-
1
-
-
0034090602
-
Anti-inflammatory cytokines
-
Opal, S.M., and V.A. DePalo. 2000. Anti-inflammatory cytokines. Chest. 117:1162-1172.
-
(2000)
Chest
, vol.117
, pp. 1162-1172
-
-
Opal, S.M.1
DePalo, V.A.2
-
2
-
-
0033178829
-
The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections
-
Finkelman, F.D., T.A. Wynn, D.D. Donaldson, and J.F. Urban. 1999. The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections. Curr. Opin. Immunol. 11:420-426.
-
(1999)
Curr. Opin. Immunol.
, vol.11
, pp. 420-426
-
-
Finkelman, F.D.1
Wynn, T.A.2
Donaldson, D.D.3
Urban, J.F.4
-
3
-
-
0029959459
-
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha
-
Gazzinelli, R.T., M. Wysocka, S. Hieny, T. Scharton-Kersten, A. Cheever, R. Kuhn, W. Muller, G. Trinchieri, and A. Sher. 1996. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J. Immunol. 157:798-805.
-
(1996)
J. Immunol.
, vol.157
, pp. 798-805
-
-
Gazzinelli, R.T.1
Wysocka, M.2
Hieny, S.3
Scharton-Kersten, T.4
Cheever, A.5
Kuhn, R.6
Muller, W.7
Trinchieri, G.8
Sher, A.9
-
4
-
-
0031112271
-
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi
-
Hunter, C.A., L.A. Ellis-Neyes, T. Slifer, S. Kanaly, G. Grunig, M. Fort, D. Rennick, and F.G. Araujo. 1997. IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. J. Immunol. 158:3311-3316.
-
(1997)
J. Immunol.
, vol.158
, pp. 3311-3316
-
-
Hunter, C.A.1
Ellis-Neyes, L.A.2
Slifer, T.3
Kanaly, S.4
Grunig, G.5
Fort, M.6
Rennick, D.7
Araujo, F.G.8
-
5
-
-
0034660272
-
IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis
-
Hoffmann, K.F., A.W. Cheever, and T.A. Wynn. 2000. IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis. J. Immunol. 164:6406-6416.
-
(2000)
J. Immunol.
, vol.164
, pp. 6406-6416
-
-
Hoffmann, K.F.1
Cheever, A.W.2
Wynn, T.A.3
-
6
-
-
0035514724
-
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions
-
Hoffmann, K.F., T.C. McCarty, D.H. Segal, M. Chiaramonte, M. Hesse, E.M. Davis, A.W. Cheever, P.S. Meltzer, H.C. Morse III, and T.A. Wynn. 2001. Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions. FASEB J. 15:2545-2547.
-
(2001)
FASEB J.
, vol.15
, pp. 2545-2547
-
-
Hoffmann, K.F.1
McCarty, T.C.2
Segal, D.H.3
Chiaramonte, M.4
Hesse, M.5
Davis, E.M.6
Cheever, A.W.7
Meltzer, P.S.8
Morse H.C. III9
Wynn, T.A.10
-
7
-
-
0034923170
-
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis
-
Chiaramonte, M.G., A.W. Cheever, J.D. Malley, D.D. Donaldson, and T.A. Wynn. 2001. Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis. Hepatology. 34:273-282.
-
(2001)
Hepatology
, vol.34
, pp. 273-282
-
-
Chiaramonte, M.G.1
Cheever, A.W.2
Malley, J.D.3
Donaldson, D.D.4
Wynn, T.A.5
-
8
-
-
0029166483
-
Cytokine regulation of granuloma formation in schistosomiasis
-
Wynn, T.A., and A.W. Cheever. 1995. Cytokine regulation of granuloma formation in schistosomiasis. Curr. Opin. Immunol. 7:505-511.
-
(1995)
Curr. Opin. Immunol.
, vol.7
, pp. 505-511
-
-
Wynn, T.A.1
Cheever, A.W.2
-
9
-
-
0029142790
-
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection
-
Wynn, T.A., A.W. Cheever, D. Jankovic, R.W. Poindexter, P. Caspar, F.A. Lewis, and A. Sher. 1995. An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature. 376:594-596.
