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Volumn 3, Issue 4, 2011, Pages 255-266

Biological activities and health benefit effects of natural pigments derived from marine algae

Author keywords

Anti inflammatory; Anticancer; Antioxidant; Marine algae; Natural pigments

Indexed keywords

ALGAE;

EID: 80052267548     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2011.07.001     Document Type: Review
Times cited : (434)

References (118)
  • 2
    • 73349138274 scopus 로고    scopus 로고
    • The effects of Xanthigen™ in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat
    • Abidov M., Ramazanov Z., Seifulla R., Grachev S. The effects of Xanthigen™ in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat. Diabetes, Obesity and Metabolism 2010, 12:72-81.
    • (2010) Diabetes, Obesity and Metabolism , vol.12 , pp. 72-81
    • Abidov, M.1    Ramazanov, Z.2    Seifulla, R.3    Grachev, S.4
  • 4
    • 0842304213 scopus 로고    scopus 로고
    • Biotransformation of fucoxanthinol into amarouxanthin a in mice and hepG2 cells: formation and cytotoxicity of fucoxanthin metabolites I
    • Asai A., Sugawara T., Ono H., Nagao A. Biotransformation of fucoxanthinol into amarouxanthin a in mice and hepG2 cells: formation and cytotoxicity of fucoxanthin metabolites I. Drug Metabolism and Disposition 2004, 32:205-211.
    • (2004) Drug Metabolism and Disposition , vol.32 , pp. 205-211
    • Asai, A.1    Sugawara, T.2    Ono, H.3    Nagao, A.4
  • 5
    • 0034843457 scopus 로고    scopus 로고
    • New strategies for the treatment of Parkinson's disease hold considerable promise for the future management of neurodegenerative disorders
    • Bjarkam C.R., Sørensen J.C., Sunde N.Å., Geneser F.A., Østergaard K. New strategies for the treatment of Parkinson's disease hold considerable promise for the future management of neurodegenerative disorders. Biogerontology 2001, 2:193-207.
    • (2001) Biogerontology , vol.2 , pp. 193-207
    • Bjarkam, C.R.1    Sørensen, J.C.2    Sunde, N.Å.3    Geneser, F.A.4    Østergaard, K.5
  • 6
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • Block M., Zecca L., Hong J. Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms. Nature Reviews Neuroscience 2007, 8:57-69.
    • (2007) Nature Reviews Neuroscience , vol.8 , pp. 57-69
    • Block, M.1    Zecca, L.2    Hong, J.3
  • 7
    • 0000979294 scopus 로고
    • Phycobiliproteins and complementary chromatic adaptation
    • Bogorad L. Phycobiliproteins and complementary chromatic adaptation. Annual Review of Plant Physiology 1975, 26:369-401.
    • (1975) Annual Review of Plant Physiology , vol.26 , pp. 369-401
    • Bogorad, L.1
  • 8
    • 68549133536 scopus 로고    scopus 로고
    • Bioavailability of non-provitamin A carotenoids
    • Bohn T. Bioavailability of non-provitamin A carotenoids. Current Nutrition and Food Science 2008, 4:240-258.
    • (2008) Current Nutrition and Food Science , vol.4 , pp. 240-258
    • Bohn, T.1
  • 11
    • 84950792123 scopus 로고
    • Pyropheophytin a as an antioxidative substance from the marine alga, arame (Eisenia bicyclis)
    • Cahyana A.H., Shuto Y., Kinoshita Y. Pyropheophytin a as an antioxidative substance from the marine alga, arame (Eisenia bicyclis). Bioscience, Biotechnology, and Biochemistry 1992, 56:1533-1535.
    • (1992) Bioscience, Biotechnology, and Biochemistry , vol.56 , pp. 1533-1535
    • Cahyana, A.H.1    Shuto, Y.2    Kinoshita, Y.3
  • 12
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nature Medicine 2003, 9:653-660.
    • (2003) Nature Medicine , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 13
    • 79952535796 scopus 로고    scopus 로고
    • Antioxidant properties of extract and fractions from Enteromorpha prolifera, a type of green seaweed
    • Cho M.L., Lee H.S., Kang I.J., Won M.H., You S.G. Antioxidant properties of extract and fractions from Enteromorpha prolifera, a type of green seaweed. Food Chemistry 2011, 127:999-1006.
    • (2011) Food Chemistry , vol.127 , pp. 999-1006
    • Cho, M.L.1    Lee, H.S.2    Kang, I.J.3    Won, M.H.4    You, S.G.5
  • 14
    • 80051791196 scopus 로고    scopus 로고
    • Antioxidants from macroalgae: Potential applications in human health and nutrition
    • Cornish M., Garbary D. Antioxidants from macroalgae: Potential applications in human health and nutrition. Algae 2010, 25:155-171.
    • (2010) Algae , vol.25 , pp. 155-171
    • Cornish, M.1    Garbary, D.2
  • 15
    • 33644826101 scopus 로고    scopus 로고
    • Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin
    • Curat C., Wegner V., Sengenes C., Miranville A., Tonus C., Busse R., et al. Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 2006, 49:744-747.
    • (2006) Diabetologia , vol.49 , pp. 744-747
    • Curat, C.1    Wegner, V.2    Sengenes, C.3    Miranville, A.4    Tonus, C.5    Busse, R.6
  • 16
    • 77952615626 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis in osteoclast-like cells differentiated from RAW264.7 cells
    • Das S.K., Ren R., Hashimoto T., Kanazawa K. Fucoxanthin induces apoptosis in osteoclast-like cells differentiated from RAW264.7 cells. Journal of Agricultural and Food Chemistry 2010, 58:6090-6095.
