The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis

Clinical Chemistry

Volumn 56, Issue 7, 2010, Pages 1107-1118

  Hanoun, Naïma ^a,b   Delpu, Yannick ^a,b   Suriawinata, Arief A ^c   Bournet, Barbara ^a,d   Bureau, Christophe ^a,b,e   Selves, Janick ^a,b,e   Tsongalis, Gregory J ^c   Dufresne, Marlène ^a,b   Buscail, Louis ^a,b,d   Cordelier, Pierre ^a,b   Torrisani, Jérôme ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c NORRIS COTTON CANCER CENTER   (United States)

^d TOULOUSE UNIVERSITY HOSPITAL   (France)

^e CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; MICRORNA; MICRORNA 148A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CARCINOGENESIS; CHRONIC PANCREATITIS; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DNA METHYLATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PANCREAS ADENOCARCINOMA; PANCREATIC DUCTAL ADENOCARCINOMA; PRECANCER AND CANCER-IN-SITU; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA HYBRIDIZATION;

ANIMALS; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; DIAGNOSIS, DIFFERENTIAL; DNA METHYLATION; DOWN-REGULATION; GENE SILENCING; HUMANS; MICE; MICE, MUTANT STRAINS; MICRORNAS; PANCREATIC NEOPLASMS; PANCREATITIS, CHRONIC; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS;

EID: 77954357983     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.144709     Document Type: Article

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