-
(1995)
Nature
, vol.376
, pp. 594-596
-
-
Wynn, T.A.1
Cheever, A.W.2
Jankovic, D.3
Poindexter, R.W.4
Caspar, P.5
Lewis, F.A.6
Sher, A.7
-
10
-
-
0028363023
-
Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis
-
Cheever, A.W., M.E. Williams, T.A. Wynn, F.D. Finkelman, R.A. Seder, T.M. Cox, S. Hieny, P. Caspar, and A. Sher. 1994. Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J. Immunol. 153:753-759.
-
(1994)
J. Immunol.
, vol.153
, pp. 753-759
-
-
Cheever, A.W.1
Williams, M.E.2
Wynn, T.A.3
Finkelman, F.D.4
Seder, R.A.5
Cox, T.M.6
Hieny, S.7
Caspar, P.8
Sher, A.9
-
11
-
-
0032697042
-
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
-
Chiaramonte, M.G., D.D. Donaldson, A.W. Cheever, and T.A. Wynn. 1999. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin. Invest. 104:777-785.
-
(1999)
J Clin. Invest.
, vol.104
, pp. 777-785
-
-
Chiaramonte, M.G.1
Donaldson, D.D.2
Cheever, A.W.3
Wynn, T.A.4
-
12
-
-
0034163317
-
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent
-
Fallon, P.G., E.J. Richardson, G.J. McKenzie, and A.N. McKenzie. 2000. Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent. J. Immunol. 164:2585-2591.
-
(2000)
J. Immunol.
, vol.164
, pp. 2585-2591
-
-
Fallon, P.G.1
Richardson, E.J.2
McKenzie, G.J.3
McKenzie, A.N.4
-
13
-
-
0029868565
-
Schistosoma mansoni in IL-4-deficient mice
-
Pearce, E.J., A. Cheever, S. Leonard, M. Covalesky, R. Fernandez-Botran, G. Kohler, and M. Kopf. 1996. Schistosoma mansoni in IL-4-deficient mice. Int. Immunol. 8:435-444.
-
(1996)
Int. Immunol.
, vol.8
, pp. 435-444
-
-
Pearce, E.J.1
Cheever, A.2
Leonard, S.3
Covalesky, M.4
Fernandez-Botran, R.5
Kohler, G.6
Kopf, M.7
-
14
-
-
0033168893
-
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile
-
Jankovic, D., M.C. Kullberg, N. Noben-Trauth, P. Caspar, J.M. Ward, A.W. Cheever, W.E. Paul, and A. Sher. 1999. Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J. Immunol. 163:337-342.
-
(1999)
J. Immunol.
, vol.163
, pp. 337-342
-
-
Jankovic, D.1
Kullberg, M.C.2
Noben-Trauth, N.3
Caspar, P.4
Ward, J.M.5
Cheever, A.W.6
Paul, W.E.7
Sher, A.8
-
15
-
-
0031573220
-
Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo
-
Wynn, T.A., R. Morawetz, T. Scharton-Kersten, S. Hieny, H.C. Morse, R. Kuhn, W. Muller, A.W. Cheever, and A. Sher. 1997. Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo. J. Immunol. 159:5014-5023.
-
(1997)
J. Immunol.
, vol.159
, pp. 5014-5023
-
-
Wynn, T.A.1
Morawetz, R.2
Scharton-Kersten, T.3
Hieny, S.4
Morse, H.C.5
Kuhn, R.6
Muller, W.7
Cheever, A.W.8
Sher, A.9
-
17
-
-
0032510452
-
A distinct role for interleukin-13 in Th2-cell-mediated immune responses
-
McKenzie, G.J., A. Bancroft, R.K. Grencis, and A.N. Mc-Kenzie. 1998. A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr. Biol. 8:339-342.
-
(1998)
Curr. Biol.
, vol.8
, pp. 339-342
-
-
McKenzie, G.J.1
Bancroft, A.2
Grencis, R.K.3
Mc-Kenzie, A.N.4
-
18
-
-
0032055579
-
A critical role for IL-13 in resistance to intestinal nematode infection
-
Bancroft, A.J., A.N. McKenzie, and R.K. Grencis. 1998. A critical role for IL-13 in resistance to intestinal nematode infection. J. Immunol. 160:3453-3461.
-
(1998)
J. Immunol.
, vol.160
, pp. 3453-3461
-
-
Bancroft, A.J.1
McKenzie, A.N.2
Grencis, R.K.3
-
19
-
-
0032007351
-
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
-
Urban, J.F., Jr., N. Noben-Trauth, D.D. Donaldson, K.B. Madden, S.C. Morris, M. Collins, and F.D. Finkelman. 1998. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity. 8:255-264.
