CD47 (Integrin-associated Protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

Journal of Experimental Medicine

Volumn 194, Issue 4, 2001, Pages 541-549

  Blazar, B R ^a   Lindberg, F P ^a   Ingulli, E ^a   Panoskaltsis Mortari, A ^a   Oldenborg, P A ^a   Iizuka, K ^a   Yokoyama, W M ^a   Taylor, P A ^a  

^a UNIV OF MINNESOTA HOSP AND CLINIC   (United States)

Author keywords

Immune tolerance; In vivo animal models; Stem cells; T cells; Transplantation

Indexed keywords

CD47 ANTIGEN;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC CELL; IMMUNE SYSTEM; LEUKOCYTE MIGRATION; MACROPHAGE; MACROPHAGE FUNCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD47; BONE MARROW CELLS; CARRIER PROTEINS; CELL TRANSPLANTATION; DENDRITIC CELLS; DOWN-REGULATION; GRAFT VS HOST DISEASE; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, SCID; MODELS, ANIMAL; RECEPTORS, IMMUNOLOGIC;

EID: 0035920515     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.4.541     Document Type: Article

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5. Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells
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14. Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
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16. Requirement for membrane lymphotoxin in natural killer cell development
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18. Kupffer cell engraftment across the major histocompatibility barrier in mice: Bone marrow origin, class II antigen expression, and antigen-presenting capacity
19. CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPα 1
20. Natural killer cells. Right-side-up and up-side-down NK-cell receptors
21. Immune inhibitory receptors
22. Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin