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Volumn 65, Issue 9, 2011, Pages 2421-2434

Recombination and hitchhiking of deleterious alleles

Author keywords

Deleterious mutations; Diffusion equations; Genetic hitchhiking; Hill Robertson effects; Selective sweep

Indexed keywords

ALLELE; DIFFUSION; EVOLUTIONARY BIOLOGY; GENETIC ANALYSIS; GENOME; HUMAN EVOLUTION; MUTATION; RECOMBINATION;

EID: 80052264437     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/j.1558-5646.2011.01311.x     Document Type: Article
Times cited : (66)

References (63)
  • 2
    • 27144491328 scopus 로고    scopus 로고
    • Adaptive evolution of non-coding DNA in Drosophila
    • Andolfatto, P. 2005. Adaptive evolution of non-coding DNA in Drosophila. Nature 437:1149-1152.
    • (2005) Nature , vol.437 , pp. 1149-1152
    • Andolfatto, P.1
  • 3
    • 38849194141 scopus 로고    scopus 로고
    • Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome
    • Andolfatto, P. 2007. Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome. Genome Res. 17:1755-1762.
    • (2007) Genome Res. , vol.17 , pp. 1755-1762
    • Andolfatto, P.1
  • 4
    • 3543125439 scopus 로고    scopus 로고
    • Adaptive evolution of asexual populations under Muller's ratchet
    • Bachtrog, D., and I. Gordo. 2004. Adaptive evolution of asexual populations under Muller's ratchet. Evolution 58:1403-1413.
    • (2004) Evolution , vol.58 , pp. 1403-1413
    • Bachtrog, D.1    Gordo, I.2
  • 5
    • 33645112661 scopus 로고    scopus 로고
    • Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations
    • Barrett, R. D. H., R. Craig MacLean, and G. Bell. 2006. Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations. Biol. Lett. 2:236-238.
    • (2006) Biol. Lett. , vol.2 , pp. 236-238
    • Barrett, R.D.H.1    MacLean, R.C.2    Bell, G.3
  • 6
    • 0028625609 scopus 로고
    • The reduction in fixation probability caused by substitutions at linked loci
    • Barton, N. H. 1994. The reduction in fixation probability caused by substitutions at linked loci. Genet. Res. 64:199-208.
    • (1994) Genet. Res. , vol.64 , pp. 199-208
    • Barton, N.H.1
  • 7
    • 0029040245 scopus 로고
    • Linkage and the limits to natural selection
    • Barton, N. H. 1995. Linkage and the limits to natural selection. Genetics 140:821-841.
    • (1995) Genetics , vol.140 , pp. 821-841
    • Barton, N.H.1
  • 8
    • 18844399355 scopus 로고    scopus 로고
    • Evolution of recombination due to random drift
    • Barton, N. H., and S. P. Otto. 2005. Evolution of recombination due to random drift. Genetics 169:2353-2370.
    • (2005) Genetics , vol.169 , pp. 2353-2370
    • Barton, N.H.1    Otto, S.P.2
  • 9
    • 0037108764 scopus 로고    scopus 로고
    • Linkage limits the power of natural selection in Drosophila
    • Betancourt, A. J., and D. C. Presgraves. 2002. Linkage limits the power of natural selection in Drosophila. Proc. Natl. Acad. Sci. USA 99:13616-13620.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13616-13620
    • Betancourt, A.J.1    Presgraves, D.C.2
  • 10
    • 3042544623 scopus 로고    scopus 로고
    • The genomic rate of adaptive amino acid substitution in Drosophila
    • Bierne, N., and A. Eyre-Walker. 2004. The genomic rate of adaptive amino acid substitution in Drosophila. Mol. Biol. Evol. 21:1350-1360.
    • (2004) Mol. Biol. Evol. , vol.21 , pp. 1350-1360
    • Bierne, N.1    Eyre-Walker, A.2
  • 12
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic maps: individual and sex-specific variation in recombination
    • Broman, K. W., J. C. Murray, V. C. Sheffield, R. L. White, and J. L. Weber. 1998. Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am. J. Hum. Genet. 63:861-869.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 861-869
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3    White, R.L.4    Weber, J.L.5
  • 13
    • 0034035485 scopus 로고    scopus 로고
    • Big-benefit mutations in a bacteriophage inhibited with heat
    • Bull, J. J., M. R. Badgett, and H. A. Wichman. 2000. Big-benefit mutations in a bacteriophage inhibited with heat. Mol. Biol. Evol. 17:942-950.