    • (2010) Journal of Agricultural and Food Chemistry , vol.58 , pp. 6090-6095
    • Das, S.K.1    Ren, R.2    Hashimoto, T.3    Kanazawa, K.4
  • 17
    • 0034186155 scopus 로고    scopus 로고
    • Natural pigments: Carotenoids, anthocyanins, and betalains-Characteristics, biosynthesis, processing, and stability
    • Delgado-Vargas F., Jiménez A., Paredes-López O. Natural pigments: Carotenoids, anthocyanins, and betalains-Characteristics, biosynthesis, processing, and stability. Critical Reviews in Food Science and Nutrition 2000, 40:173-289.
    • (2000) Critical Reviews in Food Science and Nutrition , vol.40 , pp. 173-289
    • Delgado-Vargas, F.1    Jiménez, A.2    Paredes-López, O.3
  • 18
    • 0022131677 scopus 로고
    • Antioxidant effects of chlorophyll and pheophytin on the autoxidation of oils in the dark. I. Comparison of the inhibitory effects
    • Endo Y., Usuki R., Kaneda T. Antioxidant effects of chlorophyll and pheophytin on the autoxidation of oils in the dark. I. Comparison of the inhibitory effects. Journal of the American Oil Chemists' Society 1985, 62:1375-1378.
    • (1985) Journal of the American Oil Chemists' Society , vol.62 , pp. 1375-1378
    • Endo, Y.1    Usuki, R.2    Kaneda, T.3
  • 19
    • 0022130450 scopus 로고
    • Antioxidant effects of chlorophyll and pheophytin on the autoxidation of oils in the dark. II. The mechanism of antioxidative action of chlorophyll
    • Endo Y., Usuki R., Kaneda T. Antioxidant effects of chlorophyll and pheophytin on the autoxidation of oils in the dark. II. The mechanism of antioxidative action of chlorophyll. Journal of the American Oil Chemists' Society 1985, 62:1387-1390.
    • (1985) Journal of the American Oil Chemists' Society , vol.62 , pp. 1387-1390
    • Endo, Y.1    Usuki, R.2    Kaneda, T.3
  • 20
    • 33846576700 scopus 로고    scopus 로고
    • Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives
    • Ferruzzi M.G., Blakeslee J. Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives. Nutrition Research 2007, 27:1-12.
    • (2007) Nutrition Research , vol.27 , pp. 1-12
    • Ferruzzi, M.G.1    Blakeslee, J.2
  • 21
  • 23
    • 0001493040 scopus 로고
    • Phycobiliproteins-A family of valuable, widely used fluorophores
    • Glazer A.N. Phycobiliproteins-A family of valuable, widely used fluorophores. Journal of Applied Phycology 1994, 6:105-112.
    • (1994) Journal of Applied Phycology , vol.6 , pp. 105-112
    • Glazer, A.N.1
  • 24
    • 69849088549 scopus 로고    scopus 로고
    • The distribution and accumulation of fucoxanthin and its metabolites after oral administration in mice
    • Hashimoto T., Ozaki Y., Taminato M., Das S., Mizuno M., Yoshimura K., et al. The distribution and accumulation of fucoxanthin and its metabolites after oral administration in mice. British Journal of Nutrition 2009, 102:242-248.
    • (2009) British Journal of Nutrition , vol.102 , pp. 242-248
    • Hashimoto, T.1    Ozaki, Y.2    Taminato, M.3    Das, S.4    Mizuno, M.5    Yoshimura, K.6
  • 26
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M. The biochemistry of apoptosis. Nature 2000, 407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.1
  • 27
    • 67449116102 scopus 로고    scopus 로고
    • Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent α-glucosidase and α-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice
    • Heo S.J., Hwang J.Y., Choi J.I., Han J.S., Kim H.J., Jeon Y.J. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent α-glucosidase and α-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. European Journal of Pharmacology 2009, 615:252-256.
    • (2009) European Journal of Pharmacology , vol.615 , pp. 252-256
    • Heo, S.J.1    Hwang, J.Y.2    Choi, J.I.3    Han, J.S.4    Kim, H.J.5    Jeon, Y.J.6
  • 28
    • 64149125149 scopus 로고    scopus 로고
    • Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage
    • Heo S., Jeon Y. Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage. Journal of Photochemistry and Photobiology B: Biology 2009, 95:101-107.
    • (2009) Journal of Photochemistry and Photobiology B: Biology , vol.95 , pp. 101-107
    • Heo, S.1    Jeon, Y.2
  • 29
    • 54249096899 scopus 로고    scopus 로고
    • Cytoprotective effect of fucoxanthin isolated from brown algae Sargassum siliquastrum against H2O2-induced cell damage
    • Heo S., Ko S., Kang S., Kang H., Kim J., Kim S., et al. Cytoprotective effect of fucoxanthin isolated from brown algae Sargassum siliquastrum against H2O2-induced cell damage. European Food Research and Technology A 2008, 228:145-151.
    • (2008) European Food Research and Technology A , vol.228 , pp. 145-151
    • Heo, S.1    Ko, S.2    Kang, S.3    Kang, H.4    Kim, J.5    Kim, S.6
  • 30
    • 77955052543 scopus 로고    scopus 로고
    • Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages
    • Heo S.J., Yoon W.J., Kim K.N., Ahn G.N., Kang S.M., Kang D.H., et al. Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology 2010, 48:2045-2051.
