Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis

Free Radical Biology and Medicine

Volumn 30, Issue 12, 2001, Pages 1347-1356

  Daré, Elisabetta ^a   Li, Wei ^b   Zhivotovsky, Boris ^a   Yuan, Ximing ^b   Ceccatelli, Sandra ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Caspases; DNA fragmentation; Free radicals; Hydrogen peroxide; Lysosomes; Methylmercury; Mitochondrial potential

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; DNA FRAGMENT; HYDROGEN PEROXIDE; HYDROLASE; METHYLMERCURY; NEUROTOXIN;

APOPTOSIS; ARTICLE; ASTROCYTOMA; ASTROCYTOMA CELL; CELL DAMAGE; CELL LINE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYSOSOME; LYSOSOME MEMBRANE; MITOCHONDRION; NERVE CELL LESION; OXIDATIVE STRESS; PRIORITY JOURNAL; RUPTURE;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; ASTROCYTES; ASTROCYTOMA; BRAIN NEOPLASMS; CASPASES; CELL MEMBRANE PERMEABILITY; CYCLOSPORINE; CYSTEINE PROTEINASE INHIBITORS; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; LYSOSOMES; MEMBRANE POTENTIALS; METHYLMERCURY COMPOUNDS; OXIDATIVE STRESS; TUMOR CELLS, CULTURED;

EID: 0035877037     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00526-3     Document Type: Article

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