메뉴 건너뛰기




Volumn 33, Issue 4, 2009, Pages 667-684

MicroRNAs: Control and loss of control in human physiology and disease

Author keywords

[No Author keywords available]

Indexed keywords

LOCKED NUCLEIC ACID; MICRORNA;

EID: 62549098152     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-008-9836-x     Document Type: Review
Times cited : (193)

References (177)
  • 1
    • 42249087308 scopus 로고    scopus 로고
    • The complete genome of an individual by massively parallel DNA sequencing
    • DA Wheeler M Srinivasan M Egholm 2008 The complete genome of an individual by massively parallel DNA sequencing Nature 452 872 876
    • (2008) Nature , vol.452 , pp. 872-876
    • Wheeler, D.A.1    Srinivasan, M.2    Egholm, M.3
  • 2
    • 42249084088 scopus 로고    scopus 로고
    • James Watson's genome sequenced at high speed
    • M Wadman 2008 James Watson's genome sequenced at high speed Nature 452 788
    • (2008) Nature , vol.452 , pp. 788
    • Wadman, M.1
  • 4
    • 43349107172 scopus 로고    scopus 로고
    • Small interfering RNA therapy in cancer: Mechanism, potential targets, and clinical applications
    • C Huang M Li C Chen 2008 Small interfering RNA therapy in cancer: mechanism, potential targets, and clinical applications Expert Opin Ther Targets 12 637 645
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 637-645
    • Huang, C.1    Li, M.2    Chen, C.3
  • 5
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • SM Elbashir J Harborth W Lendeckel 2001 Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 494 498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 6
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • SM Elbashir W Lendeckel T Tuschl 2001 RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev 15 188 200
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 7
    • 36849026128 scopus 로고    scopus 로고
    • Applications of RNA interference in mammalian systems
    • SE Martin NJ Caplen 2007 Applications of RNA interference in mammalian systems Annu Rev Genomics Hum Genet 8 81 108
    • (2007) Annu Rev Genomics Hum Genet , vol.8 , pp. 81-108
    • Martin, S.E.1    Caplen, N.J.2
  • 8
    • 37249011314 scopus 로고    scopus 로고
    • RNAi screening for therapeutic targets in human malignancies
    • DR Micklem JB Lorens 2007 RNAi screening for therapeutic targets in human malignancies Curr Pharm Biotechnol 8 337 343
    • (2007) Curr Pharm Biotechnol , vol.8 , pp. 337-343
    • Micklem, D.R.1    Lorens, J.B.2
  • 9
    • 33644659734 scopus 로고    scopus 로고
    • Mammalian microRNAs: A small world for fine-tuning gene expression
    • C Sevignani GA Calin LD Siracusa 2006 Mammalian microRNAs: a small world for fine-tuning gene expression Mamm Genome 17 189 202
    • (2006) Mamm Genome , vol.17 , pp. 189-202
    • Sevignani, C.1    Calin, G.A.2    Siracusa, L.D.3
  • 10
    • 33750450911 scopus 로고    scopus 로고
    • RNA interference: Mechanisms of action and therapeutic consideration
    • PG Rychahou LN Jackson BJ Farrow 2006 RNA interference: mechanisms of action and therapeutic consideration Surgery 140 719 725
    • (2006) Surgery , vol.140 , pp. 719-725
    • Rychahou, P.G.1    Jackson, L.N.2    Farrow, B.J.3
  • 11
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • L He GJ Hannon 2004 MicroRNAs: small RNAs with a big role in gene regulation Nat Rev Genet 5 522 531
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 12
    • 26944498261 scopus 로고    scopus 로고
    • Approaches for chemically synthesized siRNA and vector-mediated RNAi
    • M Amarzguioui JJ Rossi D Kim 2005 Approaches for chemically synthesized siRNA and vector-mediated RNAi FEBS Lett 579 5974 5981
    • (2005) FEBS Lett , vol.579 , pp. 5974-5981
    • Amarzguioui, M.1    Rossi, J.J.2    Kim, D.3
  • 13
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • W Filipowicz SN Bhattacharyya N Sonenberg 2008 Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9 102 114
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 14
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • A Fire S Xu MK Montgomery 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 806 811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 15
