Lentiviral vector delivery of human interleukin-7 (hiL-7) to human immune system (HIS) mice expands T lymphocyte populations

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  O'Connell, Ryan M ^a   Balazs, Alejandro B ^a   Rao, Dinesh S ^a,b   Kivork, Christine ^a   Yang, Lili ^a   Baltimore, David ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7; LENTIVIRUS VECTOR; PROTEIN BCL 2; BCL2 PROTEIN, MOUSE; ONCOPROTEIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; ENGRAFTMENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; SINGLE DRUG DOSE; SPLEEN; T LYMPHOCYTE; VIRUS LOAD; ANIMAL; CELL COUNT; CELL PROLIFERATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENE TRANSFER; GENE VECTOR; GENETICS; HOMEOSTASIS; HUMAN; IMMUNOLOGY; LENTIVIRINAE; METABOLISM;

MUS;

ANIMALS; CELL COUNT; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIV INFECTIONS; HOMEOSTASIS; HUMANS; INTERLEUKIN-7; LENTIVIRUS; MICE; PROTO-ONCOGENE PROTEINS; SPLEEN; T-LYMPHOCYTES; VIRAL LOAD;

EID: 77957773125     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012009     Document Type: Article

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