Cancer Chemother Pharmacol 2006;58:24-34.
    • (2006) Cancer Chemother Pharmacol , vol.58 , pp. 24-34
    • Tao, L.1    Zhou, L.2    Zheng, L.3    Yao, M.4
  • 13
    • 18544381215 scopus 로고    scopus 로고
    • Antiproliferative effect of β-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase
    • DOI 10.1007/s00018-005-5027-1
    • Li X, Wang G, Zhao J, Ding H, Cunningham C, Chen F, et al. Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase. Cell Mol. Life Sci. 2005;62:894-904. (Pubitemid 40655636)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.7-8 , pp. 894-904
    • Li, X.1    Wang, G.2    Zhao, J.3    Ding, H.4    Cunningham, C.5    Chen, F.6    Flynn, D.C.7    Reed, E.8    Li, Q.Q.9
  • 14
    • 16644375041 scopus 로고    scopus 로고
    • Reversal of resistance to adriamycin in human breast cancer cell line MCF-7/ADM by beta-elemene
    • Hu J, Jin W, Yang PM. Reversal of resistance to adriamycin in human breast cancer cell line MCF-7/ADM by beta-elemene. Zhonghua Zhong Liu Za Zhi 2004;26:268-270.
    • (2004) Zhonghua Zhong Liu Za Zhi , vol.26 , pp. 268-270
    • Hu, J.1    Jin, W.2    Yang, P.M.3
  • 16
    • 35148900318 scopus 로고    scopus 로고
    • In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma
    • Zhao J, Li QQ, Zou B, Wang G, Li X, Kim JE, et al. In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma. Int J Oncol 2007;31:241-252.
    • (2007) Int J Oncol , vol.31 , pp. 241-252
    • Zhao, J.1    Li, Q.Q.2    Zou, B.3    Wang, G.4    Li, X.5    Kim, J.E.6
  • 17
    • 68249162541 scopus 로고    scopus 로고
    • Beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis
    • Li QQ, Wang G, Zhang M, Cuff CF, Huang L, Reed E. beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis. Oncol Rep 2009;22:161-170.
    • (2009) Oncol Rep , vol.22 , pp. 161-170
    • Li, Q.Q.1    Wang, G.2    Zhang, M.3    Cuff, C.F.4    Huang, L.5    Reed, E.6
  • 18
    • 39449093070 scopus 로고    scopus 로고
    • Caspase activation cascades in apoptosis
    • DOI 10.1042/BST0360001
    • Logue SE, Martin SJ. Caspase activation cascades in apoptosis. Biochem Soc Trans 2008;36:1-9. (Pubitemid 351269611)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.1 , pp. 1-9
    • Logue, S.E.1    Martin, S.J.2
  • 19
    • 43949108922 scopus 로고    scopus 로고
    • The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity
    • DOI 10.1002/hep.22183
    • Li Z, Berk M, McIntyre TM, Gores GJ, Feldstein AE. The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity. Hepatology 2008;47:1495-1503. (Pubitemid 351702733)
    • (2008) Hepatology , vol.47 , Issue.5 , pp. 1495-1503
    • Li, Z.1    Berk, M.2    McIntyre, T.M.3    Gores, G.J.4    Feldstein, A.E.5
  • 20
    • 62949128915 scopus 로고    scopus 로고
    • Lysosomal involvement in cell death and cancer
    • Kirkegaard T, Jä ä t tel ä M. Lysosomal involvement in cell death and cancer. Biochim Biophys Acta 2009;1793:746-754.
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 746-754
    • Kirkegaard, T.1    Jäättelä, M.2
  • 21
    • 0035877037 scopus 로고    scopus 로고
    • 2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis
    • DOI 10.1016/S0891-5849(01)00526-3, PII S0891584901005263
    • Dar é E, Li W, Zhivotovsky B, Yuan X, Ceccatelli S. Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis. Free Radic Biol Med 2001;30:1347-1356. (Pubitemid 32522949)
    • (2001) Free Radical Biology and Medicine , vol.30 , Issue.12 , pp. 1347-1356
    • Dare, E.1    Li, W.2    Zhivotovsky, B.3    Yuan, X.4    Ceccatelli, S.5
  • 22
    • 33747329092 scopus 로고    scopus 로고
    • Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects
    • DOI 10.1016/j.freeradbiomed.2006.05.032, PII S0891584906003625
    • Larsson DA, Baird S, Nyhalah JD, Yuan XM, Li W. Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects. Free Radic Biol Med 2006;41: 902-910. (Pubitemid 44247546)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.6 , pp. 902-910
    • Larsson, D.A.1    Baird, S.2    Nyhalah, J.D.3    Yuan, X.-M.4    Li, W.5
  • 24
    • 0027352181 scopus 로고
    • H 2 O 2-mediated damage to lysosomal membranes of J-774 cells
    • Zdolsek J, Zhang H, Roberg K, Brunk U. H 2 O 2-mediated damage to lysosomal membranes of J-774 cells. Free Radic Res Commun 1993;18:71-85.