    • (2000) Mol. Biol. Evol. , vol.17 , pp. 942-950
    • Bull, J.J.1    Badgett, M.R.2    Wichman, H.A.3
  • 14
    • 0027305597 scopus 로고
    • The effect of deleterious mutations on neutral molecular variation
    • Charlesworth, B., M. T. Morgan, and D. Charlesworth. 1993. The effect of deleterious mutations on neutral molecular variation. Genetics 134:1289-1303.
    • (1993) Genetics , vol.134 , pp. 1289-1303
    • Charlesworth, B.1    Morgan, M.T.2    Charlesworth, D.3
  • 16
    • 0002160422 scopus 로고
    • Genetic loads and the cost of natural selection
    • K. I. Kojima, ed., Biomathematics, Springer-Verlag, Berlin
    • Crow, J. F. 1970. Genetic loads and the cost of natural selection. Pp. 128-177, in K. I. Kojima, ed. Mathematical topics in population genetics, Biomathematics, vol. 1. Springer-Verlag, Berlin.
    • (1970) Mathematical topics in population genetics , vol.1 , pp. 128-177
    • Crow, J.F.1
  • 17
    • 33847314378 scopus 로고    scopus 로고
    • Beneficial mutation-selection balance and the effect of linkage on positive selection
    • Desai, M. M., and D. S. Fisher. 2007. Beneficial mutation-selection balance and the effect of linkage on positive selection. Genetics 176:1759-1798.
    • (2007) Genetics , vol.176 , pp. 1759-1798
    • Desai, M.M.1    Fisher, D.S.2
  • 18
    • 0038441327 scopus 로고    scopus 로고
    • Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation
    • Elena, S. F., and R. E. Lenski. 2003. Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation. Nat. Rev. Genet. 4:457-469.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 457-469
    • Elena, S.F.1    Lenski, R.E.2
  • 19
    • 72649102150 scopus 로고    scopus 로고
    • Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes
    • Eöry, L., D. L. Halligan, and P. D. Keightley. 2010. Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes. Mol. Biol. Evol. 27:177-192.
    • (2010) Mol. Biol. Evol. , vol.27 , pp. 177-192
    • Eöry, L.1    Halligan, D.L.2    Keightley, P.D.3
  • 20
    • 72449161816 scopus 로고    scopus 로고
    • Mathematical population genetics: 1. Theoretical introduction
    • 2nd ed. Springer, New York
    • Ewens, W. J. 2004. Mathematical population genetics: 1. Theoretical introduction, Interdisciplinary applied mathematics, Vol. 27. 2nd ed. Springer, New York.
    • (2004) Interdisciplinary applied mathematics , vol.27
    • Ewens, W.J.1
  • 21
    • 33748473348 scopus 로고    scopus 로고
    • The genomic rate of adaptive evolution
    • Eyre-Walker, A. 2006. The genomic rate of adaptive evolution. Trends Ecol. Evol. 21:569-575.
    • (2006) Trends Ecol. Evol. , vol.21 , pp. 569-575
    • Eyre-Walker, A.1
  • 22
    • 68949202924 scopus 로고    scopus 로고
    • Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change
    • Eyre-Walker, A., and P. D. Keightley. 2009. Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. Mol. Biol. Evol. 26:2097-2108.
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 2097-2108
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 23
    • 33745347447 scopus 로고    scopus 로고
    • The distribution of fitness effects of new deleterious amino acid mutations in humans
    • Eyre-Walker, A., M. Woolfit, and T. Phelps. 2006. The distribution of fitness effects of new deleterious amino acid mutations in humans. Genetics 173:891-900.
    • (2006) Genetics , vol.173 , pp. 891-900
    • Eyre-Walker, A.1    Woolfit, M.2    Phelps, T.3
  • 26
    • 14844356767 scopus 로고    scopus 로고
    • Evolutionary traction: the cost of adaptation and the evolution of sex
    • Hadany, L., and M. W. Feldman. 2005. Evolutionary traction: the cost of adaptation and the evolution of sex. J. Evol. Biol. 18:309-314.
