Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rγnull mice

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Jaiswal, Smita ^a   Pearson, Todd ^a   Friberg, Heather ^a   Shultz, Leonard D ^b   Greiner, Dale L ^a   Rothman, Alan L ^a   Mathew, Anuja ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; GAMMA INTERFERON; HLA A2 ANTIGEN; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA; PEPTIDE; RNA;

ANIMAL CELL; ANTIBODY DETECTION; ARTICLE; BONE MARROW; CELLULAR IMMUNITY; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; DISEASE PREDISPOSITION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; IMMUNITY; LIVER; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PROTEIN SECRETION; SPLEEN; T LYMPHOCYTE; UMBILICAL CORD BLOOD; VIRUS DETECTION; VIRUS LOAD; VIRUS STRAIN; ANIMAL; CHEMISTRY; CYTOLOGY; FETUS BLOOD; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; VIROLOGY;

ANIMALIA; DENGUE VIRUS; MUS;

ANIMALS; DENGUE; DENGUE VIRUS; FETAL BLOOD; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HLA-A2 ANTIGEN; HUMANS; INTERLEUKIN-2; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; PEPTIDES; RNA;

EID: 70350031633     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007251     Document Type: Article

References (46)

1. Gubler DJ (1998) Dengue and dengue hemorrhagic fever. Clin Microbiol Rev 11: 480-496.
2. Gubler DJ, Clark GG (1995) Dengue/dengue hemorrhagic fever: the emergence of a global health problem. Emerging Infectious Diseases 1: 55.
3. Burke DS, Nisalak A, Johnson DE, Scott RM (1988) A prospective study of dengue infections in Bangkok. American Journal of Tropical Medicine and Hygiene 38: 172-180.
4. Halstead SB (1989) Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Reviews of Infectious Diseases 11: S830-S839.
5. Kurane I, Rothman AL, Livingston PG, Green S, Gagnon SJ, et al. (1994) Immunopathologic mechanisms of dengue hemorrhagic fever and dengue shock syndrome. Archives of Virology 9: 59-64.
6. Halstead SB, Shotwell H, Casals J (1973) Studies on the pathogenesis of dengue infection in monkeys. I. Clinical laboratory responses to primary infection. Journal of Infectious Diseases 128: 7-14.
7. Eckels KH, Dubois DR, Summers PL, Schlesinger JJ, Shelly M, et al. (1994) Immunization of monkeys with baculovirus-dengue type-4 recombinants containing envelope and nonstructural proteins: evidence of priming and partial protection. Am J Trop Med Hyg 50: 472-478.
8. An J, Kimura-Kuroda J, Hirabayashi Y, Yasui K (1999) Development of a novel mouse model for dengue virus infection. Virology 263: 70-77.
9. Lin YL, Liao CL, Chen LK, Yeh CT, Liu CI, et al. (1998) Study of Dengue virus infection in SCID mice engrafted with human K562 cells. J Virol 72: 9729-9737.
10. Shresta S, Kyle JL, Snider HM, Basavapatna M, Beatty PR, et al. (2004) Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J Virol 78: 2701-2710.
11. Shresta S, Sharar KL, Prigozhin DM, Beatty PR, Harris E (2006) Murine model for dengue virus-induced lethal disease with increased vascular permeability. J Virol 80: 10208-10217.
12. Shresta S, Sharar KL, Prigozhin DM, Snider HM, Beatty PR, et al. (2005) Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice. J Immunol 175: 3946-3954.
13. Johnson AJ, Roehrig JT (1999) New mouse model for dengue virus vaccine testing. Journal of Virology 73: 783-786.
14. Chen HC, Hofman FM, Kung JT, Lin YD, Wu-Hsieh BA (2007) Both virus and tumor necrosis factor alpha are critical for endothelium damage in a mouse model of dengue virus-induced hemorrhage. J Virol 81: 5518-5526.
15. Wu SJ, Hayes CG, Dubois DR, Windheuser MG, Kang YH, et al. (1995) Evaluation of the severe combined immunodeficient (SCID) mouse as an animal model for dengue viral infection. Am J Trop Med Hyg 52: 468-476.
16. Mota J, Rico-Hesse R (2009) Humanized mice show clinical signs of dengue fever according to infecting virus genotype. J Virol.
17. Bente DA, Melkus MW, Garcia JV, Rico-Hesse R (2005) Dengue fever in humanized NOD/SCID mice. J Virol 79: 13797-13799.
18. Kuruvilla JG, Troyer RM, Devi S, Akkina R (2007) Dengue virus infection and immune response in humanized RAG2(-/-)gamma(c)(-/-) (RAG-hu) mice. Virology 369: 143-152.
19. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, et al. (2005) Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 174: 6477-6489.
