Roles and mechanisms of MicroRNAs in pancreatic cancer

World Journal of Surgery

Volumn 35, Issue 8, 2011, Pages 1725-1731

  Zhang, Lidong ^a   Jamaluddin, Md Saha ^a   Weakley, Sarah M ^a   Yao, Qizhi ^a   Chen, Changyi ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

CANCER INVASION; CELL PROLIFERATION; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MORTALITY; PANCREAS TUMOR; PROGNOSIS; REVIEW; SURVIVAL RATE;

CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; PROGNOSIS; SURVIVAL RATE;

EID: 80051572484     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-010-0952-z     Document Type: Article

References (69)

1. MJ Hayat N Howlader ME Reichman, et al. 2007 Cancer statistics, trends, and multiple primary cancer analyses from the surveillance, epidemiology, and end results (SEER) program Oncologist 12 20 37 17227898 10.1634/theoncologist. 12-1-20 (Pubitemid 46143500)
2. G Sergeant H Vankelecom L Gremeaux, et al. 2009 Role of cancer stem cells in pancreatic ductal adenocarcinoma Nat Rev Clin Oncol 6 580 586 19687789 10.1038/nrclinonc.2009.127
3. V Ambros 2004 The functions of animal microRNAs Nature 431 350 355 15372042 10.1038/nature02871 1:CAS:528:DC%2BD2cXnsFaiu7g%3D (Pubitemid 39265675)
4. RI Gregory TP Chendrimada N Cooch, et al. 2005 Human RISC couples microRNA biogenesis and posttranscriptional gene silencing Cell 123 631 640 16271387 10.1016/j.cell.2005.10.022 1:CAS:528:DC%2BD2MXht1yktrjN (Pubitemid 41608466)
5. M Li C Marin-Muller U Bharadwaj, et al. 2009 MicroRNAs: control and loss of control in human physiology and disease World J Surg 33 667 684 19030926 10.1007/s00268-008-9836-x
6. KM Nelson GJ Weiss 2008 MicroRNAs and cancer: past, present, and potential future Mol Cancer Ther 7 3655 3660 19074842 10.1158/1535-7163.MCT-08- 0586 1:CAS:528:DC%2BD1cXhsV2iurjF
7. A Esquela-Kerscher FJ Slack 2006 Oncomirs-microRNAs with a role in cancer Nat Rev Cancer 6 259 269 16557279 10.1038/nrc1840 1:CAS:528: DC%2BD28XivVyqtrs%3D
8. DP Bartel 2004 MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 281 297 14744438 10.1016/S0092-8674(04)00045-5 1:CAS:528: DC%2BD2cXhtVals7o%3D (Pubitemid 38167318)
9. EJ Lee Y Gusev J Jiang, et al. 2007 Expression profiling identifies microRNA signature in pancreatic cancer Int J Cancer 120 1046 1054 17149698 10.1002/ijc.22394 1:CAS:528:DC%2BD2sXhsVWhsrc%3D (Pubitemid 46214304)
10. AE Szafranska TS Davison J John, et al. 2007 MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma Oncogene 26 4442 4452 17237814 10.1038/sj.onc.1210228 1:CAS:528:DC%2BD2sXntVCju7w%3D (Pubitemid 47014466)
11. M Bloomston WL Frankel F Petrocca, et al. 2007 MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis JAMA 297 1901 1908 17473300 10.1001/jama.297.17.1901 1:CAS:528:DC%2BD2sXkvFKru7g%3D (Pubitemid 46707844)
12. Y Zhang M Li H Wang, et al. 2009 Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis World J Surg 33 698 709 19030927 10.1007/s00268-008-9833-0
13. C Roldo E Missiaglia JP Hagan, et al. 2006 MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior J Clin Oncol 24 4677 4684 16966691 10.1200/JCO.2005.05.5194 1:CAS:528:DC%2BD28XhtFynsr3M (Pubitemid 46630931)
14. I De Martino R Visone M Fedele, et al. 2009 Regulation of microRNA expression by HMGA1 proteins Oncogene 28 1432 1442 19169275 10.1038/onc.2008.495
15. M Dillhoff J Liu W Frankel, et al. 2008 MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival J Gastrointest Surg 12 2171 2176 18642050 10.1007/s11605-008-0584-x
