Inter-domain communication mechanisms in an ABC importer: A molecular dynamics study of the MalFGK2E complex

PLoS Computational Biology

Volumn 7, Issue 8, 2011, Pages

  Oliveira, A Sofia F ^a   Baptista, António M ^a   Soares, Cláudio M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; BIOLOGICAL MEMBRANES; DIMERS; ESCHERICHIA COLI; HYDROLYSIS; PROTEINS;

ATP HYDROLYSIS; COMMUNICATION MECHANISMS; CONFORMATIONAL CHANGE; DYNAMIC STUDIES; ENERGY; INORGANIC PHOSPHATES; INTERDOMAIN COMMUNICATION; SUBDOMAIN; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE DOMAIN;

MOLECULAR DYNAMICS;

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CARRIER PROTEINS AND BINDING PROTEINS; MALTOSE; PHOSPHATE; PROTEIN MALE; PROTEIN MALF; PROTEIN MALG; PROTEIN MALK2; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; MALTOSE TRANSPORT SYSTEM, E COLI;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ESCHERICHIA COLI; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE BINDING SITE; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIMULATION; STRUCTURE ANALYSIS; CHEMISTRY; HYDROLYSIS; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ATP-BINDING CASSETTE TRANSPORTERS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI PROTEINS; HYDROLYSIS; MALTOSE; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 80052311546     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002128     Document Type: Article

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