-
(1998)
Immunity
, vol.8
, pp. 255-264
-
-
Urban J.F., Jr.1
Noben-Trauth, N.2
Donaldson, D.D.3
Madden, K.B.4
Morris, S.C.5
Collins, M.6
Finkelman, F.D.7
-
20
-
-
0034569025
-
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
-
Terabe, M., S. Matsui, N. Noben-Trauth, H. Chen, C. Watson, D.D. Donaldson, D.P. Carbone, W.E. Paul, and J.A. Berzofsky. 2000. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat. Immunol. 1:515-520.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 515-520
-
-
Terabe, M.1
Matsui, S.2
Noben-Trauth, N.3
Chen, H.4
Watson, C.5
Donaldson, D.D.6
Carbone, D.P.7
Paul, W.E.8
Berzofsky, J.A.9
-
21
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu, Z., R.J. Homer, Z. Wang, Q. Chen, G.P. Geba, J. Wang, Y. Zhang, and J.A. Elias. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779-788.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
22
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp, M., J. Luyimbazi, X. Xu, B. Schofield, T.Y. Neben, C.L. Karp, and D.D. Donaldson. 1998. Interleukin-13: central mediator of allergic asthma. Science. 282:2258-2261.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
23
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig, G., M. Warnock, A.E. Wakil, R. Venkayya, F. Brombacher, D.M. Rennick, D. Sheppard, M. Mohrs, D.D. Donaldson, R.M. Locksley, et al. 1998. Requirement for IL-13 independently of IL-4 in experimental asthma. Science. 282:2261-2263.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
Sheppard, D.7
Mohrs, M.8
Donaldson, D.D.9
Locksley, R.M.10
-
24
-
-
0027787877
-
Interleukin-2 receptor gamma chain: A functional component of the interleukin-4 receptor
-
Russell, S.M., A.D. Keegan, N. Harada, Y. Nakamura, M. Noguchi, P. Leland, M.C. Friedmann, A. Miyajima, R.K. Puri, W.E. Paul, et al. 1993. Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science. 262:1880-1883.
-
(1993)
Science
, vol.262
, pp. 1880-1883
-
-
Russell, S.M.1
Keegan, A.D.2
Harada, N.3
Nakamura, Y.4
Noguchi, M.5
Leland, P.6
Friedmann, M.C.7
Miyajima, A.8
Puri, R.K.9
Paul, W.E.10
-
25
-
-
0030068217
-
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
-
Hilton, D.J., J.G. Zhang, D. Metcalf, W.S. Alexander, N.A. Nicola, and T.A. Willson. 1996. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. USA. 93:497-501.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 497-501
-
-
Hilton, D.J.1
Zhang, J.G.2
Metcalf, D.3
Alexander, W.S.4
Nicola, N.A.5
Willson, T.A.6
-
26
-
-
0031015594
-
Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex
-
Miloux, B., P. Laurent, O. Bonnin, J. Lupker, D. Caput, N. Vita, and P. Ferrara. 1997. Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex. FEBS Lett. 401:163-166.
-
(1997)
FEBS Lett.
, vol.401
, pp. 163-166
-
-
Miloux, B.1
Laurent, P.2
Bonnin, O.3
Lupker, J.4
Caput, D.5
Vita, N.6
Ferrara, P.7
-
27
-
-
0033010373
-
The IL-4 receptor: Signaling mechanisms and biologic functions
-
Nelms, K., A.D. Keegan, J. Zamorano, J.J. Ryan, and W.E. Paul. 1999. The IL-4 receptor: signaling mechanisms and biologic functions. Annu. Rev. Immunol. 17:701-738.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
28
-
-
0029927153
-
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain
-
Caput, D., P. Laurent, M. Kaghad, J.M. Lelias, S. Lefort, N. Vita, and P. Ferrara. 1996. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain. J. Biol. Chem. 271:16921-16926.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16921-16926
-
-
Caput, D.1
Laurent, P.2
Kaghad, M.3
Lelias, J.M.4
Lefort, S.5
Vita, N.6
Ferrara, P.7
-
29
-
-
0032167603
-
The murine IL-13 receptor alpha 2: Molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1
-
Donaldson, D.D., M.J. Whitters, L.J. Fitz, T.Y. Neben, H. Finnerty, S.L. Henderson, R.M. O'Hara, Jr., D.R. Beier, K.J. Turner, C.R. Wood, et al. 1998. The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1. J. Immunol. 161:2317-2324.