    • (2010) Food and Chemical Toxicology , vol.48 , pp. 2045-2051
    • Heo, S.J.1    Yoon, W.J.2    Kim, K.N.3    Ahn, G.N.4    Kang, S.M.5    Kang, D.H.6
  • 31
    • 0033011445 scopus 로고    scopus 로고
    • Potent suppressive effect of a Japanese edible seaweed, Enteromorpha prolifera (Sujiao-nori) on initiation and promotion phases of chemically induced mouse skin tumorigenesis
    • Hiqashi Okai K., Otani S., Okai Y. Potent suppressive effect of a Japanese edible seaweed, Enteromorpha prolifera (Sujiao-nori) on initiation and promotion phases of chemically induced mouse skin tumorigenesis. Cancer Letters 1999, 140:21-25.
    • (1999) Cancer Letters , vol.140 , pp. 21-25
    • Hiqashi Okai, K.1    Otani, S.2    Okai, Y.3
  • 32
    • 79958758613 scopus 로고    scopus 로고
    • Bioactive compounds in seaweed: Functional food applications and legislation
    • Holdt S.L., Kraan S. Bioactive compounds in seaweed: Functional food applications and legislation. Journal of Applied Phycology 2011, 23:543-597.
    • (2011) Journal of Applied Phycology , vol.23 , pp. 543-597
    • Holdt, S.L.1    Kraan, S.2
  • 33
    • 80052268175 scopus 로고    scopus 로고
    • Fucose complexes, fucoxanthin, fucoid and fat storage. Townsend letter.
    • Holt, S. (2008). Fucose complexes, fucoxanthin, fucoid and fat storage (pp. 87-92). Townsend letter.
    • (2008) , pp. 87-92
    • Holt, S.1
  • 38
    • 33846479936 scopus 로고    scopus 로고
    • Pheophytin a, a low molecular weight compound found in the marine brown alga Sargassum fulvellum, promotes the differentiation of PC12 cells
    • Ina A., Hayashi K., Nozaki H., Kamei Y. Pheophytin a, a low molecular weight compound found in the marine brown alga Sargassum fulvellum, promotes the differentiation of PC12 cells. International Journal of Developmental Neuroscience 2007, 25:63-68.
    • (2007) International Journal of Developmental Neuroscience , vol.25 , pp. 63-68
    • Ina, A.1    Hayashi, K.2    Nozaki, H.3    Kamei, Y.4
  • 39
    • 34247643893 scopus 로고    scopus 로고
    • Vitamin B 12, a chlorophyll-related analog to pheophytin a from marine brown algae, promotes neurite outgrowth and stimulates differentiation in PC12 cells
    • Ina A., Kamei Y. Vitamin B 12, a chlorophyll-related analog to pheophytin a from marine brown algae, promotes neurite outgrowth and stimulates differentiation in PC12 cells. Cytotechnology 2006, 52:181-187.
    • (2006) Cytotechnology , vol.52 , pp. 181-187
    • Ina, A.1    Kamei, Y.2
  • 40
    • 80052268430 scopus 로고    scopus 로고
    • The Asia-Pacific perspective: Redefining obesity and its treatment. Health Communications Australia Pty Limited on behalf of the Steering Committee.
    • Inoue, S., Zimmet, P., Caterson, I., Chunming, C., Ikeda, Y., Khalid, A., Kim, Y., & Bassett, J. (2000). The Asia-Pacific perspective: Redefining obesity and its treatment (pp. 1-55). Health Communications Australia Pty Limited on behalf of the Steering Committee.
    • (2000) , pp. 1-55
    • Inoue, S.1    Zimmet, P.2    Caterson, I.3    Chunming, C.4    Ikeda, Y.5    Khalid, A.6    Kim, Y.7    Bassett, J.8
  • 41
    • 84919971620 scopus 로고    scopus 로고
    • Natural products from seaweeds. In Plant-derived natural products. Springer-Verlag New York Inc.
    • Ioannou, E., & Roussis, V. (2009). Natural products from seaweeds. In Plant-derived natural products (pp. 51-81). Springer-Verlag New York Inc.
    • (2009) , pp. 51-81
    • Ioannou, E.1    Roussis, V.2
  • 42
    • 57349152305 scopus 로고    scopus 로고
    • Antiadult T cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol
    • Ishikawa C., Tafuku S., Kadekaru T., Sawada S., Tomita M., Okudaira T., et al. Antiadult T cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. International Journal of Cancer 2008, 123:2702-2712.
    • (2008) International Journal of Cancer , vol.123 , pp. 2702-2712
    • Ishikawa, C.1    Tafuku, S.2    Kadekaru, T.3    Sawada, S.4    Tomita, M.5    Okudaira, T.6
  • 43
    • 7444222906 scopus 로고    scopus 로고
    • Antioxidant activity of a peptide isolated from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate
    • Je J.Y., Park P.J., Kim S.K. Antioxidant activity of a peptide isolated from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate. Food Research International 2005, 38:45-50.
    • (2005) Food Research International , vol.38 , pp. 45-50
    • Je, J.Y.1    Park, P.J.2    Kim, S.K.3
  • 44
    • 34547684523 scopus 로고    scopus 로고
    • Childhood overweight, obesity, and the metabolic syndrome in developing countries
    • Kelishadi R. Childhood overweight, obesity, and the metabolic syndrome in developing countries. Epidemiologic Reviews 2007, 29:62-76.
    • (2007) Epidemiologic Reviews , vol.29 , pp. 62-76
    • Kelishadi, R.1
  • 45
    • 77953580322 scopus 로고    scopus 로고
    • Protective effect of Amphiroa dilatata on ROS induced oxidative damage and MMP expressions in HT1080 cells
    • Khan S., Kong C., Kim J., Kim S. Protective effect of Amphiroa dilatata on ROS induced oxidative damage and MMP expressions in HT1080 cells. Biotechnology and Bioprocess Engineering 2010, 15:191-198.