16. AM Duursma M Kedde M Schrier, et al. 2008 miR-148 targets human DNMT3b protein coding region RNA 14 872 877 18367714 10.1261/rna.972008 1:CAS:528:DC%2BD1cXls1Wrtrg%3D (Pubitemid 351574909)
17. N Habbe JB Koorstra JT Mendell, et al. 2009 MicroRNA miR-155 is a biomarker of early pancreatic neoplasia Cancer Biol Ther 8 340 346 19106647 10.4161/cbt.8.4.7338 1:CAS:528:DC%2BD1MXotV2qtLs%3D
18. BS Haflidadottir K Bergsteinsdottir C Praetorius, et al. 2010 miR-148 regulates Mitf in melanoma cells PLoS One 5 e11574 20644734 10.1371/journal. pone.0011574
19. X Huang L Ding KL Bennewith, et al. 2009 Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation Mol Cell 35 856 867 19782034 10.1016/j.molcel.2009.09.006 1:CAS:528:DC%2BD1MXhsVChsrzI
20. JH Hwang J Voortman E Giovannetti, et al. 2010 Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer PLoS One 5 e10630 20498843 10.1371/journal.pone.0010630
21. Y Li TG Vandenboom Z Wang, et al. 2010 miR-146a suppresses invasion of pancreatic cancer cells Cancer Res 70 1486 1495 20124483 10.1158/0008-5472.CAN- 09-2792 1:CAS:528:DC%2BC3cXhvFaksLk%3D
22. LF Lu MP Boldin A Chaudhry, et al. 2010 Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses Cell 142 914 929 20850013 10.1016/j.cell.2010.08.012 1:CAS:528:DC%2BC3cXhtFyitbzK
23. R Luthra RR Singh MG Luthra, et al. 2008 MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers Oncogene 27 6667 6678 18663355 10.1038/onc.2008.256 1:CAS:528:DC%2BD1cXhtlegurfO
24. AK Nagaraja CJ Creighton Z Yu, et al. 2010 A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer Mol Endocrinol 24 447 463 20081105 10.1210/me.2009-0295 1:CAS:528:DC%2BC3cXhslejsrc%3D
25. SM Park AB Gaur E Lengyel, et al. 2008 The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 Genes Dev 22 894 907 18381893 10.1101/gad.1640608 1:CAS:528: DC%2BD1cXksVGktL4%3D (Pubitemid 351482843)
26. Y Pekarsky GA Calin R Aqeilan 2005 Chronic lymphocytic leukemia: molecular genetics and animal models Curr Top Microbiol Immunol 294 51 70 16323427 10.1007/3-540-29933-5-4 1:CAS:528:DC%2BD2MXhtlamsr%2FJ (Pubitemid 41491250)
27. Y Tsukamoto C Nakada T Noguchi, et al. 2010 MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta Cancer Res 70 2339 2349 20215506 10.1158/0008-5472.CAN-09-2777 1:CAS:528:DC%2BC3cXjtFygtL8%3D
28. H Xia Y Qi SS Ng, et al. 2009 MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells Biochem Biophys Res Commun 380 205 210 19135980 10.1016/j.bbrc.2008.12.169 1:CAS:528:DC%2BD1MXitlWqtLw%3D
29. CZ Zhang JX Zhang AL Zhang, et al. 2010 MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma Mol Cancer 9 229 20813046 10.1186/1476-4598-9-229
30. Y Ma S Yu W Zhao, et al. 2010 miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2 Cancer Lett 298 150 158 20638779 10.1016/j.canlet.2010.06.012 1:CAS:528: DC%2BC3cXhtlSgt7nK
31. T Moriyama K Ohuchida K Mizumoto, et al. 2009 MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance Mol Cancer Ther 8 1067 19435867 10.1158/1535-7163.MCT-08-0592 1:CAS:528:DC%2BD1MXmtlGqsLs%3D
32. HJ Yan JX Wu WS Liu, et al. 2010 MicroRNA-20a Overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells Hum Gene Ther 21 1723 1734 20583868 10.1089/hum.2010.061 1:CAS:528:DC%2BC3cXhsFCru73K
33. S Yekta IH Shih DP Bartel 2004 MicroRNA-directed cleavage of HOXB8 mRNA Science 304 594 596 15105502 10.1126/science.1097434 1:CAS:528: DC%2BD2cXjt1Crsr0%3D (Pubitemid 38541919)
