Toward a realistic model of mutations affecting fitness

Evolution

Volumn 57, Issue 3, 2003, Pages 683-685

  Keightley, Peter D ^a   Lynch, Michael ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Arabidopsis; Mutation; Mutation accumulation; Mutational effects distribution; Statistical inference

Indexed keywords

FITNESS; MUTATION;

ANIMALIA; ARABIDOPSIS; EMBRYOPHYTA;

EID: 0037360124     PISSN: 00143820     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0014-3820.2003.tb01561.x     Document Type: Short Survey

References (34)

1. Bataillon, T. 2000. Estimation of spontaneous genome-wide mutation rate parameters: whither beneficial mutations? Heredity 84:497-501.
2. Camara, M. D., and M. Pigliucci. 1999. Mutational contributions to genetic variance-covariance matrices: an experimental approach using induced mutations in Arabidopsis thaliana. Evolution 53:1692-1703.
3. Chavarrias, D., C. López-Fanjul, and A. García-Dorado. 2001. The rate of mutation and the homozygous and heterozygous mutational effects for competitive viability: a long-term experiment with Drosophila melanogaster. Genetics 158:681-693.
4. Elena, S. F., and R. E. Lenski. 1997. Test of synergistic interactions among deleterious mutations in bacteria. Nature 390:395-398.
5. Eyre-Walker, A., P. D. Keightley, N. G. C. Smith, and D. J. Gaffney. 2002. Quantifying the slightly deleterious model of molecular evolution. Mol. Biol. Evol. 19:2142-2149.
6. Fay, J., G. J. Wycoff, and C.-I. Wu. 2001. Positive and negative selection on the human genome. Genetics 158:1227-1234.
7. Frankham, R. 1990. Are responses to artificial selection for reproductive fitness characters consistently asymmetrical? Genet. Res. 56:35-42.
8. Fry, J. D., P. D. Keightley, S. L. Heinsohn, and S. V. Nuzhdin. 1999. New estimates of rates and effects of mildly deleterious mutation in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 96:574-579.
9. García-Dorado, A. 1997. The rate and effects distribution of viable mutation in Drosophila: Minimum distance estimation. Evolution 51:1130-1139.
10. García-Dorado, A., C. López-Fanjul, and A. Caballero. 1999. Properties of spontaneous mutations affecting quantitative traits. Genet. Res. 74:341-350.
11. Keightley, P. D. 1994. The distribution of mutation effects on viability in Drosophila melanogaster. Genetics 138:1315-1322.
12. Keightley, P. D., and A. Caballero 1997. Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 94:3823-3827.
13. Keightley, P. D., and A. Eyre-Walker. 1999. Terumi Mukai and the riddle of deleterious mutation rates. Genetics 153:515-523.
14. Keightley, P. D., and O. Ohnishi. 1998. EMS-induced polygenic mutation rates for nine quantitative characters in Drosophila melanogaster. Genetics 148:753-766.
15. Keightley, P. D., E. K. Davies, A. D. Peters, and R. G. Shaw. 2000. Properties of EMS-induced mutations affecting life history traits in Caenorhabditis elegans and inferences about bivariate distributions of mutation effects. Genetics 156:143-154.
16. Keightley, P. D., and T. A. Bataillon. 2000. Multi-generation maximum likelihood analysis applied to mutation accumulation experiments in Caenorhabditis elegans. Genetics 154:1193-1201.
17. Kibota, T. T., and M. Lynch. 1996. Estimate of the genomic mutation rate deleterious to overall fitness in E. coli. Nature 381:694-696.
18. Li, W.-H. 1997. Molecular Evolution. Sinauer, Sunderland, MA.
19. Lynch, M., J. Blanchard, D. Houle, T. Kibota, S. Schultz, L. Vassilieva, and J. Willis. 1999. Perspective: spontaneous deleterious mutation. Evolution 53:645-663.
20. Mackay, T. F. C., R. Lyman, and M. S. Jackson 1992. Effects of P elements on quantitative traits in Drosophila melanogaster. Genetics 130:315-332.
21. Mitchell, J. A., and M. J. Simmons. 1977. Fitness effects of EMS-induced mutations on the X chromosome of Drosophila melanogaster. II. Hemizygous fitness effects. Genetics 87:775-783.
22. Mukai, T. 1970. Viability mutations induced by ethyl methanesulfonate in Drosophila melanogaster. Genetics 65:335-348.
23. Ohnishi, O. 1977. Spontaneous and ethyl methanesulfonate-induced mutations controlling viability in Drosophila melanogaster. II. Homozygous effect of polygenic mutations. Genetics 87:529-545.
24. Ohta, T. 1995. Synonymous and nonsynonymous substitutions in mammalian genes and the nearly neutral theory. J. Mol. Evol. 40:56-63.
25. Schultz, S. T., M. Lynch, and J. H. Willis. 1999. Spontaneous deleterious mutation in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 96:11393-11398.
26. Shaw, F. J., C. J. Geyer, and R. G. Shaw. 2002. A comprehensive model of mutations affecting fitness and inferences for Arabidopsis thaliana. Evolution 56:453-463.
27. Shaw, R. G., D. L. Byers, and E. Darmo. 2000. Spontaneous mutational effects on reproductive traits of Arabidopsis thaliana. Genetics 155:369-378.
28. Temin, R. G. 1978. Partial dominance of EMS-induced mutations affecting viability in Drosophila melanogaster. Genetics 89:315-340.
29. Vassilieva, L. L., and M. Lynch, 1999. The rate of spontaneous mutation for life-history traits in Caenorhabditis elegans. Genetics 151:119-129.
30. Vassilieva, L. L., A. M. Hook, and M. Lynch. 2000. The fitness effects of spontaneous mutations in Caenorhabditis elegans. Evolution 54:1234-1246.
31. Wloch, D. M., K. Szafraniec, R. H. Borts, and R. Korona. 2001. Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae. Genetics 159:441-452.
32. Wright, S. I., B. Lauga, and D. Charlesworth. 2002. Rates and patterns of molecular evolution in inbred and outbred Arabidopsis. Mol. Biol. Evol. 19:1407-1420.
33. Yang, H. P., A. Y. Tanikawa, W. A. Van Voorhies, J. C. Silva, and A. S. Kondrashov. 2001. Whole-genome effects of ethyl methanesulfonate-induced mutation on nine quantitative traits in outbred Drosophila melanogaster. Genetics 157:1257-1265.
34. Zeyl, C., and J. A. G. M. DeVisser. 2001. Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiae. Genetics 157:53-61.