-
1
-
-
33847363203
-
Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ
-
DOI 10.1172/JCI30542
-
Iredale, J. P. 2007. Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J. Clin. Invest. 117: 539-548. (Pubitemid 46348508)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 539-548
-
-
Iredale, J.P.1
-
2
-
-
42949163491
-
Mechanisms of Hepatic Fibrogenesis
-
DOI 10.1053/j.gastro.2008.03.003, PII S0016508508004290
-
Friedman, S. L. 2008. Mechanisms of hepatic fibrogenesis. Gastroenterology 134: 1655-1669. (Pubitemid 351615417)
-
(2008)
Gastroenterology
, vol.134
, Issue.6
, pp. 1655-1669
-
-
Friedman, S.L.1
-
3
-
-
0037716406
-
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats
-
DOI 10.1016/S0016-5085(03)00666-8
-
Dooley, S., J. Hamzavi, K. Breitkopf, E. Wiercinska, H. M. Said, J. Lorenzen, P. Ten Dijke, and A. M. Gressner. 2003. Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. Gastroenterology 125: 178-191. (Pubitemid 36799118)
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 178-191
-
-
Dooley, S.1
Hamzavi, J.2
Breitkopf, K.3
Wiercinska, E.4
Said, H.M.5
Lorenzen, J.6
Ten, D.P.7
Gressner, A.M.8
-
5
-
-
0034767501
-
Transforming growth factor beta and the liver
-
DOI 10.1053/jhep.2001.28457
-
Bissell, D. M., D. Roulot, and J. George. 2001. Transforming growth factor beta and the liver. Hepatology 34: 859-867. (Pubitemid 33032019)
-
(2001)
Hepatology
, vol.34
, Issue.5
, pp. 859-867
-
-
Bissell, D.M.1
Roulot, D.2
George, J.3
-
7
-
-
0037775352
-
IL-13 effector functions
-
DOI 10.1146/annurev.immunol.21.120601.141142
-
Wynn, T. A. 2003. IL-13 effector functions. Annu. Rev. Immunol. 21: 425-456. (Pubitemid 37174537)
-
(2003)
Annual Review of Immunology
, vol.21
, pp. 425-456
-
-
Wynn, T.A.1
-
8
-
-
3543107212
-
Fibrotic disease and the T(H)1/T(H)2 paradigm
-
Wynn, T. A. 2004. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4: 583-594.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 583-594
-
-
Wynn, T.A.1
-
9
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
DOI 10.1002/path.2277
-
Wynn, T. A. 2008. Cellular and molecular mechanisms of fibrosis. J. Pathol. 214: 199-210. (Pubitemid 351160157)
-
(2008)
Journal of Pathology
, vol.214
, Issue.2
, pp. 199-210
-
-
Wynn, T.A.1
-
10
-
-
0027413678
-
Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function
-
McKenzie, A. N., J. A. Culpepper, R. De Waal Malefyt, F. Brière, J. Punnonen, G. Aversa, A. Sato, W. Dang, B. G. Cocks, S. Menon, et al. 1993. Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc. Natl. Acad. Sci. USA 90: 3735-3739. (Pubitemid 23111442)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.8
, pp. 3735-3739
-
-
McKenzie, A.N.J.1
Culpepper, J.A.2
De Waal, M.R.3
Briere, F.4
Punnonen, J.5
Aversa, G.6
Sato, A.7
Dang, W.8
Cocks, B.G.9
Menon, S.10
De Vries, J.E.11
Banchereau, J.12
Zurawski, G.13
-
11
-
-
0027464685
-
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses
-
DOI 10.1038/362248a0
-
Minty, A., P. Chalon, J. M. Derocq, X. Dumont, J. C. Guillemot, M. Kaghad, C. Labit, P. Leplatois, P. Liauzun, B. Miloux, et al. 1993. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362: 248-250. (Pubitemid 23093630)
-
(1993)
Nature
, vol.362
, Issue.6417
, pp. 248-250
-
-
Minty, A.1
Chalon, P.2
Derocq, J.-M.3
Dumont, X.4
Guillemot, J.-C.5
Keghad, M.6
Labit, C.7
Leplatois, P.8
Liauzun, P.9
Miloux, B.10
Minty, C.11
Casellas, P.12
Loison, G.13
Lupker, J.14
Shire, D.15
Ferrara, P.16
Caput, D.17
-
12
-
-
0027522374
-
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells
-
Punnonen, J., G. Aversa, B. G. Cocks, A. N. McKenzie, S. Menon, G. Zurawski, R. De Waal Malefyt, and J. E. De Vries. 1993. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. USA 90: 3730-3734. (Pubitemid 23111441)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.8
, pp. 3730-3734
-
-
Punnonen, J.1
Aversa, G.2
Cocks, B.G.3
McKenzie, A.N.J.4
Menon, S.5
Zurawski, G.6
De Waal, M.R.7
De Vries, J.E.8
-
13
-
-
0027274890
-