34. S Yu Z Lu C Liu, et al. 2010 miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer Cancer Res 70 6015 6025 20610624 10.1158/0008-5472.CAN-09-4531 1:CAS:528:DC%2BC3cXovVamsro%3D
35. Z Chun-Zhi H Lei Z An-Ling, et al. 2010 MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN BMC Cancer 10 367 20618998 10.1186/1471-2407-10-367
36. CM Croce 2009 Causes and consequences of microRNA dysregulation in cancer Nat Rev Genet 10 704 714 19763153 10.1038/nrg2634 1:CAS:528:DC%2BD1MXhtFCqurjE
37. W Shi NM Alajez C Bastianutto, et al. 2010 Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer Int J Cancer 126 2036 2048 19739117 1:CAS:528:DC%2BC3cXisFemtb0%3D
38. T Greither LF Grochola A Udelnow, et al. 2010 Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival Int J Cancer 126 73 80 19551852 10.1002/ijc.24687 1:CAS:528: DC%2BD1MXhsVamtL7I
39. PA Gregory AG Bert EL Paterson, et al. 2008 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Nat Cell Biol 10 593 601 18376396 10.1038/ncb1722 1:CAS:528: DC%2BD1cXltl2is7c%3D (Pubitemid 351627379)
40. M Gironella M Seux MJ Xie, et al. 2007 Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development Proc Natl Acad Sci USA 104 16170 16175 17911264 10.1073/pnas.0703942104 1:CAS:528:DC%2BD2sXhtF2hu7fK (Pubitemid 350099380)
41. B Wang SH Hsu S Majumder, et al. 2010 TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3 Oncogene 29 1787 1797 20023698 10.1038/onc.2009.468 1:CAS:528:DC%2BD1MXhsFyhsLvO
42. K Wurz RL Garcia BA Goff, et al. 2010 MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma: relationship to CDKN1B, CDKNIC and overall survival Genes Chromosomes Cancer 49 577 584 20461750 1:CAS:528:DC%2BC3cXlvVGlt7s%3D
43. ST Mees WA Mardin C Wendel, et al. 2010 EP300-a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas Int J Cancer 126 114 124 19569050 10.1002/ijc.24695 1:CAS:528:DC%2BD1MXhsVamtL7L
44. ST Mees WA Mardin S Sielker, et al. 2009 Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas Ann Surg Oncol 16 2339 2350 19475450 10.1245/s10434-009-0531-4
45. T Liu H Tang Y Lang, et al. 2009 MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin Cancer Lett 273 233 242 18789835 10.1016/j.canlet.2008.08.003 1:CAS:528:DC%2BD1cXhsV2gtbrF
46. SU Mertens-Talcott S Chintharlapalli X Li, et al. 2007 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells Cancer Res 67 11001 11011 18006846 10.1158/0008-5472.CAN-07-2416 1:CAS:528:DC%2BD2sXhtlSlsLrL (Pubitemid 350145930)
47. S Chintharlapalli S Papineni M Abdelrahim, et al. 2009 Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3, 11-dioxo-18beta-olean-1, 12-dien-30-oate in colon cancer cells Int J Cancer 125 1965 1974 19582879 10.1002/ijc.24530 1:CAS:528:DC%2BD1MXhtVGisr7N
48. IK Guttilla BA White 2009 Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells J Biol Chem 284 23204 23216 19574223 10.1074/jbc.M109.031427 1:CAS:528:DC%2BD1MXhtVWqtrnJ
49. D Bhaumik GK Scott S Schokrpur, et al. 2008 Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells Oncogene 27 5643 5647 18504431 10.1038/onc.2008.171 1:CAS:528:DC%2BD1cXhtFant7%2FE
50. DR Hurst MD Edmonds GK Scott, et al. 2009 Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis Cancer Res 69 1279 1283 19190326 10.1158/0008-5472.CAN-08-3559 1:CAS:528:DC%2BD1MXhslygu7c%3D
51. SL Lin A Chiang D Chang, et al. 2008 Loss of mir-146a function in hormone-refractory prostate cancer RNA 14 417 424 18174313 10.1261/rna.874808 1:CAS:528:DC%2BD1cXivFaqs7o%3D (Pubitemid 351397806)
