Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter

Structure

Volumn 9, Issue 7, 2001, Pages 571-586

  Karpowich, Nathan ^a   Martsinkevich, Oksana ^a   Millen, Linda ^b   Yuan, Yu Ren ^a   Dai, Peter L ^a   MacVey, Karen ^b   Thomas, Philip J ^b   Hunt, John F ^a  

^a MC2434 Columbia University ^*  (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

ABC transporter; ATPase; Induced fit; Mechanochemistry; Protein crystallography; Transmembrane transport

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ATP BINDING CASETTE TRANSPORTER; CARRIER PROTEIN; GLUTAMINE; HISTIDINE; MAGNESIUM; PHOSPHATE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CHEMICAL BINDING; CRYSTAL STRUCTURE; HYDROLYSIS; MEMBRANE TRANSPORT; METHANOCOCCUS JANNASCHII; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; STRUCTURE ANALYSIS;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; AMINO ACID TRANSPORT SYSTEMS, BASIC; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; MAGNESIUM; MEMBRANE TRANSPORT PROTEINS; METHANOCOCCUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; PHYLOGENY; PROTEIN CONFORMATION;

METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS;

EID: 0034941969     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00617-7     Document Type: Article

References (63)

1. Microbial genome analyses: Global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities
2. Getting in or out: Early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters
3. Families of transmembrane transporters selective for amino acids and their derivatives
4. ABC transporters: From microorganisms to man
5. P-glycoprotein and multidrug resistance
6. The Escherichia coli ATP-binding cassette (ABC) proteins
7. An inventory of the human ABC proteins
8. Saccharomyces cerevisiae ABC proteins and their relevance to human health and disease
9. Protein exporter function and in vitro ATPase activity are correlated in ABC-domain mutants of HlyB
10. The ABC of channel regulation
11. ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR
12. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
13. Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters
14. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome
15. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy
16. Crystal structure of the ATP-binding subunit of an ABC transporter
17. Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon thermococcus litoralis
18. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
19. A bacterial system for investigating transport effects of cystic fibrosis-associated mutations
20. Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii
21. The crystal structure of the MJ0796 ATP-binding cassette: Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter
22. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation
23. Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubility, dimerization, and ATPase activity
24. The ATP-binding cassette (ABC) transporter for maltose/maltodextrins of Salmonella typhimurium. Characterization of the ATPase activity associated with the purified MalK subunit
25. The ATP-binding cassette subunit of the maltose transporter MalK antagonizes MalT, the activator of the Escherichia coli mal regulon
26. Nucleotide-induced conformational changes of MalK, a bacterial ATP binding cassette transporter protein
27. Molecular and biochemical analysis of MalK, the ATP-hydrolyzing subunit of the trehalose/maltose transport system of the hyperthermophilic archaeon Thermococcus litoralis
28. The complete genome of the hyperthermophilic bacterium Aquifex aeolicus
29. MalFGK complex assembly and transport and regulatory characteristics of MalK insertion mutants
30. Structure at 2.8 Å resolution of F1-ATPase from bovine heart mitochondria
31. A common topology of proteins catalyzing ATP-triggered reactions
32. Structure of the recA protein-ADP complex
33. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
34. Structural model of the nucleotide-binding conserved component of periplasmic permeases
35. A putative helical domain in the MalK subunit of the ATP-binding-cassette transport system for maltose of Salmonella typhimurium (MalFGK2) is crucial for interaction with MalF and MalG. A study using the LacK protein of Agrobacterium radiobacter as a tool
36. Subunit interactions in ABC transporters: A conserved sequence in hydrophobic membrane proteins of periplasmic permeases defines an important site of interaction with the ATPase subunits
37. Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains
38. In vitro interaction between components of the inner membrane complex of the maltose ABC transporter of Escherichia coli: Modulation by ATP
39. Maltose transport in Escherichia coli: Mutations that uncouple ATP hydrolysis from transport
40. Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK
41. Novel missense mutations that affect the transport function of MalK, the ATP-binding-cassette subunit of the Salmonella enterica serovar typhimurium maltose transport system
42. ATP modulates subunit-subunit interactions in an ATP-binding cassette transporter (MalFGK2) determined by site-directed chemical cross-linking
43. One intact ATP-binding subunit is sufficient to support ATP hydrolysis and translocation in an ABC transporter, the histidine permease
44. Modulation of ATPase activity by physical disengagement of the ATP-binding domains of an ABC transporter, the histidine permease
45. Characterization, localization and transmembrane organization of the three proteins PrtD, PrtE and PrtF necessary for protease secretion by the gram-negative bacterium Erwinia chrysanthemi
46. The structural basis of the myosin ATPase activity
47. The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex
48. Vanadate and bafilomycin A1 are potent inhibitors of the ATPase activity of the reconstituted bacterial ATP-binding cassette transporter for maltose (MalFGK2)
49. Processing of X-ray diffraction data collected in oscillation mode
50. Maximum-likelihood heavy-atom parameter refinement in the MIR and MAD methods
51. Methods used in the structure determination of bovine mitochondrial F1 ATPase
52. The CCP4 (Collaborative Computational Project Number 4) suite: Programs for protein crystallography
53. AMoRe: An automated package for molecular replacement
54. Improved methods for building protein models in electron density maps and the location of errors in these models
55. Accurate bond and angle parameters for X-ray protein structure refinement
56. Molscript: A program to produce both detailed and schematic plots of proteins
57. Raster3D photorealistic molecular graphics
58. Beta-turns and their distortions: A proposed new nomenclature
59. Free R value: A novel statistical quantity for assessing the accuracy of crystal structures
60. Procheck: A program to check the stereochemical quality of protein structures