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • RC Lee RL Feinbaum V Ambros 1993 The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 843 854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 16
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • BJ Reinhart FJ Slack M Basson 2000 The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature 403 901 906
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3
  • 19
    • 0037370020 scopus 로고    scopus 로고
    • A uniform system for microRNA annotation
    • V Ambros B Bartel DP Bartel 2003 A uniform system for microRNA annotation RNA 9 277 279
    • (2003) RNA , vol.9 , pp. 277-279
    • Ambros, V.1    Bartel, B.2    Bartel, D.P.3
  • 20
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • BP Lewis CB Burge DP Bartel 2005 Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 15 20
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 21
    • 33749519036 scopus 로고    scopus 로고
    • Implications of micro-RNA profiling for cancer diagnosis
    • JM Cummins VE Velculescu 2006 Implications of micro-RNA profiling for cancer diagnosis Oncogene 25 6220 6227
    • (2006) Oncogene , vol.25 , pp. 6220-6227
    • Cummins, J.M.1    Velculescu, V.E.2
  • 22
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • BP Lewis IH Shih MW Jones-Rhoades 2003 Prediction of mammalian microRNA targets Cell 115 787 798
    • (2003) Cell , vol.115 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3
  • 23
    • 1542297345 scopus 로고    scopus 로고
    • Computational identification of microRNA targets
    • N Rajewsky ND Socci 2004 Computational identification of microRNA targets Dev Biol 267 529 535
    • (2004) Dev Biol , vol.267 , pp. 529-535
    • Rajewsky, N.1    Socci, N.D.2
  • 25
    • 35548996307 scopus 로고    scopus 로고
    • Determinants of targeting by endogenous and exogenous microRNAs and siRNAs
    • CB Nielsen N Shomron R Sandberg 2007 Determinants of targeting by endogenous and exogenous microRNAs and siRNAs RNA 13 1894 1910
    • (2007) RNA , vol.13 , pp. 1894-1910
    • Nielsen, C.B.1    Shomron, N.2    Sandberg, R.3
  • 26
    • 2442672918 scopus 로고    scopus 로고
    • A combined computational-experimental approach predicts human microRNA targets
    • M Kiriakidou PT Nelson A Kouranov 2004 A combined computational- experimental approach predicts human microRNA targets Genes Dev 18 1165 1178
    • (2004) Genes Dev , vol.18 , pp. 1165-1178
    • Kiriakidou, M.1    Nelson, P.T.2    Kouranov, A.3
  • 27
    • 33748587841 scopus 로고    scopus 로고
    • Pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
    • KC Miranda T Huynh Y Tay 2006 Pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes Cell 126 1203 1217
    • (2006) Cell , vol.126 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3
  • 28
    • 31044444975 scopus 로고    scopus 로고
    • TarBase: A comprehensive database of experimentally supported animal microRNA targets
    • P Sethupathy B Corda AG Hatzigeorgiou 2006 TarBase: a comprehensive database of experimentally supported animal microRNA targets RNA 12 192 197
    • (2006) RNA , vol.12 , pp. 192-197
    • Sethupathy, P.1    Corda, B.2    Hatzigeorgiou, A.G.3
  • 29
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
    • A Grimson KK Farh WK Johnston 2007 MicroRNA targeting specificity in mammals: determinants beyond seed pairing Mol Cell 27 91 105
    • (2007) Mol Cell , vol.27 , pp. 91-105
    • Grimson, A.1    Farh, K.K.2    Johnston, W.K.3
  • 30
    • 0037447334 scopus 로고    scopus 로고
    • The microRNAs of Caenorhabditis elegans
    • LP Lim NC Lau EG Weinstein 2003 The microRNAs of Caenorhabditis elegans Genes Dev 17 991 1008
    • (2003) Genes Dev , vol.17 , pp. 991-1008
    • Lim, L.P.1    Lau, N.C.2    Weinstein, E.G.3
  • 31
    • 0036544755 scopus 로고    scopus 로고
    • MicroRNAs are complementary to 3 UTR sequence motifs that mediate negative post-transcriptional regulation
    • EC Lai 2002 MicroRNAs are complementary to 3 UTR sequence motifs that mediate negative post-transcriptional regulation Nat Genet 30 363 364
    • (2002) Nat Genet , vol.30 , pp. 363-364
    • Lai, E.C.1
  • 32
    • 37349050789 scopus 로고    scopus 로고
    • Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer
    • Y Gusev TD Schmittgen M Lerner 2007 Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer BMC Bioinformatics 8 S16