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
-
Zurawski, S. M., F. Vega, Jr., B. Huyghe, and G. Zurawski. 1993. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J. 12: 2663-2670. (Pubitemid 23218315)
-
(1993)
EMBO Journal
, vol.12
, Issue.7
, pp. 2663-2670
-
-
Zurawsli, S.M.1
Vega Jr., F.2
Huyghe, B.3
Zurawski, G.4
-
14
-
-
0034163317
-
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent
-
Fallon, P. G., E. J. Richardson, G. J. McKenzie, and A. N. McKenzie. 2000. Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent. J. Immunol. 164: 2585-2591. (Pubitemid 30115489)
-
(2000)
Journal of Immunology
, vol.164
, Issue.5
, pp. 2585-2591
-
-
Fallon, P.G.1
Richardson, E.J.2
McKenzie, G.J.3
McKenzie, A.N.J.4
-
15
-
-
0032697042
-
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
-
Chiaramonte, M. G., D. D. Donaldson, A. W. Cheever, and T. A. Wynn. 1999. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J. Clin. Invest. 104: 777-785. (Pubitemid 29536363)
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.6
, pp. 777-785
-
-
Chiaramonte, M.G.1
Donaldson, D.D.2
Cheever, A.W.3
Wynn, T.A.4
-
16
-
-
1642333177
-
Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts
-
Kolodsick, J. E., G. B. Toews, C. Jakubzick, C. Hogaboam, T. A. Moore, A. McKenzie, C. A. Wilke, C. J. Chrisman, and B. B. Moore. 2004. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J. Immunol. 172: 4068-4076. (Pubitemid 38375218)
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4068-4076
-
-
Kolodsick, J.E.1
Toews, G.B.2
Jakubzick, C.3
Hogaboam, C.4
Moore, T.A.5
McKenzie, A.6
Wilke, C.A.7
Chrisman, C.J.8
Moore, B.B.9
-
17
-
-
0036679426
-
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling
-
DOI 10.1172/JCI200214136
-
Lanone, S., T. Zheng, Z. Zhu, W. Liu, C. G. Lee, B. Ma, Q. Chen, R. J. Homer, J. Wang, L. A. Rabach, et al. 2002. Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J. Clin. Invest. 110: 463-474. (Pubitemid 34919700)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.4
, pp. 463-474
-
-
Lanone, S.1
Zheng, T.2
Zhu, Z.3
Liu, W.4
Lee, C.G.5
Ma, B.6
Chen, Q.7
Homer, R.J.8
Wang, J.9
Rabach, L.A.10
Rabach, M.E.11
Michael, S.J.12
Shapiro, S.D.13
Senior, R.M.14
Elias, J.A.15
-
18
-
-
58149306389
-
Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model
-
Shimamura, T., T. Fujisawa, S. R. Husain, M. Kioi, A. Nakajima, and R. K. Puri. 2008. Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J. Immunol. 181: 4656-4665.
-
(2008)
J. Immunol.
, vol.181
, pp. 4656-4665
-
-
Shimamura, T.1
Fujisawa, T.2
Husain, S.R.3
Kioi, M.4
Nakajima, A.5
Puri, R.K.6
-
19
-
-
4644225081
-
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent
-
Kaviratne, M., M. Hesse, M. Leusink, A. W. Cheever, S. J. Davies, J. H. McKerrow, L. M. Wakefield, J. J. Letterio, and T. A. Wynn. 2004. IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent. J. Immunol. 173: 4020-4029. (Pubitemid 39280766)
-
(2004)
Journal of Immunology
, vol.173
, Issue.6
, pp. 4020-4029
-
-
Kaviratne, M.1
Hesse, M.2
Leusink, M.3
Cheever, A.W.4
Davies, S.J.5
McKerrow, J.H.6
Wakefield, L.M.7
Letterio, J.J.8
Wynn, T.A.9
-
20
-
-
0031944290
-
Regulation of immune responses by TGF-beta
-
Letterio, J. J., and A. B. Roberts. 1998. Regulation of immune responses by TGF-beta. Annu. Rev. Immunol. 16: 137-161.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 137-161
-
-
Letterio, J.J.1
Roberts, A.B.2
-
21
-
-
15244339164
-
Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis
-
DOI 10.1172/JCI200419603
-
Daniels, C. E., M. C. Wilkes, M. Edens, T. J. Kottom, S. J. Murphy, A. H. Limper, and E. B. Leof. 2004. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J. Clin. Invest. 114: 1308-1316. (Pubitemid 40385302)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
Leof, E.B.7
-
22
-
-
48949084865
-
Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
-
Gressner, O. A., and A. M. Gressner. 2008. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int. 28: 1065-1079.