52. F Wang X Xue J Wei, et al. 2010 hsa-miR-520 h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations Br J Cancer 103 567 574 20628378 10.1038/sj.bjc.6605724 1:CAS:528: DC%2BC3cXhtVSmtb%2FF
53. M Korpal ES Lee G Hu, et al. 2008 The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2 J Biol Chem 283 14910 14914 18411277 10.1074/jbc.C800074200 1:CAS:528:DC%2BD1cXmtlynsbc%3D
54. EJ Nam H Yoon SW Kim, et al. 2008 MicroRNA expression profiles in serous ovarian carcinoma Clin Cancer Res 14 2690 2695 18451233 10.1158/1078-0432.CCR- 07-1731 1:CAS:528:DC%2BD1cXlsV2qtL8%3D
55. L Adam M Zhong W Choi, et al. 2009 miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy Clin Cancer Res 15 5060 5072 19671845 10.1158/1078-0432.CCR-08-2245 1:CAS:528:DC%2BD1MXpvFeis70%3D
56. A Li N Omura SM Hong, et al. 2010 Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels Cancer Res 70 5226 5237 20551052 10.1158/0008-5472.CAN-09-4227 1:CAS:528:DC%2BC3cXot1Wlu74%3D
57. E Giovannetti N Funel GJ Peters, et al. 2010 MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity Cancer Res 70 4528 4538 20460539 10.1158/0008-5472.CAN-09-4467 1:CAS:528:DC%2BC3cXmslWgt7Y%3D
58. X Hu DM Macdonald PC Huettner, et al. 2009 A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer Gynecol Oncol 114 457 464 19501389 10.1016/j.ygyno.2009.05.022 1:CAS:528:DC%2BD1MXptlSrt70%3D
59. EL Paterson N Kolesnikoff PA Gregory, et al. 2008 The microRNA-200 family regulates epithelial to mesenchymal transition Sci World J 8 901 904 1:CAS:528:DC%2BD1cXht1ygt7%2FP
60. S Ali A Ahmad S Banerjee, et al. 2010 Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF Cancer Res 70 3606 3617 20388782 10.1158/0008-5472.CAN-09-4598 1:CAS:528:DC%2BC3cXltlens74%3D
61. TC Chang EA Wentzel OA Kent, et al. 2007 Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis Mol Cell 26 745 752 17540599 10.1016/j.molcel.2007.05.010 1:CAS:528:DC%2BD2sXnt1Cquro%3D (Pubitemid 46856245)
62. N Raver-Shapira E Marciano E Meiri, et al. 2007 Transcriptional activation of miR-34a contributes to p53-mediated apoptosis Mol Cell 26 731 743 17540598 10.1016/j.molcel.2007.05.017 1:CAS:528:DC%2BD2sXnt1Cqur0%3D (Pubitemid 46856247)
63. D Lodygin V Tarasov A Epanchintsev, et al. 2008 Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer Cell Cycle 7 2591 2600 18719384 10.4161/cc.7.16.6533 1:CAS:528:DC%2BD1cXht1elsbnO
64. Q Ji X Hao M Zhang, et al. 2009 MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells PLoS One 4 e6816 19714243 10.1371/journal.pone. 0006816
65. J Yu K Ohuchida K Mizumoto, et al. 2010 MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation Mol Cancer 9 169 20579395 10.1186/1476-4598-9-169
66. AE Szafranska M Doleshal HS Edmunds, et al. 2008 Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissues Clin Chem 54 1716 1724 18719196 10.1373/clinchem.2008.109603 1:CAS:528: DC%2BD1cXht1Ciu77F
67. J Wang J Chen P Chang, et al. 2009 MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease Cancer Prev Res (Phila Pa) 2 807 813 10.1158/1940-6207.CAPR-09-0094 1:CAS:528:DC%2BC3cXpt1Sqtbs%3D
68. AS Ho X Huang H Cao, et al. 2010 Circulating miR-210 as a novel hypoxia marker in pancreatic cancer Transl Oncol 3 109 113 20360935
69. N Hanoun Y Delpu AA Suriawinata, et al. 2010 The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis Clin Chem 56 1107 1118 20431052 10.1373/clinchem.2010.144709 1:CAS:528:DC%2BC3cXptVent74%3D