    • (2007) BMC Bioinformatics , vol.8 , pp. 16
    • Gusev, Y.1    Schmittgen, T.D.2    Lerner, M.3
  • 33
    • 33748346026 scopus 로고    scopus 로고
    • Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions
    • D Didiano O Hobert 2006 Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions Nat Struct Mol Biol 13 849 851
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 849-851
    • Didiano, D.1    Hobert, O.2
  • 34
    • 0028196714 scopus 로고
    • From sequences to shapes and back: A case study in RNA secondary structures
    • P Schuster W Fontana PF Stadler 1994 From sequences to shapes and back: a case study in RNA secondary structures Proc Biol Sci 255 279 284
    • (1994) Proc Biol Sci , vol.255 , pp. 279-284
    • Schuster, P.1    Fontana, W.2    Stadler, P.F.3
  • 35
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.org resource: Targets and expression
    • D Betel M Wilson A Gabow 2008 The microRNA.org resource: targets and expression Nucleic Acids Res 36 D149 153
    • (2008) Nucleic Acids Res , vol.36 , pp. 149-153
    • Betel, D.1    Wilson, M.2    Gabow, A.3
  • 36
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • P Landgraf M Rusu R Sheridan 2007 A mammalian microRNA expression atlas based on small RNA library sequencing Cell 129 1401 1414
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 37
    • 39049191809 scopus 로고    scopus 로고
    • Exploration of human miRNA target genes in neuronal differentiation
    • Fukuda Y, Kawasaki H, Taira K (2005) Exploration of human miRNA target genes in neuronal differentiation. Nucleic Acids Symp Ser (Oxf), 341-342
    • (2005) Nucleic Acids Symp ser (Oxf) , pp. 341-342
    • Fukuda, Y.1    Kawasaki, H.2    Taira, K.3
  • 38
    • 0038746673 scopus 로고    scopus 로고
    • Catalytic site-directed gamma-secretase complex inhibitors do not discriminate pharmacologically between Notch S3 and beta-APP cleavages
    • HD Lewis BI Perez Revuelta A Nadin 2003 Catalytic site-directed gamma-secretase complex inhibitors do not discriminate pharmacologically between Notch S3 and beta-APP cleavages Biochemistry 42 7580 7586
    • (2003) Biochemistry , vol.42 , pp. 7580-7586
    • Lewis, H.D.1    Perez Revuelta, B.I.2    Nadin, A.3
  • 39
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • EJ Lee Y Gusev J Jiang 2007 Expression profiling identifies microRNA signature in pancreatic cancer Int J Cancer 120 1046 1054
    • (2007) Int J Cancer , vol.120 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3
  • 40
    • 38049100559 scopus 로고    scopus 로고
    • An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells
    • XB Shi L Xue J Yang 2007 An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells Proc Natl Acad Sci USA 104 19983 19988
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19983-19988
    • Shi, X.B.1    Xue, L.2    Yang, J.3
  • 41
    • 34447117003 scopus 로고    scopus 로고
    • Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
    • L Gramantieri M Ferracin F Fornari 2007 Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma Cancer Res 67 6092 6099
    • (2007) Cancer Res , vol.67 , pp. 6092-6099
    • Gramantieri, L.1    Ferracin, M.2    Fornari, F.3
  • 42
    • 38949168082 scopus 로고    scopus 로고
    • Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines
    • S Mitomo C Maesawa S Ogasawara 2008 Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines Cancer Sci 99 280 286
    • (2008) Cancer Sci , vol.99 , pp. 280-286
    • Mitomo, S.1    Maesawa, C.2    Ogasawara, S.3
  • 43
    • 42349087828 scopus 로고    scopus 로고
    • The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms
    • F Felicetti MC Errico L Bottero 2008 The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms Cancer Res 68 2745 2754
    • (2008) Cancer Res , vol.68 , pp. 2745-2754
    • Felicetti, F.1    Errico, M.C.2    Bottero, L.3
  • 44
    • 34548565806 scopus 로고    scopus 로고
    • Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin
    • GJ Hurteau JA Carlson SD Spivack 2007 Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin Cancer Res 67 7972 7976
    • (2007) Cancer Res , vol.67 , pp. 7972-7976
    • Hurteau, G.J.1    Carlson, J.A.2    Spivack, S.D.3
  • 46