-
(2008)
Liver Int.
, vol.28
, pp. 1065-1079
-
-
Gressner, O.A.1
Gressner, A.M.2
-
23
-
-
68949101788
-
Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes - But without modulating bone morphogenetic protein 7 signaling
-
Gressner, O. A., B. Lahme, M. Siluschek, K. Rehbein, R. Weiskirchen, and A. M. Gressner. 2009. Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes - but without modulating bone morphogenetic protein 7 signaling. Hepatology 49: 2021-2030.
-
(2009)
Hepatology
, vol.49
, pp. 2021-2030
-
-
Gressner, O.A.1
Lahme, B.2
Siluschek, M.3
Rehbein, K.4
Weiskirchen, R.5
Gressner, A.M.6
-
24
-
-
0035476418
-
Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy
-
DOI 10.1042/0264-6021:3590077
-
Wahab, N. A., N. Yevdokimova, B. S. Weston, T. Roberts, X. J. Li, H. Brinkman, and R. M. Mason. 2001. Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy. Biochem. J. 359: 77-87. (Pubitemid 32939209)
-
(2001)
Biochemical Journal
, vol.359
, Issue.1
, pp. 77-87
-
-
Wahab, N.A.1
Yevdokimova, N.2
Weston, B.S.3
Roberts, T.4
Li, X.J.5
Brinkman, H.6
Mason, R.M.7
-
25
-
-
0033957976
-
Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
-
Riser, B. L., M. Denichilo, P. Cortes, C. Baker, J. M. Grondin, J. Yee, and R. G. Narins. 2000. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J. Am. Soc. Nephrol. 11: 25-38. (Pubitemid 30020423)
-
(2000)
Journal of the American Society of Nephrology
, vol.11
, Issue.1
, pp. 25-38
-
-
Riser, B.L.1
Denichilo, M.2
Cortes, P.3
Baker, C.4
Grondin, J.M.5
Yee, J.6
Narins, R.G.7
-
26
-
-
0031225015
-
Connective tissue growth factor: A mediator of TGf-beta action on fibroblasts
-
DOI 10.1016/S1359-6101(97)00010-5, PII S1359610197000105
-
Grotendorst, G. R. 1997. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 8: 171-179. (Pubitemid 28077925)
-
(1997)
Cytokine and Growth Factor Reviews
, vol.8
, Issue.3
, pp. 171-179
-
-
Grotendorst, G.R.1
-
27
-
-
2142646426
-
TGF-beta signaling and the fibrotic response
-
Leask, A., and D. J. Abraham. 2004. TGF-beta signaling and the fibrotic response. FASEB J. 18: 816-827.
-
(2004)
FASEB J.