-
(1998)
J. Immunol.
, vol.161
, pp. 2317-2324
-
-
Donaldson, D.D.1
Whitters, M.J.2
Fitz, L.J.3
Neben, T.Y.4
Finnerty, H.5
Henderson, S.L.6
O'Hara R.M., Jr.7
Beier, D.R.8
Turner, K.J.9
Wood, C.R.10
-
30
-
-
0035353154
-
The interleukin-13 receptor alpha2 chain: An essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway
-
Kawakami, K., J. Taguchi, T. Murata, and R.K. Puri. 2001. The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway. Blood. 97:2673-2679.
-
(2001)
Blood
, vol.97
, pp. 2673-2679
-
-
Kawakami, K.1
Taguchi, J.2
Murata, T.3
Puri, R.K.4
-
31
-
-
0032009864
-
Structure of and signal transduction through interleukin-4 and interleukin-13 receptors
-
Murata, T., N.I. Obiri, and R.K. Puri. 1998. Structure of and signal transduction through interleukin-4 and interleukin-13 receptors. Int. J. Mol. Med. 1:551-557.
-
(1998)
Int. J. Mol. Med.
, vol.1
, pp. 551-557
-
-
Murata, T.1
Obiri, N.I.2
Puri, R.K.3
-
32
-
-
0034804510
-
Expression of interleukin 13 receptor in glioma and renal cell carcinoma: IL13Ralpha2 as a decoy receptor for IL13
-
Bernard, J., D. Treton, C. Vermot-Desroches, C. Boden, P. Horellou, E. Angevin, P. Galanaud, J. Wijdenes, and Y. Richard. 2001. Expression of interleukin 13 receptor in glioma and renal cell carcinoma: IL13Ralpha2 as a decoy receptor for IL13. Lab. Invest. 81:1223-1231.
-
(2001)
Lab. Invest.
, vol.81
, pp. 1223-1231
-
-
Bernard, J.1
Treton, D.2
Vermot-Desroches, C.3
Boden, C.4
Horellou, P.5
Angevin, E.6
Galanaud, P.7
Wijdenes, J.8
Richard, Y.9
-
33
-
-
0031805083
-
The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: Overexpression of the nonsignaling interleukin-13 receptor alpha2
-
Feng, N., S.M. Lugli, B. Schnyder, J.F. Gauchat, P. Graber, E. Schlagenhauf, B. Schnarr, M. Wiederkehr-Adam, A. Duschl, M.H. Heim, et al. 1998. The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2. Lab. Invest. 78:591-602.
-
(1998)
Lab. Invest.
, vol.78
, pp. 591-602
-
-
Feng, N.1
Lugli, S.M.2
Schnyder, B.3
Gauchat, J.F.4
Graber, P.5
Schlagenhauf, E.6
Schnarr, B.7
Wiederkehr-Adam, M.8
Duschl, A.9
Heim, M.H.10
-
34
-
-
0027181936
-
Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
-
Colotta, F., F. Re, M. Muzio, R. Bertini, N. Polentarutti, M. Sironi, J.G. Giri, S.K. Dower, J.E. Sims, and A. Mantovani. 1993. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science. 261:472-475.
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
Re, F.2
Muzio, M.3
Bertini, R.4
Polentarutti, N.5
Sironi, M.6
Giri, J.G.7
Dower, S.K.8
Sims, J.E.9
Mantovani, A.10
-
35
-
-
0036085869
-
Effects of IL-13 on airway responses in the guinea pig
-
Morse, B., J.P. Sypek, D.D. Donaldson, K.J. Haley, and C.M. Lilly. 2002. Effects of IL-13 on airway responses in the guinea pig. Am. J. Physiol. Lung Cell. Mol. Physiol. 282:L44-L49.
-
(2002)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.282
-
-
Morse, B.1
Sypek, J.P.2
Donaldson, D.D.3
Haley, K.J.4
Lilly, C.M.5
-
36
-
-
0035888013
-
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity
-
Walter, D.M., J.J. McIntire, G. Berry, A.N. McKenzie, D.D. Donaldson, R.H. DeKruyff, and D.T. Umetsu. 2001. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J. Immunol. 167:4668-4675.
