Modified siRNA structure with a single nucleotide bulge overcomes conventional sirna-mediated off-target silencing

Molecular Therapy

Volumn 19, Issue 9, 2011, Pages 1676-1687

  Dua, Pooja ^a,b   Yoo, Jae Wook ^a   Kim, Soyoun ^b   Lee, Dong Ki ^a  

^a Sungkyunkwan University   (South Korea)

^b Dongguk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; SMALL INTERFERING RNA; SURVIVIN;

ANTISENSE VECTOR; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; GENE FUNCTION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; RNA INTERFERENCE; RNA STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; THERMODYNAMICS;

EID: 80052393683     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.109     Document Type: Article

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