, vol.18
, pp. 816-827
-
-
Leask, A.1
Abraham, D.J.2
-
28
-
-
1642452822
-
Insights into the Molecular Mechanism of Chronic Fibrosis: The Role of Connective Tissue Growth Factor in Scleroderma
-
DOI 10.1046/j.0022-202X.2003.22133.x
-
Leask, A., C. P. Denton, and D. J. Abraham. 2004. Insights into the molecular mechanism of chronic fibrosis: the role of connective tissue growth factor in scleroderma. J. Invest. Dermatol. 122: 1-6. (Pubitemid 38114631)
-
(2004)
Journal of Investigative Dermatology
, vol.122
, Issue.1
, pp. 1-6
-
-
Leask, A.1
Denton, C.P.2
Abraham, D.J.3
-
29
-
-
0035066961
-
Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis
-
Sedlaczek, N., J. D. Jia, M. Bauer, H. Herbst, M. Ruehl, E. G. Hahn, and D. Schuppan. 2001. Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. Am. J. Pathol. 158: 1239-1244. (Pubitemid 32281287)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.4
, pp. 1239-1244
-
-
Sedlaczek, N.1
Jia, J.-D.2
Bauer, M.3
Herbst, H.4
Ruehl, M.5
Hahn, E.G.6
Schuppan, D.7
-
30
-
-
36348932917
-
Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
-
DOI 10.1002/hep.21806
-
Weng, H. L., L. Ciuclan, Y. Liu, J. Hamzavi, P. Godoy, H. Gaitantzi, S. Kanzler, R. Heuchel, U. Ueberham, R. Gebhardt, et al. 2007. Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. Hepatology 46: 1257-1270. (Pubitemid 350144790)
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 1257-1270
-
-
Weng, H.-L.1
Ciuclan, L.2
Liu, Y.3
Hamzavi, J.4
Godoy, P.5
Gaitantzi, H.6
Kanzler, S.7
Heuchel, R.8
Ueberham, U.9
Gebhardt, R.10
Breitkopf, K.11
Dooley, S.12
-
31
-
-
0029808645
-
A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene
-
Grotendorst, G. R., H. Okochi, and N. Hayashi. 1996. A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ. 7: 469-480. (Pubitemid 26362091)
-
(1996)
Cell Growth and Differentiation
, vol.7
, Issue.4
, pp. 469-480
-
-
Grotendorst, G.R.1
Okochi, H.2
Hayashi, N.3
-
32
-
-
34848865661
-
Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes
-
DOI 10.1016/j.jhep.2007.05.015, PII S0168827807003479
-
Gressner, O. A., B. Lahme, I. Demirci, A. M. Gressner, and R. Weiskirchen. 2007. Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. J. Hepatol. 47: 699-710. (Pubitemid 47503426)
-
(2007)
Journal of Hepatology
, vol.47
, Issue.5
, pp. 699-710
-
-
Gressner, O.A.1
Lahme, B.2
Demirci, I.3
Gressner, A.M.4
Weiskirchen, R.5
-
33
-
-
67651165609
-
The etiology of liver damage imparts cytokines transforming growth factor beta1 or interleukin-13 as driving forces in fibrogenesis
-
Weng, H. L., Y. Liu, J. L. Chen, T. Huang, L. J. Xu, P. Godoy, J. H. Hu, C. Zhou, F. Stickel, A. Marx, et al. 2009. The etiology of liver damage imparts cytokines transforming growth factor beta1 or interleukin-13 as driving forces in fibrogenesis. Hepatology 50: 230-243.
-
(2009)
Hepatology
, vol.50
, pp. 230-243
-
-
Weng, H.L.1
Liu, Y.2
Chen, J.L.3
Huang, T.4
Xu, L.J.5
Godoy, P.6
Hu, J.H.7
Zhou, C.8
Stickel, F.9
Marx, A.10
-
34
-
-
0023275798
-
The synthesis of proteoglycans in fat-storing cells of rat liver
-
Schäfer, S., O. Zerbe, and A. M. Gressner. 1987. The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology 7: 680-687. (Pubitemid 17130709)
-
(1987)
Hepatology
, vol.7
, Issue.4
, pp. 680-687
-
-
Schafer, S.1
Zerbe, O.2
Gressner, A.M.3
-
35
-
-
0037393323
-
IL-13 receptors and signaling pathways: An evolving web
-
quiz 691
-
Hershey, G. K. 2003. IL-13 receptors and signaling pathways: an evolving web. J. Allergy Clin. Immunol. 111: 677-690, quiz 691.
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 677-690
-
-
Hershey, G.K.1
-
36
-
-
0029035685
-
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor
-
Zurawski, S. M., P. Chomarat, O. Djossou, C. Bidaud, A. N. McKenzie, P. Miossec, J. Banchereau, and G. Zurawski. 1995. The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor. J. Biol. Chem. 270: 13869-13878.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13869-13878
-
-
Zurawski, S.M.1
Chomarat, P.2
Djossou, O.3
Bidaud, C.4
McKenzie, A.N.5
Miossec, P.6
Banchereau, J.7
Zurawski, G.8
-
37
-
-
48549084059
-
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage
-
Dooley, S., J. Hamzavi, L. Ciuclan, P. Godoy, I. Ilkavets, S. Ehnert, E. Ueberham, R. Gebhardt, S. Kanzler, A. Geier, et al. 2008. Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage. Gastroenterology 135: 642-659.