20. Shultz LD, Ishikawa F, Greiner DL (2007) Humanized mice in translational biomedical research. Nat Rev Immunol 7: 118-130.
21. Watanabe S, Terashima K, Ohta S, Horibata S, Yajima M, et al. (2007) Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses. Blood 109: 212-218.
22. Greiner DL, Hesselton RA, Shultz LD (1998) SCID mouse models of human stem cell engraftment. Stem Cells 16: 166-177.
23. Ishikawa F, Livingston AG, Wingard JR, Nishikawa S, Ogawa M (2002) An assay for long-term engrafting human hematopoietic cells based on newborn NOD/SCID/beta2-microglobulin(null) mice. Exp Hematol 30: 488-494.
24. Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, et al. (2005) Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice. Blood 106: 1565-1573.
25. Bashyam HS, Green S, Rothman AL (2006) Dengue virus-reactive CD8+ T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes. J Immunol 176: 2817-2824.
26. Kurane I, Kontny U, Janus J, Ennis FA (1990) Dengue-2 virus infection of human mononuclear cell lines and establishment of persistent infections. Archives of Virology 110: 91-101.
27. Cologna R, Armstrong PM, Rico-Hesse R (2005) Selection for virulent dengue viruses occurs in humans and mosquitoes. J Virol 79: 853-859.
28. Lin YW, Wang KJ, Lei HY, Lin YS, Yeh TM, et al. (2002) Virus replication and cytokine production in dengue virus-infected human B lymphocytes. J Virol 76: 12242-12249.
29. Sanchez V, Hessler C, DeMonfort A, Lang J, Guy B (2006) Comparison by flow cytometry of immune changes induced in human monocyte-derived dendritic cells upon infection with dengue 2 live-attenuated vaccine or 16681 parental strain. FEMS Immunol Med Microbiol 46: 113-123.
30. Tassaneetrithep B, Burgess TH, Granelli-Piperno A, Trumpfheller C, Finke J, et al. (2003) DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med 197: 823-829.
31. Bray M, Men R, Tokimatsu I, Lai CJ (1998) Genetic determinants responsible for acquisition of dengue type 2 virus mouse neurovirulence. J Virol 72: 1647-1651.
32. Macchiarini F, Manz MG, Palucka AK, Shultz LD (2005) Humanized mice: are we there yet? J Exp Med 202: 1307-1311.
33. Traggiai E, Chicha L, Mazzucchelli L, Bronz L, Piffaretti JC, et al. (2004) Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 304: 104-107.
34. Woodland RT, Fox CJ, Schmidt MR, Hammerman PS, Opferman JT, et al. (2007) Multiple signaling pathways promote B lymphocyte stimulator (BLyS)-dependent B cell growth and survival. Blood.
35. Woodland RT, Schmidt MR, Thompson CB (2006) BLyS and B cell homeostasis. Semin Immunol 18: 318-326.
36. Diamond MS, Roberts TG, Edgil D, Lu B, Ernst J, et al. (2000) Modulation of dengue virus infection in human cells by alpha, beta, and gamma interferons. Journal of Virology 74: 4957-4966.
37. Diamond MS, Harris E (2001) Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism. Virology 289: 297-311.
38. Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, et al. (2006) Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat Med 12: 1316-1322.
39. Pearson T, Greiner DL, Shultz LD (2008) Humanized SCID mouse models for biomedical research. Curr Top Microbiol Immunol 324: 25-51.
40. Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, et al. (2007) In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice. Diabetes 56: 2551-2560.
41. Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, et al. (2006) HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol 176: 3257-3265.
42. Kurane I, Zeng L, Brinton MA, Ennis FA (1998) Definition of an epitope on NS3 recognized by human CD4+ cytotoxic T lymphocyte clones cross-reactive for dengue virus types 2, 3, and 4. Virology 240: 169-174.
43. Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, et al. (1997) Early clinical and laboratory indicators of acute dengue illness. JID 176: 313-321.
44. Vaughn DW, Green S, Kalayanarooj S, Innis BL, Nimmannitya S, et al. (1997) Dengue in the early febrile phase: viremia and antibody responses. JID 176: 322-330.
45. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV (1992) Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30: 545-551.
46. Armstrong PM, Rico-Hesse R (2003) Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti. Am J Trop Med Hyg 68: 539-544.