    • (2005) J. Evol. Biol. , vol.18 , pp. 309-314
    • Hadany, L.1    Feldman, M.W.2
  • 27
    • 0002341847 scopus 로고
    • A mathematical theory of natural and artificial selection, part I
    • Haldane, J. 1924. A mathematical theory of natural and artificial selection, part I. Trans. Cambridge Philos. Soc. 23:19-41.
    • (1924) Trans. Cambridge Philos. Soc. , vol.23 , pp. 19-41
    • Haldane, J.1
  • 28
    • 84955349191 scopus 로고
    • A mathematical theory of natural and artificial selection, part V: Selection and mutation
    • Haldane, J. B. S. 1927. A mathematical theory of natural and artificial selection, part V: Selection and mutation. Math. Proc. Cambridge Philos. Soc. 23:838-844.
    • (1927) Math. Proc. Cambridge Philos. Soc. , vol.23 , pp. 838-844
    • Haldane, J.B.S.1
  • 29
    • 78751615060 scopus 로고    scopus 로고
    • A high frequency of beneficial mutations across multiple fitness components in Saccharomyces cerevisiae
    • Hall, D. W., and S. B. Joseph. 2010. A high frequency of beneficial mutations across multiple fitness components in Saccharomyces cerevisiae. Genetics 185:1397-1409.
    • (2010) Genetics , vol.185 , pp. 1397-1409
    • Hall, D.W.1    Joseph, S.B.2
  • 31
    • 77955909886 scopus 로고    scopus 로고
    • The role of advantageous mutations in enhancing the evolution of a recombination modifier
    • Hartfield, M., S. P. Otto, and P. D. Keightley. 2010. The role of advantageous mutations in enhancing the evolution of a recombination modifier. Genetics 184:1153-1164.
    • (2010) Genetics , vol.184 , pp. 1153-1164
    • Hartfield, M.1    Otto, S.P.2    Keightley, P.D.3
  • 32
    • 34249014299 scopus 로고    scopus 로고
    • The role of pleiotropy in the maintenance of sex in yeast
    • Hill, J. A., and S. P. Otto. 2007. The role of pleiotropy in the maintenance of sex in yeast. Genetics 175:1419-1427.
    • (2007) Genetics , vol.175 , pp. 1419-1427
    • Hill, J.A.1    Otto, S.P.2
  • 33
    • 0013979181 scopus 로고
    • The effect of linkage on limits to artificial selection
    • Hill, W. G., and A. Robertson. 1966. The effect of linkage on limits to artificial selection. Genet. Res. 8:269-294.
    • (1966) Genet. Res. , vol.8 , pp. 269-294
    • Hill, W.G.1    Robertson, A.2
  • 34
    • 0023339852 scopus 로고
    • A test of neutral molecular evolution based on nucleotide data
    • Hudson, R. R., M. Kreitman, and M. Aguade. 1987. A test of neutral molecular evolution based on nucleotide data. Genetics 116:153-159.
    • (1987) Genetics , vol.116 , pp. 153-159
    • Hudson, R.R.1    Kreitman, M.2    Aguade, M.3
  • 35
    • 52949128377 scopus 로고    scopus 로고
    • An approximate Bayesian estimator suggests strong, recurrent selective sweeps in Drosophila
    • Jensen, J. D., K. R. Thornton, and P. Andolfatto. 2008. An approximate Bayesian estimator suggests strong, recurrent selective sweeps in Drosophila. PLoS Genet. 4:e1000198.
    • (2008) PLoS Genet. , vol.4
    • Jensen, J.D.1    Thornton, K.R.2    Andolfatto, P.3
  • 36
    • 0036741701 scopus 로고    scopus 로고
    • The effect of deleterious alleles on adaptation in asexual populations
    • Johnson, T., and N. H. Barton. 2002. The effect of deleterious alleles on adaptation in asexual populations. Genetics 162:395-411.
    • (2002) Genetics , vol.162 , pp. 395-411
    • Johnson, T.1    Barton, N.H.2
  • 37
    • 0032006951 scopus 로고    scopus 로고
    • Using mitochondrial and nuclear DNA markers to reconstruct human evolution
    • Jorde, L. B., M. Bamshad, and A. R. Rogers. 1998. Using mitochondrial and nuclear DNA markers to reconstruct human evolution. BioEssays 20:126-136.