-
(2008)
Gastroenterology
, vol.135
, pp. 642-659
-
-
Dooley, S.1
Hamzavi, J.2
Ciuclan, L.3
Godoy, P.4
Ilkavets, I.5
Ehnert, S.6
Ueberham, E.7
Gebhardt, R.8
Kanzler, S.9
Geier, A.10
-
38
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
DOI 10.1016/S0092-8674(03)00432-X
-
Shi, Y., and J. Massagué. 2003. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700. (Pubitemid 36724933)
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
39
-
-
0033531948
-
Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- And activin-mediated growth arrest and apoptosis in B cells
-
Ishisaki, A., K. Yamato, S. Hashimoto, A. Nakao, K. Tamaki, K. Nonaka, P. ten Dijke, H. Sugino, and T. Nishihara. 1999. Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells. J. Biol. Chem. 274: 13637-13642.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13637-13642
-
-
Ishisaki, A.1
Yamato, K.2
Hashimoto, S.3
Nakao, A.4
Tamaki, K.5
Nonaka, K.6
Ten Dijke, P.7
Sugino, H.8
Nishihara, T.9
-
40
-
-
75649127963
-
Bone morphogenetic protein receptors and signal transduction
-
Miyazono, K., Y. Kamiya, and M. Morikawa. 2010. Bone morphogenetic protein receptors and signal transduction. J. Biochem. 147: 35-51.
-
(2010)
J. Biochem.
, vol.147
, pp. 35-51
-
-
Miyazono, K.1
Kamiya, Y.2
Morikawa, M.3
-
41
-
-
0036174529
-
Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma
-
Blease, K., J. M. Schuh, C. Jakubzick, N. W. Lukacs, S. L. Kunkel, B. H. Joshi, R. K. Puri, M. H. Kaplan, and C. M. Hogaboam. 2002. Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. Am. J. Pathol. 160: 481-490. (Pubitemid 34160325)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.2
, pp. 481-490
-
-
Blease, K.1
Schuh, J.M.2
Jakubzick, C.3
Lukacs, N.W.4
Kunkel, S.L.5
Joshi, B.H.6
Puri, R.K.7
Kaplan, M.H.8
Hogaboam, C.M.9
-
42
-
-
77949395650
-
Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling
-
Chung, A. C., H. Zhang, Y. Z. Kong, J. J. Tan, X. R. Huang, J. B. Kopp, and H. Y. Lan. 2010. Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling. J. Am. Soc. Nephrol. 21: 249-260.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 249-260
-
-
Chung, A.C.1
Zhang, H.2
Kong, Y.Z.3
Tan, J.J.4
Huang, X.R.5
Kopp, J.B.6
Lan, H.Y.7
-
43
-
-
1342268353
-
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
-
Li, J. H., X. R. Huang, H. J. Zhu, M. Oldfield, M. Cooper, L. D. Truong, R. J. Johnson, and H. Y. Lan. 2004. Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J. 18: 176-178.
-
(2004)
FASEB J.
, vol.18
, pp. 176-178
-
-
Li, J.H.1
Huang, X.R.2
Zhu, H.J.3
Oldfield, M.4
Cooper, M.5
Truong, L.D.6
Johnson, R.J.7
Lan, H.Y.8
-
44
-
-
9644284528
-
Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway
-
Zhou, G., C. Li, and L. Cai. 2004. Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway. Am. J. Pathol. 165: 2033-2043. (Pubitemid 39578381)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.6
, pp. 2033-2043
-
-
Zhou, G.1
Li, C.2
Cai, L.3
-
45
-
-
0035903306
-
1
-
DOI 10.1084/jem.194.6.809
-
Lee, C. G., R. J. Homer, Z. Zhu, S. Lanone, X. Wang, V. Koteliansky, J. M. Shipley, P. Gotwals, P. Noble, Q. Chen, et al. 2001. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J. Exp. Med. 194: 809-821. (Pubitemid 32983016)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.6
, pp. 809-821
-
-
Chun, G.L.1
Homer, R.J.2
Zhu, Z.3
Lanone, S.4
Wang, X.5
Koteliansky, V.6
Shipley, J.M.7
Gotwals, P.8
Noble, P.9
Chen, Q.10
Senior, R.M.11
Elias, J.A.12
-
46
-
-
33845599489
-
IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads
-
DOI 10.1016/j.jhep.2006.09.014, PII S0168827806005502
-
Weng, H., P. R. Mertens, A. M. Gressner, and S. Dooley. 2007. IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads. J. Hepatol. 46: 295-303. (Pubitemid 44959156)