    • (1993) Free Radic Res Commun , vol.18 , pp. 71-85
    • Zdolsek, J.1    Zhang, H.2    Roberg, K.3    Brunk, U.4
  • 26
    • 0032988381 scopus 로고    scopus 로고
    • Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak
    • Brunk UT, Svensson I. Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak. Redox Rep 1999;4:3-11. (Pubitemid 29296774)
    • (1999) Redox Report , vol.4 , Issue.1-2 , pp. 3-11
    • Brunk, U.T.1    Svensson, I.2
  • 28
    • 0242266944 scopus 로고    scopus 로고
    • Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes
    • DOI 10.1016/S0887-2333(03)00123-1
    • Pourahmad J, O'Brien PJ, Jokar F, Daraei B. Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes. Toxicol In Vitro 2003;17:803-810. (Pubitemid 37352697)
    • (2003) Toxicology in Vitro , vol.17 , Issue.5-6 , pp. 803-810
    • Pourahmad, J.1    O'Brien, P.J.2    Jokar, F.3    Daraei, B.4
  • 29
    • 0030968310 scopus 로고    scopus 로고
    • Microgel electrophoresis: Sensitivity, mechanisms, and DNA electrostretching
    • DOI 10.1016/S0921-8777(96)00056-0, PII S0921877796000560
    • Singh NP, Stephens RE. Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching. Mutat Res 1997; 383:167-175. (Pubitemid 27117568)
    • (1997) Mutation Research - DNA Repair , vol.383 , Issue.2 , pp. 167-175
    • Singh, N.P.1    Stephens, R.E.2
  • 30
    • 21144458092 scopus 로고    scopus 로고
    • Protective effects of panduratin A against oxidative damage of tert-butylhydroperoxide in human HepG2 cells
    • DOI 10.1248/bpb.28.1083
    • Sohn JH, Han KL, Lee SH, Hwang JK. Protective effects of panduratin A against oxidative damage of tert-butylhydroperoxide in human HepG2 cells. Biol Pharm Bull 2005;28:1083-1086. (Pubitemid 40880320)
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , Issue.6 , pp. 1083-1086
    • Sohn, J.H.1    Han, K.-L.2    Lee, S.-H.3    Hwang, J.-K.4
  • 31
    • 0026554428 scopus 로고
    • Evaluation of the probe 2 ′,7 ′-dichlorofl uorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel CP, Ischiropoulos H, Bondy SC. Evaluation of the probe 2 ′,7 ′-dichlorofl uorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 1992;5:227-231.
    • (1992) Chem Res Toxicol , vol.5 , pp. 227-231
    • Lebel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 32
    • 0017064979 scopus 로고
    • A fl uorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin PJ, Hilf R. A fl uorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 1976;74:214-226.
    • (1976) Anal Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 34
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • DOI 10.1038/nrc1738
    • Kroemer G, Jä ä t tel ä M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005;5:886-897. (Pubitemid 41746033)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 35
    • 0031775463 scopus 로고    scopus 로고
    • Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy
    • Calkins CC, Sameni M, Koblinski J, Sloane BF, Moin K. Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy. J Histochem Cytochem 1998;46:745-751. (Pubitemid 28272209)
    • (1998) Journal of Histochemistry and Cytochemistry , vol.46 , Issue.6 , pp. 745-751
    • Calkins, C.C.1    Sameni, M.2    Koblinski, J.3    Sloane, B.F.4    Moin, K.5
  • 36
    • 77949270765 scopus 로고    scopus 로고
    • S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
    • G havami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayko AJ, et al. S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res 2010;20:314-331.
    • (2010) Cell Res , vol.20 , pp. 314-331
    • Ghavami, S.1    Eshragi, M.2    Ande, S.R.3    Chazin, W.J.4    Klonisch, T.5    Halayko, A.J.6
  • 37
    • 0035947776 scopus 로고    scopus 로고
    • Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
    • Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, et al. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001;153:999-1010.
    • (2001) J Cell Biol , vol.153 , pp. 999-1010
    • Foghsgaard, L.1    Wissing, D.2    Mauch, D.3    Lademann, U.4    Bastholm, L.5    Boes, M.6
  • 38
    • 0035408169 scopus 로고    scopus 로고
    • The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress
    • Kå g edal K, Johansson U, Ollinger K. The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress. FASEB J 2001;15:1592-1594.
