Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: The A-549 cell bioassay

Journal of Immunological Methods

Volumn 334, Issue 1-2, 2008, Pages 134-141

  Miller, Renee ^a   Sadhukhan, Ramkrishna ^a   Wu, Chengbin ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

A 549; Bioassay; IL 13 antagonist; IL 13 antibody; In vitro; Potency; TARC ELISA (Enzyme Linked Immunosorbent Assay)

Indexed keywords

CYTOKINE RECEPTOR ANTAGONIST; INTERLEUKIN 13 ANTIBODY; INTERLEUKIN 13 RECEPTOR BLOCKING AGENT; RECOMBINANT INTERLEUKIN 13; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CHEMOKINE CCL17; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-13 RECEPTOR ALPHA2 SUBUNIT; INTERLEUKIN-2; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 41949121773     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2008.02.009     Document Type: Article

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