    • (2010) Biotechnology and Bioprocess Engineering , vol.15 , pp. 191-198
    • Khan, S.1    Kong, C.2    Kim, J.3    Kim, S.4
  • 46
    • 77649100506 scopus 로고    scopus 로고
    • Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro
    • Khodosevich K., Monyer H. Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro. BMC Neuroscience 2010, 11:18.
    • (2010) BMC Neuroscience , vol.11 , pp. 18
    • Khodosevich, K.1    Monyer, H.2
  • 47
    • 78049236040 scopus 로고    scopus 로고
    • Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages
    • Kim K.N., Heo S.J., Yoon W.J., Kang S.M., Ahn G., Yi T.H., et al. Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages. European Journal of Pharmacology 2010, 649:369-375.
    • (2010) European Journal of Pharmacology , vol.649 , pp. 369-375
    • Kim, K.N.1    Heo, S.J.2    Yoon, W.J.3    Kang, S.M.4    Ahn, G.5    Yi, T.H.6
  • 48
    • 33748447845 scopus 로고    scopus 로고
    • Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease
    • Kim Y., Joh T. Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease. Experimental and Molecular Medicine 2006, 38:333-347.
    • (2006) Experimental and Molecular Medicine , vol.38 , pp. 333-347
    • Kim, Y.1    Joh, T.2
  • 50
    • 79959318881 scopus 로고    scopus 로고
    • A preparative method for isolation of fucoxanthin from Eisenia bicyclis by centrifugal partition chromatography
    • Kim S.M., Shang Y.F., Um B.H. A preparative method for isolation of fucoxanthin from Eisenia bicyclis by centrifugal partition chromatography. Phytochemical Analysis 2011, 222:322-329.
    • (2011) Phytochemical Analysis , vol.222 , pp. 322-329
    • Kim, S.M.1    Shang, Y.F.2    Um, B.H.3
  • 51
    • 77349090649 scopus 로고    scopus 로고
    • Development and biological activities of marine-derived bioactive peptides: A review
    • Kim S., Wijesekara I. Development and biological activities of marine-derived bioactive peptides: A review. Journal of Functional Foods 2010, 2:1-9.
    • (2010) Journal of Functional Foods , vol.2 , pp. 1-9
    • Kim, S.1    Wijesekara, I.2
  • 52
    • 0347987947 scopus 로고    scopus 로고
    • Angiogenesis in multiple sclerosis: Is it good, bad or an epiphenomenon?
    • Kirk S., Frank J.A., Karlik S. Angiogenesis in multiple sclerosis: Is it good, bad or an epiphenomenon?. Journal of the Neurological Sciences 2004, 217:125-130.
    • (2004) Journal of the Neurological Sciences , vol.217 , pp. 125-130
    • Kirk, S.1    Frank, J.A.2    Karlik, S.3
  • 53
    • 69549119861 scopus 로고    scopus 로고
    • Anti-obesity effect of sulfated glucosamine by AMPK signal pathway in 3T3-L1 adipocytes
    • Kong C.S., Kim J.A., Kim S.K. Anti-obesity effect of sulfated glucosamine by AMPK signal pathway in 3T3-L1 adipocytes. Food and Chemical Toxicology 2009, 47:2401-2406.
    • (2009) Food and Chemical Toxicology , vol.47 , pp. 2401-2406
    • Kong, C.S.1    Kim, J.A.2    Kim, S.K.3
  • 54
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman P.G. Obesity as a medical problem. Nature 2000, 404:635-643.
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 55
    • 14644445985 scopus 로고    scopus 로고
    • Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells
    • Kotake Nara E., Asai A., Nagao A. Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells. Cancer Letters 2005, 220:75-84.
    • (2005) Cancer Letters , vol.220 , pp. 75-84
    • Kotake Nara, E.1    Asai, A.2    Nagao, A.3
  • 57
    • 15244357257 scopus 로고    scopus 로고
    • Characterization of apoptosis induced by fucoxanthin in human promyelocytic leukemia cells
    • Kotake Nara E., Terasaki M., Nagao A. Characterization of apoptosis induced by fucoxanthin in human promyelocytic leukemia cells. Bioscience, Biotechnology, and Biochemistry 2005, 69:224-227.
    • (2005) Bioscience, Biotechnology, and Biochemistry , vol.69 , pp. 224-227
    • Kotake Nara, E.1    Terasaki, M.2    Nagao, A.3
  • 61
    • 0031829023 scopus 로고    scopus 로고
    • Antioxidant and pro-oxidant activities of the brown algae, Laminaria digitata, Himanthalia elongata, Fucus vesiculosus, Fucus serratus and Ascophyllum nodosum
    • Le Tutour B., Benslimane F., Gouleau M., Gouygou J., Saadan B., Quemeneur F. Antioxidant and pro-oxidant activities of the brown algae, Laminaria digitata, Himanthalia elongata, Fucus vesiculosus, Fucus serratus and Ascophyllum nodosum. Journal of Applied Phycology 1998, 10:121-129.
    • (1998) Journal of Applied Phycology , vol.10 , pp. 121-129
    • Le Tutour, B.1    Benslimane, F.2    Gouleau, M.3    Gouygou, J.4    Saadan, B.5    Quemeneur, F.6
  • 63
    • 84905581313 scopus 로고    scopus 로고
    • Antiobesity effect of fucoxanthin from edible seaweeds and its multibiological functions. In Functional food and health. ACS Publications.
    • Maeda, H., Hosokawa, M., Sashima, T., & Miyashita, K. (2008). Antiobesity effect of fucoxanthin from edible seaweeds and its multibiological functions. In Functional food and health (pp. 376-388). ACS Publications.