    • (2001) FASEB J , vol.15 , pp. 1592-1594
    • Kågedal, K.1    Johansson, U.2    Ollinger, K.3
  • 39
    • 0036660887 scopus 로고    scopus 로고
    • Endosomal-lysosomal proteolysis mediates death signalling by TNFα, not by etoposide, in L929 fibrosarcoma cells: Evidence for an active role of cathepsin D
    • DOI 10.1515/BC.2002.137
    • D é moz M, Castino R, Cesaro P, Baccino FM, Bonelli G, Isidoro C. Endosomal-lysosomal proteolysis mediates death signalling by TNFalpha, not by etoposide, in L929 fi brosarcoma cells: evidence for an active role of cathepsin D. Biol Chem 2002;383:1237-1248. (Pubitemid 35215073)
    • (2002) Biological Chemistry , vol.383 , Issue.7-8 , pp. 1237-1248
    • Demoz, M.1    Castino, R.2    Cesaro, P.3    Baccino, F.M.4    Bonelli, G.5    Isidoro, C.6
  • 40
    • 0029782494 scopus 로고    scopus 로고
    • Cathepsin D protease mediates programmed cell death induced by interferon-γ, Fas/APO-1 and TNF-α
    • Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J 1996;15:3861-3870. (Pubitemid 26289796)
    • (1996) EMBO Journal , vol.15 , Issue.15 , pp. 3861-3870
    • Deiss, L.P.1    Galinka, H.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 41
    • 0034650786 scopus 로고    scopus 로고
    • Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes
    • DOI 10.1006/abbi.1999.1567
    • Ollinger K. Inhibition of cathepsin D prevents free-radicalinduced apoptosis in rat cardiomyocytes. Arch Biochem Biophys 2000;373:346-351. (Pubitemid 30068972)
    • (2000) Archives of Biochemistry and Biophysics , vol.373 , Issue.2 , pp. 346-351
    • Ollinger, K.1
  • 42
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?
    • DOI 10.1038/sj.bjp.0705776
    • Halliwell B, Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol 2004;142: 231-255. (Pubitemid 38746160)
    • (2004) British Journal of Pharmacology , vol.142 , Issue.2 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 43
    • 33749386845 scopus 로고    scopus 로고
    • The effect of δ-elemene on hela cell lines by apoptosis induction
    • DOI 10.1248/yakushi.126.979
    • Wang XS, Yang W, Tao SJ, Li K, Li M, Dong JH, Wang MW. Effect of delta-elemene on Hela cell lines by apoptosis induction. Yakugaku Zasshi 2006;126:979-990. (Pubitemid 44506560)
    • (2006) Yakugaku Zasshi , vol.126 , Issue.10 , pp. 979-990
    • Wang, X.-S.1    Yang, W.2    Tao, S.-J.3    Li, K.4    Li, M.5    Dong, J.-H.6    Wang, M.-W.7
  • 44
    • 70450162214 scopus 로고    scopus 로고
    • Cell apoptosis induced by delta-elemene in colorectal adenocarcinoma cells via a mitochondrial-mediated pathway
    • Xie CY, Yang W, Li M, Ying J, Tao SJ, Li K, et al. Cell apoptosis induced by delta-elemene in colorectal adenocarcinoma cells via a mitochondrial- mediated pathway. Yakugaku Zasshi 2009;129:1403-1413.
    • (2009) Yakugaku Zasshi , vol.129 , pp. 1403-1413
    • Xie, C.Y.1    Yang, W.2    Li, M.3    Ying, J.4    Tao, S.J.5    Li, K.6
  • 45
    • 49349110132 scopus 로고    scopus 로고
    • N-(beta-Elemene-13-yl) tryptophan methyl ester induces apoptosis in human leukemia cells and synergizes with arsenic trioxide through a hydrogen peroxide dependent pathway
    • Yu Z, Wang R, Xu L, Dong J, Jing Y. N-(beta-Elemene-13-yl) tryptophan methyl ester induces apoptosis in human leukemia cells and synergizes with arsenic trioxide through a hydrogen peroxide dependent pathway. Cancer Lett 2008; 269:165-173.
    • (2008) Cancer Lett , vol.269 , pp. 165-173
    • Yu, Z.1    Wang, R.2    Xu, L.3    Dong, J.4    Jing, Y.5
  • 46
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 2000; 29:222-230.
