Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells

Experimental Eye Research

Volumn 83, Issue 5, 2006, Pages 1252-1259

  Schlieve, Christopher R ^a   Tam, Annie ^b   Nilsson, Bradley L ^b   Lieven, Christopher J ^a   Raines, Ronald T ^b   Levin, Leonard A ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

intracellular signaling; neuroprotection; optic nerve; oxidation reduction; redox; retinal ganglion cells; tris(2 carboxyethyl)phosphine

Indexed keywords

(3 PROPIONIC ACID METHYL ESTER)DIPHENYLPHOSPHINE; 4',6 DIAMIDINO 2 PHENYLINDOLE; BIS(3 PROPIONIC ACID METHYL ESTER)PHENYLPHOSPHINE; CALCEIN; PHOSPHINE DERIVATIVE; POLYLYSINE; REDUCING AGENT; THIOL DERIVATIVE; TRIS(2 CARBOXYETHYL)PHOSPHINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME STABILITY; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; OXIDATION; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; STAINING; TIME; TISSUE CULTURE;

ANIMALS; APOPTOSIS; BORANES; CELL COUNT; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; INDICATORS AND REAGENTS; NEUROPROTECTIVE AGENTS; OPTIC NERVE; OXIDATION-REDUCTION; PHOSPHINES; RATS; RATS, LONG-EVANS; REDUCING AGENTS; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

EID: 33748711827     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2006.07.002     Document Type: Article

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