    • (1998) BioEssays , vol.20 , pp. 126-136
    • Jorde, L.B.1    Bamshad, M.2    Rogers, A.R.3
  • 38
    • 11244275516 scopus 로고    scopus 로고
    • Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected
    • Joseph, S. B., and D. W. Hall. 2004. Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected. Genetics 168:1817-1825.
    • (2004) Genetics , vol.168 , pp. 1817-1825
    • Joseph, S.B.1    Hall, D.W.2
  • 41
    • 0037360124 scopus 로고    scopus 로고
    • Towards a realistic model of mutations affecting fitness
    • Keightley, P. D., and M. Lynch. 2003. Towards a realistic model of mutations affecting fitness. Evolution 57:683-685.
    • (2003) Evolution , vol.57 , pp. 683-685
    • Keightley, P.D.1    Lynch, M.2
  • 42
    • 33748428600 scopus 로고    scopus 로고
    • Interference among deleterious mutations favours sex and recombination in finite populations
    • Keightley, P. D., and S. P. Otto. 2006. Interference among deleterious mutations favours sex and recombination in finite populations. Nature 443:89-92.
    • (2006) Nature , vol.443 , pp. 89-92
    • Keightley, P.D.1    Otto, S.P.2
  • 43
    • 67650064592 scopus 로고    scopus 로고
    • Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines
    • Keightley, P. D., U. Trivedi, M. Thomson, F. Oliver, S. Kumar, and M. L. Blaxter. 2009. Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines. Genome Res. 19:1195-1201.
    • (2009) Genome Res. , vol.19 , pp. 1195-1201
    • Keightley, P.D.1    Trivedi, U.2    Thomson, M.3    Oliver, F.4    Kumar, S.5    Blaxter, M.L.6
  • 44
    • 0039958737 scopus 로고
    • Stochastic processes in population genetics
    • K. -I. Kojima, ed., Biomathematics, Springer-Verlag; Heidelberg; New York, Berlin
    • Kimura, M. 1970. Stochastic processes in population genetics. Pp. 178-209, in K. -I. Kojima, ed. Mathematical Topics in Population Genetics, Biomathematics, vol. 1. Springer-Verlag; Heidelberg; New York, Berlin.
    • (1970) Mathematical Topics in Population Genetics , vol.1 , pp. 178-209
    • Kimura, M.1
  • 46
    • 0014818886 scopus 로고
    • Probability of fixation of a mutant gene in a finite population when selective advantage decreases with time
    • Kimura, M., and T. Ohta. 1970. Probability of fixation of a mutant gene in a finite population when selective advantage decreases with time. Genetics 65:525-534.
    • (1970) Genetics , vol.65 , pp. 525-534
    • Kimura, M.1    Ohta, T.2
  • 47
    • 0016220238 scopus 로고
    • The hitch-hiking effect of a favourable gene
    • Smith, J. Maynard, and J. Haigh. 1974. The hitch-hiking effect of a favourable gene. Genet. Res. 23:23-35.
    • (1974) Genet. Res. , vol.23 , pp. 23-35
    • Smith, J.M.1    Haigh, J.2
  • 48
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean, G. A. T., S. R. Myers, S. Hunt, P. Deloukas, D. R. Bentley, and P. Donnelly. 2004. The fine-scale structure of recombination rate variation in the human genome. Science 304:581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.T.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5    Donnelly, P.6
  • 49
    • 29444452921 scopus 로고    scopus 로고
    • Molecular signals of natural selection
    • Nielsen, R. 2005. Molecular signals of natural selection. Annu. Rev. Genet. 39:197-218.
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 197-218
    • Nielsen, R.1
  • 50
    • 73449137909 scopus 로고    scopus 로고
    • Quantifying adaptive evolution in the Drosophila immune system
    • Obbard, D. J., J. J. Welch, K.-W. Kim, and F. M. Jiggins. 2009. Quantifying adaptive evolution in the Drosophila immune system. PLoS Genet. 5:e1000698.
    • (2009) PLoS Genet. , vol.5
    • Obbard, D.J.1    Welch, J.J.2    Kim, K.-W.3    Jiggins, F.M.4
  • 51
    • 68549133539 scopus 로고    scopus 로고
    • The evolutionary enigma of sex
    • Otto, S. P. 2009. The evolutionary enigma of sex. Am. Nat. 174:S1-S14.