    • (2000) Free Radic Biol Med , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 47
    • 0141447370 scopus 로고    scopus 로고
    • Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
    • DOI 10.1046/j.1432-1033.2003.03765.x
    • Zhao M, Antunes F, Eaton JW, Brunk UT. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur J Biochem 2003;270: 3778-3786. (Pubitemid 37123249)
    • (2003) European Journal of Biochemistry , vol.270 , Issue.18 , pp. 3778-3786
    • Zhao, M.1    Antunes, F.2    Eaton, J.W.3    Brunk, U.T.4
  • 48
    • 0030758614 scopus 로고    scopus 로고
    • Comparative studies of enhanced ironmediated production of hydroxyl radical by glutathione, cysteine, ascorbic acid, and selected catechols
    • Nappi AJ, Vass E. Comparative studies of enhanced ironmediated production of hydroxyl radical by glutathione, cysteine, ascorbic acid, and selected catechols. Biochim Biophys Acta 1997;1336:295-302.
    • (1997) Biochim Biophys Acta , vol.1336 , pp. 295-302
    • Nappi, A.J.1    Vass, E.2
  • 49
    • 45949113951 scopus 로고
    • Relationships among cytotoxicity, lysosomal breakdown, chromosome aberrations, and DNA double-strand breaks
    • Bradley MO, Taylor VI, Armstrong MJ, Galloway SM. Relationships among cytotoxicity, lysosomal breakdown, chromosome aberrations, and DNA double-strand breaks. Mutat Res 1987;189:69-79.
    • (1987) Mutat Res , vol.189 , pp. 69-79
    • Bradley, M.O.1    Taylor, V.I.2    Armstrong, M.J.3    Galloway, S.M.4
  • 50
    • 2342459790 scopus 로고    scopus 로고
    • DNA damage-induced apoptosis
    • DOI 10.1038/sj.onc.1207532
    • Norbury CJ, Zhivotovsky B. DNA damage-induced apoptosis. Oncogene 2004;23:2797-2808. (Pubitemid 38638843)
    • (2004) Oncogene , vol.23 , Issue.16 REV. ISSUE 2 , pp. 2797-2808
    • Norbury, C.J.1    Zhivotovsky, B.2
  • 51
    • 0035793580 scopus 로고    scopus 로고
    • Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
    • Stoka V, Turk B, Schendel SL, Kim TH, Cirman T, Snipas SJ, et al. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 2001;276:3149-3157.
    • (2001) J Biol Chem , vol.276 , pp. 3149-3157
    • Stoka, V.1    Turk, B.2    Schendel, S.L.3    Kim, T.H.4    Cirman, T.5    Snipas, S.J.6
  • 52
    • 0036732169 scopus 로고    scopus 로고
    • Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage
    • DOI 10.1038/sj.cdd.4401048
    • Reiners JJ Jr, Caruso JA, Mathieu P, Chelladurai B, Yin XM, Kessel D. Release of cytochrome c and activation of procaspase-9 following lysosomal photodamage involves Bid cleavage. Cell Death Differ 2002;9:934-944. (Pubitemid 35033432)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.9 , pp. 934-944
    • Reiners Jr., J.J.1    Caruso, J.A.2    Mathieu, P.3    Chelladurai, B.4    Yin, X.-M.5    Kessel, D.6
  • 53
    • 0942265544 scopus 로고    scopus 로고
    • Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
    • DOI 10.1074/jbc.M308347200
    • Cirman T, Oresi K, Mazovec GD, Turk V, Reed JC, Myers RM, et al. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem 2004;279:3578-3587. (Pubitemid 38140598)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.5 , pp. 3578-3587
    • Cirman, T.1    Oresic, K.2    Mazovec, G.D.3    Turk, V.4    Reed, J.C.5    Myers, R.M.6    Salvesen, G.S.7    Turk, B.8
  • 55
    • 0043234207 scopus 로고    scopus 로고
    • Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis
    • DOI 10.1074/jbc.M301911200
    • Bid è re N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C, Senik A. Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis. J Biol Chem 2003;278:31401-31411. (Pubitemid 36994661)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.33 , pp. 31401-31411
    • Bidere, N.1    Lorenzo, H.K.2    Carmona, S.3    Laforge, M.4    Harper, F.5    Dumont, C.6    Senik, A.7
  • 56
    • 0035861903 scopus 로고    scopus 로고
    • Delayed oxidant-induced cell death involves activation of phospholipase A2
    • DOI 10.1016/S0014-5793(01)03184-2, PII S0014579301031842
    • Zhao M, Brunk UT, Eaton JW. Delayed oxidant-induced cell death involves activation of phospholipase A2. FEBS Lett 2001;509:399-404. (Pubitemid 34031968)
    • (2001) FEBS Letters , vol.509 , Issue.3 , pp. 399-404
    • Zhao, M.1    Brunk, U.T.2    Eaton, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.