-
(2007)
Journal of Hepatology
, vol.46
, Issue.2
, pp. 295-303
-
-
Weng, H.1
Mertens, P.R.2
Gressner, A.M.3
Dooley, S.4
-
47
-
-
0141428794
-
Controlling the angiogenic switch: A balance between two distinct TGF-b receptor signaling pathways
-
DOI 10.1016/S1050-1738(03)00142-7, PII S1050173803001427
-
Goumans, M. J., F. Lebrin, and G. Valdimarsdottir. 2003. Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways. Trends Cardiovasc. Med. 13: 301-307. (Pubitemid 37159396)
-
(2003)
Trends in Cardiovascular Medicine
, vol.13
, Issue.7
, pp. 301-307
-
-
Goumans, M.-J.1
Lebrin, F.2
Valdimarsdottir, G.3
-
48
-
-
0242330126
-
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
-
DOI 10.1016/S1097-2765(03)00386-1
-
Goumans, M. J., G. Valdimarsdottir, S. Itoh, F. Lebrin, J. Larsson, C. Mummery, S. Karlsson, and P. ten Dijke. 2003. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol. Cell 12: 817-828. (Pubitemid 37352776)
-
(2003)
Molecular Cell
, vol.12
, Issue.4
, pp. 817-828
-
-
Goumans, M.-J.1
Valdimarsdottir, G.2
Itoh, S.3
Lebrin, F.4
Larsson, J.5
Mummery, C.6
Karlsson, S.7
Ten, D.P.8
-
49
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
-
DOI 10.1093/emboj/21.7.1743
-
Goumans, M. J., G. Valdimarsdottir, S. Itoh, A. Rosendahl, P. Sideras, and P. ten Dijke. 2002. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J. 21: 1743-1753. (Pubitemid 34614630)
-
(2002)
EMBO Journal
, vol.21
, Issue.7
, pp. 1743-1753
-
-
Goumans, M.-J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
Ten, D.P.6
-
50
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
DOI 10.1038/nchembio.2007.54, PII NCHEMBIO200754
-
Yu, P. B., C. C. Hong, C. Sachidanandan, J. L. Babitt, D. Y. Deng, S. A. Hoyng, H. Y. Lin, K. D. Bloch, and R. T. Peterson. 2008. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat. Chem. Biol. 4: 33-41. (Pubitemid 350273653)
-
(2008)
Nature Chemical Biology
, vol.4
, Issue.1
, pp. 33-41
-
-
Yu, P.B.1
Hong, C.C.2
Sachidanandan, C.3
Babitt, J.L.4
Deng, D.Y.5
Hoyng, S.A.6
Lin, H.Y.7
Bloch, K.D.8
Peterson, R.T.9
-
51
-
-
0037451128
-
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response
-
DOI 10.1084/jem.20020903
-
Chiaramonte, M. G., M. Mentink-Kane, B. A. Jacobson, A. W. Cheever, M. J. Whitters, M. E. Goad, A. Wong, M. Collins, D. D. Donaldson, M. J. Grusby, and T. A. Wynn. 2003. Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. J. Exp. Med. 197: 687-701. (Pubitemid 36350864)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.6
, pp. 687-701
-
-
Chiaramonte, M.G.1
Mentink-Kane, M.2
Jacobson, B.A.3
Cheever, A.W.4
Whitters, M.J.5
Goad, M.E.P.6
Wong, A.7
Collins, M.8
Donaldson, D.D.9
Grusby, M.J.10
Wynn, T.A.11
-
52
-
-
0031587927
-
Expression of recombinant rat interleukin-13 (IL-13) and generation of a neutralizing rat IL-13 antiserum
-
DOI 10.1006/bbrc.1997.6832
-
Lakkis, F. G., E. N. Cruet, G. M. Nassar, K. F. Badr, and D. W. Pascual. 1997. Expression of recombinant rat interleukin-13 (IL-13) and generation of a neutralizing rat IL-13 antiserum. Biochem. Biophys. Res. Commun. 235: 529-532. (Pubitemid 27326514)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.235
, Issue.3
, pp. 529-532
-
-
Lakkis, F.G.1
Cruet, E.N.2
Nassar, G.M.3
Badr, K.F.4
Pascual, D.W.5
-
54
-
-
41949121773
-
Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: The A-549 cell bioassay
-
Miller, R., R. Sadhukhan, and C. Wu. 2008. Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: the A-549 cell bioassay. J. Immunol. Methods 334: 134-141.
-
(2008)
J. Immunol. Methods
, vol.334
, pp. 134-141
-
-
Miller, R.1
Sadhukhan, R.2
Wu, C.3
|