A cell-permeable phosphine-borane complex delays retinal ganglion cell death after axonal injury through activation of the pro-survival extracellular signal-regulated kinases 1/2 pathway

Journal of Neurochemistry

Volumn 118, Issue 6, 2011, Pages 1075-1086

  Almasieh, Mohammadali ^a   Lieven, Christopher J ^b   Levin, Leonard A ^b,c   Di Polo, Adriana ^a,c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MONTREAL   (Canada)

Author keywords

brain derived neurotrophic factor; extracellular signal regulated kinase 1 2; neuroprotection; redox signaling; retinal ganglion cell; superoxide

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; BIS(3 PROPIONIC ACID METHYL ESTER)PHENYLPHOSPHINE BORATE COMPLEX 1; BORIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; GLAUCOMA; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL;

ANIMALS; AXONS; AXOTOMY; BLOTTING, WESTERN; BORANES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENTS; OCULAR HYPERTENSION; OPTIC NERVE INJURIES; PHOSPHINES; RATS; RATS, SPRAGUE-DAWLEY; REDUCING AGENTS; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; SUPEROXIDES;

RATTUS;

EID: 80052388066     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07382.x     Document Type: Article

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