Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Becker, Pablo D ^a   Legrand, Nicolas ^b   van Geelen, Caroline M M ^c   Noerder, Miriam ^a   Huntington, Nicholas D ^d,e   Lim, Annick ^a   Yasuda, Etsuko ^c,g   Diehl, Sean A ^b,g   Scheeren, Ferenc A ^b,h   Ott, Michael ^f   Weijer, Kees ^b   Wedemeyer, Heiner ^f   di Santo, Jamesdi P ^d,e   Beaumont, Tim ^c   Guzman, Carlos A ^a   Spits, Hergen ^b,c  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c AIMM Therapeutics   (Netherlands)

^d INSTITUT PASTEUR   (France)

^e INSTITUT PASTEUR   (France)

^f INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^g UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^h STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD19 ANTIGEN; CD27 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD40 LIGAND; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 21; RECOMBINANT HEPATITIS B VACCINE; TETANUS TOXOID;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTICLE; B CELL LYMPHOMA 6 GENE; B LYMPHOCYTE; BCL XL GENE; CELL CLONE; CELL IMMORTALIZATION; CELL SELECTION; CONTROLLED STUDY; CULTURE MEDIUM; FETUS; GENE; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE SYSTEM; IMMUNOGLOBULIN PRODUCTION; LIVER PARENCHYMA; MOUSE; NONHUMAN;

ANIMALS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; CELL SEPARATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNE SYSTEM; IMMUNOGLOBULIN M; MICE; MICE, INBRED BALB C;

MURINAE; MUS;

EID: 78049251370     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013137     Document Type: Article

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