    • (2008) , pp. 376-388
    • Maeda, H.1    Hosokawa, M.2    Sashima, T.3    Miyashita, K.4
  • 64
    • 19444376373 scopus 로고    scopus 로고
    • Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues
    • Maeda H., Hosokawa M., Sashima T., Funayama K., Miyashita K. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochemical and Biophysical Research Communications 2005, 332:392-397.
    • (2005) Biochemical and Biophysical Research Communications , vol.332 , pp. 392-397
    • Maeda, H.1    Hosokawa, M.2    Sashima, T.3    Funayama, K.4    Miyashita, K.5
  • 66
    • 34948878515 scopus 로고    scopus 로고
    • Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice
    • Maeda H., Hosokawa M., Sashima T., Miyashita K. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Journal of Agricultural and Food Chemistry 2007, 55:7701-7706.
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , pp. 7701-7706
    • Maeda, H.1    Hosokawa, M.2    Sashima, T.3    Miyashita, K.4
  • 67
    • 73649136846 scopus 로고    scopus 로고
    • Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model
    • Maeda H., Hosokawa M., Sashima T., Murakami-Funayama K., Miyashita K. Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model. Molecular Medicine Reports 2009, 2:897-902.
    • (2009) Molecular Medicine Reports , vol.2 , pp. 897-902
    • Maeda, H.1    Hosokawa, M.2    Sashima, T.3    Murakami-Funayama, K.4    Miyashita, K.5
  • 68
    • 0013279235 scopus 로고    scopus 로고
    • Aquatic animal carotenoids
    • Matsuno T. Aquatic animal carotenoids. Fisheries Science 2001, 67:771-783.
    • (2001) Fisheries Science , vol.67 , pp. 771-783
    • Matsuno, T.1
  • 70
    • 39549091694 scopus 로고    scopus 로고
    • Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy
    • Narang S., Gibson D., Wasan A.D., Ross E.L., Michna E., Nedeljkovic S.S., et al. Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy. The Journal of Pain 2008, 9:254-264.
    • (2008) The Journal of Pain , vol.9 , pp. 254-264
    • Narang, S.1    Gibson, D.2    Wasan, A.D.3    Ross, E.L.4    Michna, E.5    Nedeljkovic, S.S.6
  • 71
    • 79952314733 scopus 로고    scopus 로고
    • Marine food-derived functional ingredients as potential antioxidants in the food industry: An overview
    • Ngo D.H., Wijesekara I., Vo T.S., Van Ta Q., Kim S.K. Marine food-derived functional ingredients as potential antioxidants in the food industry: An overview. Food Research International 2010, 44:523-529.
    • (2010) Food Research International , vol.44 , pp. 523-529
    • Ngo, D.H.1    Wijesekara, I.2    Vo, T.S.3    Van Ta, Q.4    Kim, S.K.5
  • 72
    • 0034621353 scopus 로고    scopus 로고
    • Voltammetric determination of butylated hydroxyanisole, butylated hydroxytoluene, propyl gallate and tert-butylhydroquinone by use of chemometric approaches
    • Ni Y., Wang L., Kokot S. Voltammetric determination of butylated hydroxyanisole, butylated hydroxytoluene, propyl gallate and tert-butylhydroquinone by use of chemometric approaches. Analytica Chimica Acta 2000, 412:185-193.
    • (2000) Analytica Chimica Acta , vol.412 , pp. 185-193
    • Ni, Y.1    Wang, L.2    Kokot, S.3
  • 73
    • 0031394857 scopus 로고    scopus 로고
    • Proton-donative antioxidant activity of fucoxanthin with 1,1-diphenyl-2-picrylhydrazyl (DPPH)
    • Nomura T., Kikuchi M., Kubodera A., Kawakami Y. Proton-donative antioxidant activity of fucoxanthin with 1,1-diphenyl-2-picrylhydrazyl (DPPH). IUBMB Life 1997, 42:361-370.
    • (1997) IUBMB Life , vol.42 , pp. 361-370
    • Nomura, T.1    Kikuchi, M.2    Kubodera, A.3    Kawakami, Y.4
  • 75
    • 0030802185 scopus 로고    scopus 로고
    • Pheophytin a is a potent suppressor against genotoxin induced umuC gene expression in Salmonella typhimurium (TA 1535/pSK 1002)
    • Okai Y., Higashi Okai K. Pheophytin a is a potent suppressor against genotoxin induced umuC gene expression in Salmonella typhimurium (TA 1535/pSK 1002). Journal of the Science of Food and Agriculture 1997, 74:531-535.
    • (1997) Journal of the Science of Food and Agriculture , vol.74 , pp. 531-535
    • Okai, Y.1    Higashi Okai, K.2
  • 76
    • 0031454220 scopus 로고    scopus 로고
    • Potent anti-inflammatory activity of pheophytin a derived from edible green alga, Enteromorpha prolifera (Sujiao-nori)
    • Okai Y., Hiqashi Okai K. Potent anti-inflammatory activity of pheophytin a derived from edible green alga, Enteromorpha prolifera (Sujiao-nori). International Journal of Immunopharmacology 1997, 19:355-358.
    • (1997) International Journal of Immunopharmacology , vol.19 , pp. 355-358
    • Okai, Y.1    Hiqashi Okai, K.2
  • 77
    • 0030040548 scopus 로고    scopus 로고
    • Identification of antimutagenic substances in an extract of edible red alga, Porphyra tenera (Asadusa-nori)
    • Okai Y., Hiqashi Okai K., Yano Y., Otani S. Identification of antimutagenic substances in an extract of edible red alga, Porphyra tenera (Asadusa-nori). Cancer Letters 1996, 100:235-240.