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • H Yang W Kong L He 2008 MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN Cancer Res 68 425 433
    • (2008) Cancer Res , vol.68 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3
  • 47
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • AJ Schetter SY Leung JJ Sohn 2008 MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma JAMA 299 425 436
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1    Leung, S.Y.2    Sohn, J.J.3
  • 48
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • L He JM Thomson MT Hemann 2005 A microRNA polycistron as a potential human oncogene Nature 435 828 833
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 49
    • 14844354250 scopus 로고    scopus 로고
    • Accumulation of miR-155 and BIC RNA in human B cell lymphomas
    • PS Eis W Tam L Sun 2005 Accumulation of miR-155 and BIC RNA in human B cell lymphomas Proc Natl Acad Sci USA 102 3627 3632
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3627-3632
    • Eis, P.S.1    Tam, W.2    Sun, L.3
  • 51
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • J Lu G Getz EA Miska 2005 MicroRNA expression profiles classify human cancers Nature 435 834 838
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 52
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • GA Calin CD Dumitru M Shimizu 2002 Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia Proc Natl Acad Sci USA 99 15524 15529
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 53
    • 33749507943 scopus 로고    scopus 로고
    • A small piece in the cancer puzzle: MicroRNAs as tumor suppressors and oncogenes
    • OA Kent JT Mendell 2006 A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes Oncogene 25 6188 6196
    • (2006) Oncogene , vol.25 , pp. 6188-6196
    • Kent, O.A.1    Mendell, J.T.2
  • 54
    • 25444520537 scopus 로고    scopus 로고
    • MiR-15 and miR-16 induce apoptosis by targeting BCL2
    • A Cimmino GA Calin M Fabbri 2005 miR-15 and miR-16 induce apoptosis by targeting BCL2 Proc Natl Acad Sci USA 102 13944 13949
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 55
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • M Fabbri R Garzon A Cimmino 2007 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B Proc Natl Acad Sci USA 104 15805 15810
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15805-15810
    • Fabbri, M.1    Garzon, R.2    Cimmino, A.3
  • 56
    • 34548012848 scopus 로고    scopus 로고
    • The let-7 microRNA represses cell proliferation pathways in human cells
    • CD Johnson A Esquela-Kerscher G Stefani 2007 The let-7 microRNA represses cell proliferation pathways in human cells Cancer Res 67 7713 7722
    • (2007) Cancer Res , vol.67 , pp. 7713-7722
    • Johnson, C.D.1    Esquela-Kerscher, A.2    Stefani, G.3
  • 57
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • DC Corney A Flesken-Nikitin AK Godwin 2007 MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth Cancer Res 67 8433 8438
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3
  • 58
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • H Tazawa N Tsuchiya M Izumiya 2007 Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells Proc Natl Acad Sci USA 104 15472 15477
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3
  • 59
    • 33646471662 scopus 로고    scopus 로고
    • Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice
    • S Costinean N Zanesi Y Pekarsky 2006 Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice Proc Natl Acad Sci USA 103 7024 7029
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7024-7029
    • Costinean, S.1    Zanesi, N.2    Pekarsky, Y.3
  • 60
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • L Ma J Teruya-Feldstein RA Weinberg 2007 Tumour invasion and metastasis initiated by microRNA-10b in breast cancer Nature 449 682 688
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 61
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • A Ota H Tagawa S Karnan 2004 Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma Cancer Res 64 3087 3095
    • (2004) Cancer Res , vol.64 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3
  • 62
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • JA Chan AM Krichevsky KS Kosik 2005 MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells Cancer Res 65 6029 6033