-
(2001)
J. Immunol.
, vol.167
, pp. 4668-4675
-
-
Walter, D.M.1
McIntire, J.J.2
Berry, G.3
McKenzie, A.N.4
Donaldson, D.D.5
DeKruyff, R.H.6
Umetsu, D.T.7
-
37
-
-
17944400239
-
IL-13-mediated worm expulsion is B7 independent and IFN-gamma sensitive
-
Urban, J., H. Fang, Q. Liu, M.J. Ekkens, S.J. Chen, D. Nguyen, V. Mitro, D.D. Donaldson, C. Byrd, R. Peach, et al. 2000. IL-13-mediated worm expulsion is B7 independent and IFN-gamma sensitive. J. Immunol. 164:4250-4256.
-
(2000)
J. Immunol.
, vol.164
, pp. 4250-4256
-
-
Urban, J.1
Fang, H.2
Liu, Q.3
Ekkens, M.J.4
Chen, S.J.5
Nguyen, D.6
Mitro, V.7
Donaldson, D.D.8
Byrd, C.9
Peach, R.10
-
38
-
-
0344091551
-
Enhanced IL-13 responses in mice lacking IL-13Rα
-
Wood, N., M. Whitters, B.A. Jacobson, J. Witek, J.P. Sypek, M. Kasaian, M. Eppihimer, M. Unger, S. Goldman, M. Collins, et al. 2003. Enhanced IL-13 responses in mice lacking IL-13Rα. J. Exp. Med. 197:703-709.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 703-709
-
-
Wood, N.1
Whitters, M.2
Jacobson, B.A.3
Witek, J.4
Sypek, J.P.5
Kasaian, M.6
Eppihimer, M.7
Unger, M.8
Goldman, S.9
Collins, M.10
-
39
-
-
0033566010
-
Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni
-
Hoffmann, K.F., S.L. James, A.W. Cheever, and T.A. Wynn. 1999. Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni. J. Immunol. 163:927-938.
-
(1999)
J. Immunol.
, vol.163
, pp. 927-938
-
-
Hoffmann, K.F.1
James, S.L.2
Cheever, A.W.3
Wynn, T.A.4
-
40
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan, M.H., U. Schindler, S.T. Smiley, and M.J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
41
-
-
0034492958
-
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease
-
Hesse, M., A.W. Cheever, D. Jankovic, and T.A. Wynn. 2000. NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am. J. Pathol. 157:945-955.
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 945-955
-
-
Hesse, M.1
Cheever, A.W.2
Jankovic, D.3
Wynn, T.A.4
-
42
-
-
0033555809
-
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
-
Chiaramonte, M.G., L.R. Schopf, T.Y. Neben, A.W. Cheever, D.D. Donaldson, and T.A. Wynn. 1999. IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J. Immunol. 162:920-930.
-
(1999)
J. Immunol.
, vol.162
, pp. 920-930
-
-
Chiaramonte, M.G.1
Schopf, L.R.2
Neben, T.Y.3
Cheever, A.W.4
Donaldson, D.D.5
Wynn, T.A.6
-
43
-
-
21544481657
-
Two improved and simplified methods for the spectrophotometric determination of hydroxyproline
-
Bergman, I., and R. Loxley. 1963. Two improved and simplified methods for the spectrophotometric determination of hydroxyproline. Anal. Biochem. 35:1961-1965.
-
(1963)
Anal. Biochem.
, vol.35
, pp. 1961-1965
-
-
Bergman, I.1
Loxley, R.2
-
44
-
-
0027260963
-
Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
-
Wynn, T.A., I. Eltoum, A.W. Cheever, F.A. Lewis, W.C. Gause, and A. Sher. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1430-1440.
-
(1993)
J. Immunol.
, vol.151
, pp. 1430-1440
-
-
Wynn, T.A.1
Eltoum, I.2
Cheever, A.W.3
Lewis, F.A.4
Gause, W.C.5
Sher, A.6
-
45
-
-
0032738991
-
Development of an assay to measure in vivo cytokine production in the mouse
-
Finkelman, F.D., and S.C. Morris. 1999. Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunol. 11:1811-1818.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1811-1818
-
-
Finkelman, F.D.1
Morris, S.C.2
-
46
-
-
0023640859
-
Variation of hepatic fibrosis and granuloma size among mouse strains infected with Schistosoma mansoni
-
Cheever, A.W., R.H. Duvall, T.A. Hallack, Jr., R.G. Minker, J.D. Malley, and K.G. Malley. 1987. Variation of hepatic fibrosis and granuloma size among mouse strains infected with Schistosoma mansoni. Am. J. Trop. Med. Hyg. 37:85-97.