    • (1996) Cancer Letters , vol.100 , pp. 235-240
    • Okai, Y.1    Hiqashi Okai, K.2    Yano, Y.3    Otani, S.4
  • 78
    • 0025602410 scopus 로고
    • Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells
    • Okuzumi J., Nishino H., Murakoshi M., Iwashima A., Tanaka Y., Yamane T., et al. Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells. Cancer Letters 1990, 55:75-81.
    • (1990) Cancer Letters , vol.55 , pp. 75-81
    • Okuzumi, J.1    Nishino, H.2    Murakoshi, M.3    Iwashima, A.4    Tanaka, Y.5    Yamane, T.6
  • 79
    • 77955285406 scopus 로고    scopus 로고
    • Neuroprotective properties of chitosan and its derivatives
    • Pangestuti R., Kim S.K. Neuroprotective properties of chitosan and its derivatives. Marine Drugs 2010, 8:2117-2128.
    • (2010) Marine Drugs , vol.8 , pp. 2117-2128
    • Pangestuti, R.1    Kim, S.K.2
  • 80
    • 79957648966 scopus 로고    scopus 로고
    • Neuroprotective effects of marine algae
    • Pangestuti R., Kim S.K. Neuroprotective effects of marine algae. Marine Drugs 2011, 9:803-818.
    • (2011) Marine Drugs , vol.9 , pp. 803-818
    • Pangestuti, R.1    Kim, S.K.2
  • 81
    • 0035358387 scopus 로고    scopus 로고
    • Purification and characterization of antioxidative peptides from protein hydrolysate of lecithin-free egg yolk
    • Park P., Jung W., Nam K., Shahidi F., Kim S. Purification and characterization of antioxidative peptides from protein hydrolysate of lecithin-free egg yolk. Journal of the American Oil Chemists' Society 2001, 78:651-656.
    • (2001) Journal of the American Oil Chemists' Society , vol.78 , pp. 651-656
    • Park, P.1    Jung, W.2    Nam, K.3    Shahidi, F.4    Kim, S.5
  • 82
    • 0035755659 scopus 로고    scopus 로고
    • Antioxidative activity of whey protein hydrolysates in a liposomal system
    • Pena-Ramos E., Xiong Y. Antioxidative activity of whey protein hydrolysates in a liposomal system. Journal of Dairy Science 2001, 84:2577-2583.
    • (2001) Journal of Dairy Science , vol.84 , pp. 2577-2583
    • Pena-Ramos, E.1    Xiong, Y.2
  • 83
    • 0036132096 scopus 로고    scopus 로고
    • Estimates of the world-wide prevalence of cancer for 25 sites in the adult population
    • Pisani P., Bray F., Parkin D. Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. International Journal of Cancer 2002, 97:72-81.
    • (2002) International Journal of Cancer , vol.97 , pp. 72-81
    • Pisani, P.1    Bray, F.2    Parkin, D.3
  • 84
    • 0042484813 scopus 로고    scopus 로고
    • The obesity epidemic: Pathophysiology and consequences of obesity
    • Pi-Sunyer F. The obesity epidemic: Pathophysiology and consequences of obesity. Obesity 2002, 10:97S-104S.
    • (2002) Obesity , vol.10
    • Pi-Sunyer, F.1
  • 85
    • 57249097140 scopus 로고    scopus 로고
    • Fucoxanthin restrains oxidative stress induced by retinol deficiency through modulation of Na+ Ka+-ATPase and antioxidant enzyme activities in rats
    • Ravi Kumar S., Narayan B., Vallikannan B. Fucoxanthin restrains oxidative stress induced by retinol deficiency through modulation of Na+ Ka+-ATPase and antioxidant enzyme activities in rats. European Journal of Nutrition 2008, 47:432-441.
    • (2008) European Journal of Nutrition , vol.47 , pp. 432-441
    • Ravi Kumar, S.1    Narayan, B.2    Vallikannan, B.3
  • 86
    • 59849110877 scopus 로고    scopus 로고
    • Extraction of fucoxanthin and polyphenol from Undaria pinnatifida using supercritical carbon dioxide with co-solvent
    • Roh M.K., Uddin M.S., Chun B.S. Extraction of fucoxanthin and polyphenol from Undaria pinnatifida using supercritical carbon dioxide with co-solvent. Biotechnology and Bioprocess Engineering 2008, 13:724-729.
    • (2008) Biotechnology and Bioprocess Engineering , vol.13 , pp. 724-729
    • Roh, M.K.1    Uddin, M.S.2    Chun, B.S.3
  • 88
    • 0032953576 scopus 로고    scopus 로고
    • Hepatotoxicity induced by the anti-oxidant food additive, butylated hydroxytoluene (BHT), in rats: An electron microscopical study
    • Safer A., Al-Nughamish A. Hepatotoxicity induced by the anti-oxidant food additive, butylated hydroxytoluene (BHT), in rats: An electron microscopical study. Histology and Histopathology 1999, 14:391-406.
    • (1999) Histology and Histopathology , vol.14 , pp. 391-406
    • Safer, A.1    Al-Nughamish, A.2
  • 89
    • 74049106642 scopus 로고    scopus 로고
    • Comparative effects of β-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats
    • Sangeetha R., Bhaskar N., Baskaran V. Comparative effects of β-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats. Molecular and Cellular Biochemistry 2009, 331:59-67.
    • (2009) Molecular and Cellular Biochemistry , vol.331 , pp. 59-67
    • Sangeetha, R.1    Bhaskar, N.2    Baskaran, V.3
  • 90
    • 73449119904 scopus 로고    scopus 로고
    • Bioavailability and metabolism of fucoxanthin in rats: structural characterization of metabolites by LC-MS (APCI)
    • Sangeetha R., Bhaskar N., Divakar S., Baskaran V. Bioavailability and metabolism of fucoxanthin in rats: structural characterization of metabolites by LC-MS (APCI). Molecular and Cellular Biochemistry 2010, 333:299-310.