    • (2009) Am. Nat. , vol.174
    • Otto, S.P.1
  • 52
    • 0030871021 scopus 로고    scopus 로고
    • The evolution of recombination: removing the limits to natural selection
    • Otto, S. P., and N. H. Barton. 1997. The evolution of recombination: removing the limits to natural selection. Genetics 147:879-906.
    • (1997) Genetics , vol.147 , pp. 879-906
    • Otto, S.P.1    Barton, N.H.2
  • 53
    • 0028229790 scopus 로고
    • A ruby in the rubbish: Beneficial mutations, deleterious mutations and the evolution of sex
    • Peck, J. R. 1994. A ruby in the rubbish: Beneficial mutations, deleterious mutations and the evolution of sex. Genetics 137:597-606.
    • (1994) Genetics , vol.137 , pp. 597-606
    • Peck, J.R.1
  • 54
    • 0032743011 scopus 로고    scopus 로고
    • Free content genetic polarization: unifying theories for the adaptive significance of recombination
    • Rice, W. R. 1999. Free content genetic polarization: unifying theories for the adaptive significance of recombination. J. Evol. Biol. 12:1047-1049.
    • (1999) J. Evol. Biol. , vol.12 , pp. 1047-1049
    • Rice, W.R.1
  • 55
    • 33746430558 scopus 로고    scopus 로고
    • The Hill-Robertson effect and the evolution of recombination
    • Roze, D., and N. H. Barton. 2006. The Hill-Robertson effect and the evolution of recombination. Genetics 173:1793-1811.
    • (2006) Genetics , vol.173 , pp. 1793-1811
    • Roze, D.1    Barton, N.H.2
  • 57
    • 0036218367 scopus 로고    scopus 로고
    • A comprehensive model of mutations affecting fitness and interferences for Arabidopsis thaliana
    • Shaw, F. H., C. J. Geyer, and R. G. Shaw. 2002. A comprehensive model of mutations affecting fitness and interferences for Arabidopsis thaliana. Evolution 56:453-463.
    • (2002) Evolution , vol.56 , pp. 453-463
    • Shaw, F.H.1    Geyer, C.J.2    Shaw, R.G.3
  • 58
    • 0017683085 scopus 로고
    • The effect of a selected locus on linked neutral loci
    • Thomson, G. 1977. The effect of a selected locus on linked neutral loci. Genetics 85:753-788.
    • (1977) Genetics , vol.85 , pp. 753-788
    • Thomson, G.1
  • 60
    • 0001771498 scopus 로고
    • Evolution in Mendelian populations
    • Wright, S. 1931. Evolution in Mendelian populations. Genetics 16:97-159.
    • (1931) Genetics , vol.16 , pp. 97-159
    • Wright, S.1
  • 61
    • 77249137355 scopus 로고    scopus 로고
    • Rate of adaptation of large populations
    • P. Pontarotti, ed. Springer-Verlag, Berlin
    • Yu, F., and A. M. Etheridge. 2008. Rate of adaptation of large populations. Pp. 3-27, in P. Pontarotti, ed. Evolutionary Biology from Concept to Application. Springer-Verlag, Berlin.
    • (2008) Evolutionary Biology from Concept to Application , pp. 3-27
    • Yu, F.1    Etheridge, A.M.2
  • 62
    • 77954027300 scopus 로고    scopus 로고
    • The fixation probability of two competing beneficial mutations
    • Yu, F., and A. M. Etheridge. 2010. The fixation probability of two competing beneficial mutations. Theor. Popul. Biol. 78:36-45.
    • (2010) Theor. Popul. Biol. , vol.78 , pp. 36-45
    • Yu, F.1    Etheridge, A.M.2
  • 63
    • 77953828642 scopus 로고    scopus 로고
    • Asymptotic behavior of the rate of adaptation
    • Yu, F., A. M. Etheridge, and C. Cuthbertson. 2010. Asymptotic behavior of the rate of adaptation. Ann. Appl. Probab. 20:978-1004.
    • (2010) Ann. Appl. Probab. , vol.20 , pp. 978-1004
    • Yu, F.1    Etheridge, A.M.2    Cuthbertson, C.3


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