-
(1987)
Am. J. Trop. Med. Hyg.
, vol.37
, pp. 85-97
-
-
Cheever, A.W.1
Duvall, R.H.2
Hallack T.A., Jr.3
Minker, R.G.4
Malley, J.D.5
Malley, K.G.6
-
47
-
-
0028231754
-
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
-
Wynn, T.A., I. Eltoum, I.P. Oswald, A.W. Cheever, and A. Sher. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551-1561.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1551-1561
-
-
Wynn, T.A.1
Eltoum, I.2
Oswald, I.P.3
Cheever, A.W.4
Sher, A.5
-
48
-
-
0030975719
-
Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains
-
Zhang, J.G., D.J. Hilton, T.A. Willson, C. McFarlane, B.A. Roberts, R.L. Moritz, R.J. Simpson, W.S. Alexander, D. Metcalf, and N.A. Nicola. 1997. Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains. J. Biol. Chem. 272:9474-9480.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9474-9480
-
-
Zhang, J.G.1
Hilton, D.J.2
Willson, T.A.3
McFarlane, C.4
Roberts, B.A.5
Moritz, R.L.6
Simpson, R.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
-
49
-
-
0026554818
-
Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice
-
Amiri, P., R.M. Locksley, T.G. Parslow, M. Sadick, E. Rector, D. Ritter, and J.H. McKerrow. 1992. Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice. Nature. 356:604-607.
-
(1992)
Nature
, vol.356
, pp. 604-607
-
-
Amiri, P.1
Locksley, R.M.2
Parslow, T.G.3
Sadick, M.4
Rector, E.5
Ritter, D.6
McKerrow, J.H.7
-
50
-
-
0032769614
-
Infection of mice lacking interleukin-7 (IL-7) reveals an unexpected role for IL-7 in the development of the parasite Schistosoma mansoni
-
Wolowczuk, I., S. Nutten, O. Roye, M. Delacre, M. Capron, R.M. Murray, F. Trottein, and C. Auriault. 1999. Infection of mice lacking interleukin-7 (IL-7) reveals an unexpected role for IL-7 in the development of the parasite Schistosoma mansoni. Infect. Immun. 67:4183-4190.
-
(1999)
Infect. Immun.
, vol.67
, pp. 4183-4190
-
-
Wolowczuk, I.1
Nutten, S.2
Roye, O.3
Delacre, M.4
Capron, M.5
Murray, R.M.6
Trottein, F.7
Auriault, C.8
-
51
-
-
0036679426
-
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling
-
Lanone, S., T. Zheng, Z. Zhu, W. Liu, C.G. Lee, B. Ma, Q. Chen, R.J. Homer, J. Wang, L.A. Rabach, et al. 2002. Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J. Clin. Invest. 110:463-474.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 463-474
-
-
Lanone, S.1
Zheng, T.2
Zhu, Z.3
Liu, W.4
Lee, C.G.5
Ma, B.6
Chen, Q.7
Homer, R.J.8
Wang, J.9
Rabach, L.A.10
-
52
-
-
0036551274
-
Activation of hepatic stellate cells-a key issue in liver fibrosis
-
Reeves, H.L., and S.L. Friedman. 2002. Activation of hepatic stellate cells-a key issue in liver fibrosis. Front. Biosci. 7:d808-d826.
-
(2002)
Front. Biosci.
, vol.7
-
-
Reeves, H.L.1
Friedman, S.L.2
-
53
-
-
0035576207
-
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
-
Hesse, M., M. Modolell, A.C. La Flamme, M. Schito, J.M. Fuentes, A.W. Cheever, E.J. Pearce, and T.A. Wynn. 2001. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J. Immunol. 167:6533-6544.
-
(2001)
J. Immunol.
, vol.167
, pp. 6533-6544
-
-
Hesse, M.1
Modolell, M.2
La Flamme, A.C.3
Schito, M.4
Fuentes, J.M.5
Cheever, A.W.6
Pearce, E.J.7
Wynn, T.A.8
-
54
-
-
0028916297
-
Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines
-
Modolell, M., I.M. Corraliza, F. Link, G. Soler, and K. Eichmann. 1995. Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines. Eur. J. Immunol. 25:1101-1104.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1101-1104
-
-
Modolell, M.1
Corraliza, I.M.2
Link, F.3
Soler, G.4
Eichmann, K.5
-
55
-
-
0032519993
-
Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response
-
Kaplan, M.H., J.R. Whitfield, D.L. Boros, and M.J. Grusby. 1998. Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J. Immunol. 160:1850-1856.
