NOD/SCID mice engineered to express human IL-3, GM-CSF and steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration

Leukemia

Volumn 18, Issue 2, 2004, Pages 341-347

  Nicolini, F E ^a   Cashman, J D ^a   Hogge, D E ^a,b   Humphries, R K ^a,b   Eaves, C J ^a,b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Growth factors; Human hematopoiesis; Immunodeficient mice; Transgenic

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; STEEL FACTOR;

ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL REGENERATION; CLONOGENESIS; CONTROLLED STUDY; ERYTHROPOIESIS; FETUS LIVER; GENE EXPRESSION; GENETIC ENGINEERING; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE DEFICIENCY; IN VIVO STUDY; LIVER CELL; LYMPHOPOIESIS; MOUSE; MOUSE STRAIN; MYELOPOIESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SCID MOUSE; STEM CELL TRANSPLANTATION;

EID: 1242329864     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403222     Document Type: Article

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