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 63
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Q Huang K Gumireddy M Schrier 2008 The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis Nat Cell Biol 10 202 210
    • (2008) Nat Cell Biol , vol.10 , pp. 202-210
    • Huang, Q.1    Gumireddy, K.2    Schrier, M.3
  • 64
    • 0027733796 scopus 로고
    • K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
    • RH Hruban AD van Mansfeld GJ Offerhaus 1993 K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization Am J Pathol 143 545 554
    • (1993) Am J Pathol , vol.143 , pp. 545-554
    • Hruban, R.H.1    Van Mansfeld, A.D.2    Offerhaus, G.J.3
  • 65
    • 0036239123 scopus 로고    scopus 로고
    • K-ras, p53, and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: A molecular panel correlates with and supplements cytologic diagnosis
    • T van Heek AE Rader GJ Offerhaus 2002 K-ras, p53, and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: a molecular panel correlates with and supplements cytologic diagnosis Am J Clin Pathol 117 755 765
    • (2002) Am J Clin Pathol , vol.117 , pp. 755-765
    • Van Heek, T.1    Rader, A.E.2    Offerhaus, G.J.3
  • 66
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • CD Logsdon DM Simeone C Binkley 2003 Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer Cancer Res 63 2649 2657
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3
  • 67
    • 31544478790 scopus 로고    scopus 로고
    • Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer
    • L Zhang L Chenwei R Mahmood 2006 Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer Cancer Res 66 898 906
    • (2006) Cancer Res , vol.66 , pp. 898-906
    • Zhang, L.1    Chenwei, L.2    Mahmood, R.3
  • 68
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • AE Szafranska TS Davison J John 2007 MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma Oncogene 26 4442 4452
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3
  • 69
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • C Roldo E Missiaglia JP Hagan 2006 MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior J Clin Oncol 24 4677 4684
    • (2006) J Clin Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3
  • 70
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • M Bloomston WL Frankel F Petrocca 2007 MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis JAMA 297 1901 1908
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3
  • 71
    • 39649117158 scopus 로고    scopus 로고
    • High-dimensional biology to comprehend hepatocellular carcinoma
    • P Vivekanandan OV Singh 2008 High-dimensional biology to comprehend hepatocellular carcinoma Expert Rev Proteomics 5 45 60
    • (2008) Expert Rev Proteomics , vol.5 , pp. 45-60
    • Vivekanandan, P.1    Singh, O.V.2
  • 72
    • 0035910064 scopus 로고    scopus 로고
    • Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver
    • XR Xu J Huang ZG Xu 2001 Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver Proc Natl Acad Sci USA 98 15089 15094
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15089-15094
    • Xu, X.R.1    Huang, J.2    Xu, Z.G.3
  • 73
    • 0038697489 scopus 로고    scopus 로고
    • Differential gene expression in distinct virologic types of hepatocellular carcinoma: Association with liver cirrhosis
    • N Iizuka M Oka H Yamada-Okabe 2003 Differential gene expression in distinct virologic types of hepatocellular carcinoma: association with liver cirrhosis Oncogene 22 3007 3014
    • (2003) Oncogene , vol.22 , pp. 3007-3014
    • Iizuka, N.1    Oka, M.2    Yamada-Okabe, H.3
  • 74
    • 39849108178 scopus 로고    scopus 로고
    • MiR-122, a paradigm for the role of microRNAs in the liver
    • M Girard E Jacquemin A Munnich 2008 miR-122, a paradigm for the role of microRNAs in the liver J Hepatol 48 648 656
    • (2008) J Hepatol , vol.48 , pp. 648-656
    • Girard, M.1    Jacquemin, E.2    Munnich, A.3
  • 75
    • 1842480063 scopus 로고    scopus 로고
    • Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors
    • JR Jacob A Sterczer IA Toshkov 2004 Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors Hepatology 39 1008 1016
    • (2004) Hepatology , vol.39 , pp. 1008-1016