-
(1998)
J. Immunol.
, vol.160
, pp. 1850-1856
-
-
Kaplan, M.H.1
Whitfield, J.R.2
Boros, D.L.3
Grusby, M.J.4
-
56
-
-
0030776426
-
Advanced multiplexed analysis with the FlowMetrix system
-
Fulton, R.J., R.L. McDade, P.L. Smith, L.J. Kienker, and J.R. Kettman, Jr. 1997. Advanced multiplexed analysis with the FlowMetrix system. Clin. Chem. 43:1749-1756.
-
(1997)
Clin. Chem.
, vol.43
, pp. 1749-1756
-
-
Fulton, R.J.1
McDade, R.L.2
Smith, P.L.3
Kienker, L.J.4
Kettman J.R., Jr.5
-
57
-
-
0023879839
-
Recombinant human interleukin 5 is a selective activator of human eosinophil function
-
Lopez, A.F., C.J. Sanderson, J.R. Gamble, H.D. Campbell, I.G. Young, and M.A. Vadas. 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219-224.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 219-224
-
-
Lopez, A.F.1
Sanderson, C.J.2
Gamble, J.R.3
Campbell, H.D.4
Young, I.G.5
Vadas, M.A.6
-
58
-
-
0035903306
-
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β(1)
-
Lee, C.G., R.J. Homer, Z. Zhu, S. Lanone, X. Wang, V. Koteliansky, J.M. Shipley, P. Gotwals, P. Noble, Q. Chen, et al. 2001. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β(1). J. Exp. Med. 194:809-821.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 809-821
-
-
Lee, C.G.1
Homer, R.J.2
Zhu, Z.3
Lanone, S.4
Wang, X.5
Koteliansky, V.6
Shipley, J.M.7
Gotwals, P.8
Noble, P.9
Chen, Q.10
-
59
-
-
0025924547
-
Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni
-
Grzych, J.M., E.J. Pearce, A. Cheever, Z.A. Caulada, P. Caspar, S. Heiny, F. Lewis, and A. Sher. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J. Immunol. 146:1322-1327.
-
(1991)
J. Immunol.
, vol.146
, pp. 1322-1327
-
-
Grzych, J.M.1
Pearce, E.J.2
Cheever, A.3
Caulada, Z.A.4
Caspar, P.5
Heiny, S.6
Lewis, F.7
Sher, A.8
-
60
-
-
0031570939
-
IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis
-
Brunet, L.R., F.D. Finkelman, A.W. Cheever, M.A. Kopf, and E.J. Pearce. 1997. IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis. J. Immunol. 159:777-785.
-
(1997)
J. Immunol.
, vol.159
, pp. 777-785
-
-
Brunet, L.R.1
Finkelman, F.D.2
Cheever, A.W.3
Kopf, M.A.4
Pearce, E.J.5
-
61
-
-
0033984466
-
Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice
-
Fallon, P.G., E.J. Richardson, P. Smith, and D.W. Dunne. 2000. Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice. Eur. J. Immunol. 30:470-480.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 470-480
-
-
Fallon, P.G.1
Richardson, E.J.2
Smith, P.3
Dunne, D.W.4
-
62
-
-
0037155828
-
A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha-2 and their rapid mobilization by interferon-gamma
-
Daines, M.O., and G.K. Hershey. 2002. A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha-2 and their rapid mobilization by interferon-gamma. J. Biol. Chem. 277:10387-10393.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10387-10393
-
-
Daines, M.O.1
Hershey, G.K.2
-
63
-
-
0035495857
-
The germ-less theory of allergic disease: Revisiting the hygiene hypothesis
-
Wills-Karp, M., J. Santeliz, and C.L. Karp. 2001. The germ-less theory of allergic disease: revisiting the hygiene hypothesis. Nat. Rev. Immunol. 1:69-75.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 69-75
-
-
Wills-Karp, M.1
Santeliz, J.2
Karp, C.L.3
-
64
-
-
0014275786
-
Experimental production of bilharzial pipe-stem fibrosis in the chimpanzee
-
Von Lichtenberg, F., and E.H. Sadun. 1968. Experimental production of bilharzial pipe-stem fibrosis in the chimpanzee. Exp. Parasitol. 22:264-278.