    • (2010) Molecular and Cellular Biochemistry , vol.333 , pp. 299-310
    • Sangeetha, R.1    Bhaskar, N.2    Divakar, S.3    Baskaran, V.4
  • 91
    • 51149119492 scopus 로고    scopus 로고
    • Effects of fucoxanthin addition to ground chicken breast meat on lipid and colour stability during chilled storage, before and after cooking
    • Sasaki K., Ishihara K., Oyamada C., Sato A., Fukushi A., Arakane T., et al. Effects of fucoxanthin addition to ground chicken breast meat on lipid and colour stability during chilled storage, before and after cooking. Asian-Australasian Journal of Animal Sciences 2008, 21:1067-1072.
    • (2008) Asian-Australasian Journal of Animal Sciences , vol.21 , pp. 1067-1072
    • Sasaki, K.1    Ishihara, K.2    Oyamada, C.3    Sato, A.4    Fukushi, A.5    Arakane, T.6
  • 92
    • 78249238199 scopus 로고    scopus 로고
    • Oral administration of fucoxanthin increases plasma fucoxanthinol concentration and antioxidative ability and improves meat color in broiler chicks
    • Sasaki K., Ishihara K., Yamazaki M., Nakashima K., Abe H., Oyamada C., et al. Oral administration of fucoxanthin increases plasma fucoxanthinol concentration and antioxidative ability and improves meat color in broiler chicks. The Journal of Poultry Science 2010, 47:316-320.
    • (2010) The Journal of Poultry Science , vol.47 , pp. 316-320
    • Sasaki, K.1    Ishihara, K.2    Yamazaki, M.3    Nakashima, K.4    Abe, H.5    Oyamada, C.6
  • 93
    • 41049106722 scopus 로고    scopus 로고
    • Phycobiliproteins as a commodity: Trends in applied research, patents and commercialization
    • Sekar S., Chandramohan M. Phycobiliproteins as a commodity: Trends in applied research, patents and commercialization. Journal of Applied Phycology 2008, 20:113-136.
    • (2008) Journal of Applied Phycology , vol.20 , pp. 113-136
    • Sekar, S.1    Chandramohan, M.2
  • 94
    • 84880514756 scopus 로고    scopus 로고
    • Bioactives from marine resources. In ACS symposium series. ACS Publications.
    • Shahidi, F. (2008). Bioactives from marine resources. In ACS symposium series (pp. 24-34). ACS Publications.
    • (2008) , pp. 24-34
    • Shahidi, F.1
  • 95
    • 84885534955 scopus 로고    scopus 로고
    • Marine oils and other marine nutraceuticals. In Handbook of seafood quality, safety and health applications. Wiley Online Library.
    • Shahidi, F., & Alasalvar, C. (2011). Marine oils and other marine nutraceuticals. In Handbook of seafood quality, safety and health applications (pp. 444-454). Wiley Online Library.
    • (2011) , pp. 444-454
    • Shahidi, F.1    Alasalvar, C.2
  • 96
    • 0035746634 scopus 로고    scopus 로고
    • Enzymes from fish and aquatic invertebrates and their application in the food industry
    • Shahidi F., Janak Kamil Y. Enzymes from fish and aquatic invertebrates and their application in the food industry. Trends in Food Science and Technology 2001, 12:435-464.
    • (2001) Trends in Food Science and Technology , vol.12 , pp. 435-464
    • Shahidi, F.1    Janak Kamil, Y.2
  • 97
    • 78951479528 scopus 로고    scopus 로고
    • Pressurized liquid method for fucoxanthin extraction from Eisenia bicyclis (Kjellman) Setchell
    • Shang Y.F., Kim S.M., Lee W.J., Um B.H. Pressurized liquid method for fucoxanthin extraction from Eisenia bicyclis (Kjellman) Setchell. Journal of Bioscience and Bioengineering 2010, 111:237-241.
    • (2010) Journal of Bioscience and Bioengineering , vol.111 , pp. 237-241
    • Shang, Y.F.1    Kim, S.M.2    Lee, W.J.3    Um, B.H.4
  • 98
    • 77955262356 scopus 로고    scopus 로고
    • Anti-pigmentary activity of fucoxanthin and its influence on skin mRNA expression of melanogenic molecules
    • Shimoda H., Tanaka J., Shan S., Maoka T. Anti-pigmentary activity of fucoxanthin and its influence on skin mRNA expression of melanogenic molecules. Journal of Pharmacy and Pharmacology 2010, 62:1137-1145.
    • (2010) Journal of Pharmacy and Pharmacology , vol.62 , pp. 1137-1145
    • Shimoda, H.1    Tanaka, J.2    Shan, S.3    Maoka, T.4
  • 100
    • 23644447192 scopus 로고    scopus 로고
    • Rheological characterization of coloured oil-in-water food emulsions with lutein and phycocyanin added to the oil and aqueous phases
    • Sousa I., Batista A.P., Raymundo A., Empis J. Rheological characterization of coloured oil-in-water food emulsions with lutein and phycocyanin added to the oil and aqueous phases. Food Hydrocolloids 2006, 20:44-52.
    • (2006) Food Hydrocolloids , vol.20 , pp. 44-52
    • Sousa, I.1    Batista, A.P.2    Raymundo, A.3    Empis, J.4
  • 102
    • 0036256640 scopus 로고    scopus 로고
    • Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice
    • Sugawara T., Baskaran V., Tsuzuki W., Nagao A. Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice. The Journal of Nutrition 2002, 132:946-951.