    • Jacob, J.R.1    Sterczer, A.2    Toshkov, I.A.3
  • 76
    • 0037151790 scopus 로고    scopus 로고
    • Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein
    • H Harada H Nagai Y Ezura 2002 Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein Gene 296 171 177
    • (2002) Gene , vol.296 , pp. 171-177
    • Harada, H.1    Nagai, H.2    Ezura, Y.3
  • 77
    • 48549091046 scopus 로고    scopus 로고
    • Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis
    • J Datta H Kutay MW Nasser 2008 Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis Cancer Res 68 5049 5058
    • (2008) Cancer Res , vol.68 , pp. 5049-5058
    • Datta, J.1    Kutay, H.2    Nasser, M.W.3
  • 78
    • 46249125127 scopus 로고    scopus 로고
    • MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1
    • QW Wong RW Lung PT Law 2008 MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1 Gastroenterology 135 257 269
    • (2008) Gastroenterology , vol.135 , pp. 257-269
    • Wong, Q.W.1    Lung, R.W.2    Law, P.T.3
  • 79
    • 34247495591 scopus 로고    scopus 로고
    • MiR-21-mediated tumor growth
    • ML Si S Zhu H Wu 2007 miR-21-mediated tumor growth Oncogene 26 2799 2803
    • (2007) Oncogene , vol.26 , pp. 2799-2803
    • Si, M.L.1    Zhu, S.2    Wu, H.3
  • 80
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • F Meng R Henson M Lang 2006 Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines Gastroenterology 130 2113 2129
    • (2006) Gastroenterology , vol.130 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3
  • 81
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • S Zhu ML Si H Wu 2007 MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1) J Biol Chem 282 14328 14336
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3
  • 82
    • 0142120587 scopus 로고    scopus 로고
    • Reduced accumulation of specific microRNAs in colorectal neoplasia
    • MZ Michael OC SM NG van Holst Pellekaan 2003 Reduced accumulation of specific microRNAs in colorectal neoplasia Mol Cancer Res 1 882 891
    • (2003) Mol Cancer Res , vol.1 , pp. 882-891
    • Michael, M.Z.1    Sm, O.C.2    Van Holst Pellekaan, N.G.3
  • 84
    • 34249047317 scopus 로고    scopus 로고
    • MicroRNA-143 and -145 in colon cancer
    • Y Akao Y Nakagawa T Naoe 2007 MicroRNA-143 and -145 in colon cancer DNA Cell Biol 26 311 320
    • (2007) DNA Cell Biol , vol.26 , pp. 311-320
    • Akao, Y.1    Nakagawa, Y.2    Naoe, T.3
  • 85
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • M Toyota H Suzuki Y Sasaki 2008 Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer Cancer Res 68 4123 4132
    • (2008) Cancer Res , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3
  • 86
    • 44449125989 scopus 로고    scopus 로고
    • Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer
    • WM Grady RK Parkin PS Mitchell 2008 Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer Oncogene 27 3880 3888
    • (2008) Oncogene , vol.27 , pp. 3880-3888
    • Grady, W.M.1    Parkin, R.K.2    Mitchell, P.S.3
  • 87
    • 15744391012 scopus 로고    scopus 로고
    • Dicer is required for embryonic angiogenesis during mouse development
    • WJ Yang DD Yang S Na 2005 Dicer is required for embryonic angiogenesis during mouse development J Biol Chem 280 9330 9335
    • (2005) J Biol Chem , vol.280 , pp. 9330-9335
    • Yang, W.J.1    Yang, D.D.2    Na, S.3
  • 88
    • 40749106180 scopus 로고    scopus 로고
    • Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells
    • S Shilo S Roy S Khanna 2008 Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells Arterioscler Thromb Vasc Biol 28 471 477
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 471-477
    • Shilo, S.1    Roy, S.2    Khanna, S.3
  • 89
    • 34447632218 scopus 로고    scopus 로고
    • Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis
    • A Kuehbacher C Urbich AM Zeiher 2007 Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis Circ Res 101 59 68
    • (2007) Circ Res , vol.101 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3
  • 90
    • 33751173635 scopus 로고    scopus 로고
    • MicroRNAs modulate the angiogenic properties of HUVECs
    • L Poliseno A Tuccoli L Mariani 2006 MicroRNAs modulate the angiogenic properties of HUVECs Blood 108 3068 3071
    • (2006) Blood , vol.108 , pp. 3068-3071