-
(1968)
Exp. Parasitol.
, vol.22
, pp. 264-278
-
-
Von Lichtenberg, F.1
Sadun, E.H.2
-
65
-
-
0035892755
-
Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: New insight into the role of tissue inhibitors of matrix metalloproteinases
-
Vaillant, B., M.G. Chiaramonte, A.W. Cheever, P.D. Soloway, and T.A. Wynn. 2001. Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: new insight into the role of tissue inhibitors of matrix metalloproteinases. J. Immunol. 167:7017-7026.
-
(2001)
J. Immunol.
, vol.167
, pp. 7017-7026
-
-
Vaillant, B.1
Chiaramonte, M.G.2
Cheever, A.W.3
Soloway, P.D.4
Wynn, T.A.5
-
66
-
-
0027239843
-
Anticytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokineanti-cytokine antibody complexes
-
Finkelman, F.D., K.B. Madden, S.C. Morris, J.M. Holmes, N. Boiani, I.M. Katona, and C.R. Maliszewski. 1993. Anticytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokineanti-cytokine antibody complexes. J. Immunol. 151:1235-1244.
-
(1993)
J. Immunol.
, vol.151
, pp. 1235-1244
-
-
Finkelman, F.D.1
Madden, K.B.2
Morris, S.C.3
Holmes, J.M.4
Boiani, N.5
Katona, I.M.6
Maliszewski, C.R.7
-
67
-
-
0032824790
-
Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis: A quantitative study of open lung biopsies
-
Majumdar, S., D. Li, T. Ansari, P. Pantelidis, C.M. Black, M. Gizycki, R.M. du Bois, and P.K. Jeffery. 1999. Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis: a quantitative study of open lung biopsies. Eur. Respir. J. 14:251-257.
-
(1999)
Eur. Respir. J.
, vol.14
, pp. 251-257
-
-
Majumdar, S.1
Li, D.2
Ansari, T.3
Pantelidis, P.4
Black, C.M.5
Gizycki, M.6
Du Bois, R.M.7
Jeffery, P.K.8
-
68
-
-
0029113474
-
A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)
-
Wallace, W.A., E.A. Ramage, D. Lamb, and S.E. Howie. 1995. A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA). Clin. Exp. Immunol. 101:436-441.
-
(1995)
Clin. Exp. Immunol.
, vol.101
, pp. 436-441
-
-
Wallace, W.A.1
Ramage, E.A.2
Lamb, D.3
Howie, S.E.4
-
69
-
-
0033610271
-
Chronic allograft rejection. Do the Th2 cells preferentially induced by indirect alloantigen recognition play a dominant role?
-
Shirwan, H. 1999. Chronic allograft rejection. Do the Th2 cells preferentially induced by indirect alloantigen recognition play a dominant role? Transplantation. 68:715-726.
-
(1999)
Transplantation
, vol.68
, pp. 715-726
-
-
Shirwan, H.1
-
70
-
-
0027451925
-
PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis
-
Baecher-Allan, C.M., and R.K. Barth. 1993. PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis. Reg. Immunol. 5:207-217.
-
(1993)
Reg. Immunol.
, vol.5
, pp. 207-217
-
-
Baecher-Allan, C.M.1
Barth, R.K.2
-
71
-
-
0031056613
-
Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis
-
Hasegawa, M., M. Fujimoto, K. Kikuchi, and K. Takehara. 1997. Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis. J. Rheumatol. 24:328-332.
-
(1997)
J. Rheumatol.
, vol.24
, pp. 328-332
-
-
Hasegawa, M.1
Fujimoto, M.2
Kikuchi, K.3
Takehara, K.4
-
72
-
-
0033053344
-
Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat
-
Westermann, W., R. Schobl, E.P. Rieber, and K.H. Frank. 1999. Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat. Int. J. Radiat. Biol. 75:629-638.
-
(1999)
Int. J. Radiat. Biol.
, vol.75
, pp. 629-638
-
-
Westermann, W.1
Schobl, R.2
Rieber, E.P.3
Frank, K.H.4
-
73
-
-
0030885185
-
Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses
-
Shi, Z., A.E. Wakil, and D.C. Rockey. 1997. Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses. Proc. Natl. Acad. Sci. USA. 94:10663-10668.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10663-10668
-
-
Shi, Z.1
Wakil, A.E.2
Rockey, D.C.3
|