    • (2002) The Journal of Nutrition , vol.132 , pp. 946-951
    • Sugawara, T.1    Baskaran, V.2    Tsuzuki, W.3    Nagao, A.4
  • 105
    • 0042916313 scopus 로고    scopus 로고
    • What future for the oceans?
    • Swing J. What future for the oceans?. Foreign Affairs 2003, 82:139-152.
    • (2003) Foreign Affairs , vol.82 , pp. 139-152
    • Swing, J.1
  • 106
    • 69849096803 scopus 로고    scopus 로고
    • Evaluation of recoverable functional lipid components of several brown seaweeds (Phaeophyta) from Japan with special reference to fucoxanthin and fucosterol contents
    • Terasaki M., Hirose A., Narayan B., Baba Y., Kawagoe C., Yasui H., et al. Evaluation of recoverable functional lipid components of several brown seaweeds (Phaeophyta) from Japan with special reference to fucoxanthin and fucosterol contents. Journal of Phycology 2009, 45:974-980.
    • (2009) Journal of Phycology , vol.45 , pp. 974-980
    • Terasaki, M.1    Hirose, A.2    Narayan, B.3    Baba, Y.4    Kawagoe, C.5    Yasui, H.6
  • 107
    • 0037373087 scopus 로고    scopus 로고
    • Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: A review of the epidemiologic evidence
    • Terry P., Rohan T., Wolk A. Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: A review of the epidemiologic evidence. American Journal of Clinical Nutrition 2003, 77:532-543.
    • (2003) American Journal of Clinical Nutrition , vol.77 , pp. 532-543
    • Terry, P.1    Rohan, T.2    Wolk, A.3
  • 108
    • 27844545767 scopus 로고    scopus 로고
    • Signalling role of adipose tissue: Adipokines and inflammation in obesity
    • Trayhurn P., Wood I.S. Signalling role of adipose tissue: Adipokines and inflammation in obesity. Biochemical Society Transactions 2005, 33:1078-1081.
    • (2005) Biochemical Society Transactions , vol.33 , pp. 1078-1081
    • Trayhurn, P.1    Wood, I.S.2
  • 109
    • 67651097613 scopus 로고    scopus 로고
    • Enhancement of hepatic docosahexaenoic acid and arachidonic acid contents in C57BL/6J mice by dietary fucoxanthin
    • Tsukui T., Baba N., Hosokawa M., Sashima T., Miyashita K. Enhancement of hepatic docosahexaenoic acid and arachidonic acid contents in C57BL/6J mice by dietary fucoxanthin. Fisheries Science 2009, 75:261-263.
    • (2009) Fisheries Science , vol.75 , pp. 261-263
    • Tsukui, T.1    Baba, N.2    Hosokawa, M.3    Sashima, T.4    Miyashita, K.5
  • 112
    • 7344245077 scopus 로고    scopus 로고
    • Effet de synergie de la chlorophylle a sur les proprietes antioxydantes de la vitamine E
    • Tutour B.L., Brunel C., Quemeneur F. Effet de synergie de la chlorophylle a sur les proprietes antioxydantes de la vitamine E. New Journal of Chemistry 1996, 20:707.
    • (1996) New Journal of Chemistry , vol.20 , pp. 707
    • Tutour, B.L.1    Brunel, C.2    Quemeneur, F.3
  • 113
    • 37549014582 scopus 로고    scopus 로고
    • Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling
    • Wang T., Wang Y., Kontani Y., Kobayashi Y., Sato Y., Mori N., et al. Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling. Endocrinology 2008, 149:358-366.
    • (2008) Endocrinology , vol.149 , pp. 358-366
    • Wang, T.1    Wang, Y.2    Kontani, Y.3    Kobayashi, Y.4    Sato, Y.5    Mori, N.6
  • 114
    • 71149121153 scopus 로고    scopus 로고
    • Anti-obese property of fucoxanthin is partly mediated by altering lipid-regulating enzymes and uncoupling proteins of visceral adipose tissue in mice
    • Woo M.N., Jeon S.M., Shin Y.C., Lee M.K., Kang M.A., Choi M.S. Anti-obese property of fucoxanthin is partly mediated by altering lipid-regulating enzymes and uncoupling proteins of visceral adipose tissue in mice. Molecular Nutrition and Food Research 2009, 53:1603-1611.
    • (2009) Molecular Nutrition and Food Research , vol.53 , pp. 1603-1611
    • Woo, M.N.1    Jeon, S.M.2    Shin, Y.C.3    Lee, M.K.4    Kang, M.A.5    Choi, M.S.6
  • 115
    • 77956248775 scopus 로고    scopus 로고
    • Antioxidant activity of the phycoerythrobilin compound formed from a dried Korean purple laver (Porphyra sp.) during in vitro digestion
    • Yabuta Y., Fujimura H., Kwak C.S., Enomoto T., Watanabe F. Antioxidant activity of the phycoerythrobilin compound formed from a dried Korean purple laver (Porphyra sp.) during in vitro digestion. Food Science and Technology Research 2010, 16:347-352.
    • (2010) Food Science and Technology Research , vol.16 , pp. 347-352
    • Yabuta, Y.1    Fujimura, H.2    Kwak, C.S.3    Enomoto, T.4    Watanabe, F.5
  • 116
  • 117
    • 33744939692 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activities of extracts from a variety of edible seaweeds
    • Yuan Y., Walsh N. Antioxidant and antiproliferative activities of extracts from a variety of edible seaweeds. Food and Chemical Toxicology 2006, 44:1144-1150.
    • (2006) Food and Chemical Toxicology , vol.44 , pp. 1144-1150
    • Yuan, Y.1    Walsh, N.2


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