    • Poliseno, L.1    Tuccoli, A.2    Mariani, L.3
  • 91
    • 34548207751 scopus 로고    scopus 로고
    • The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microrna-155 binding
    • MM Martin JA Buckenberger J Jiang 2007 The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microrna-155 binding J Biol Chem 282 24262 24269
    • (2007) J Biol Chem , vol.282 , pp. 24262-24269
    • Martin, M.M.1    Buckenberger, J.A.2    Jiang, J.3
  • 92
    • 0032693599 scopus 로고    scopus 로고
    • Atherosclerosis is an inflammatory disease
    • R Ross 1999 Atherosclerosis is an inflammatory disease Am Heart J 138 S419 420
    • (1999) Am Heart J , vol.138 , pp. 419-420
    • Ross, R.1
  • 93
    • 40349103409 scopus 로고    scopus 로고
    • MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    • TA Harris M Yamakuchi M Ferlito 2008 MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1 Proc Natl Acad Sci USA 105 1516 1521
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1516-1521
    • Harris, T.A.1    Yamakuchi, M.2    Ferlito, M.3
  • 94
    • 33846845071 scopus 로고    scopus 로고
    • MicroRNA-155 is induced during the macrophage inflammatory response
    • RM O'Connell KD Taganov MP Boldin 2007 MicroRNA-155 is induced during the macrophage inflammatory response Proc Natl Acad Sci USA 104 1604 1609
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1604-1609
    • O'Connell, R.M.1    Taganov, K.D.2    Boldin, M.P.3
  • 95
    • 33645075443 scopus 로고    scopus 로고
    • MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
    • C Esau S Davis SF Murray 2006 miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting Cell Metab 3 87 98
    • (2006) Cell Metab , vol.3 , pp. 87-98
    • Esau, C.1    Davis, S.2    Murray, S.F.3
  • 96
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • R Ji Y Cheng J Yue 2007 MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation Circ Res 100 1579 1588
    • (2007) Circ Res , vol.100 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3
  • 97
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • A Krek D Grun MN Poy 2005 Combinatorial microRNA target predictions Nat Genet 37 495 500
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 98
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • CZ Chen L Li HF Lodish 2004 MicroRNAs modulate hematopoietic lineage differentiation Science 303 83 86
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3
  • 99
    • 24644489402 scopus 로고    scopus 로고
    • MicroRNA profiling of the murine hematopoietic system
    • S Monticelli KM Ansel C Xiao 2005 MicroRNA profiling of the murine hematopoietic system Genome Biol 6 R71
    • (2005) Genome Biol , vol.6 , pp. 71
    • Monticelli, S.1    Ansel, K.M.2    Xiao, C.3
  • 100
    • 38349016948 scopus 로고    scopus 로고
    • MiRNA profiling of naive, effector and memory CD8 T cells
    • H Wu JR Neilson P Kumar 2007 miRNA profiling of naive, effector and memory CD8 T cells PLoS ONE 2 e1020
    • (2007) PLoS ONE , vol.2 , pp. 1020
    • Wu, H.1    Neilson, J.R.2    Kumar, P.3
  • 102
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • SM Kaech S Hemby E Kersh 2002 Molecular and functional profiling of memory CD8 T cell differentiation Cell 111 837 851
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3
  • 103
    • 33947104955 scopus 로고    scopus 로고
    • Dynamic regulation of miRNA expression in ordered stages of cellular development
    • JR Neilson GX Zheng CB Burge 2007 Dynamic regulation of miRNA expression in ordered stages of cellular development Genes Dev 21 578 589
    • (2007) Genes Dev , vol.21 , pp. 578-589
    • Neilson, J.R.1    Zheng, G.X.2    Burge, C.B.3
  • 104
    • 22944433872 scopus 로고    scopus 로고
    • Aberrant T cell differentiation in the absence of Dicer
    • SA Muljo KM Ansel C Kanellopoulou 2005 Aberrant T cell differentiation in the absence of Dicer J Ext Med 202 261 269
    • (2005) J Ext Med , vol.202 , pp. 261-269
    • Muljo, S.A.1    Ansel, K.M.2    Kanellopoulou, C.3
  • 105
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • KD Taganov MP Boldin KJ Chang 2006 NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses Proc Natl Acad Sci USA 103 12481 12486
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3
  • 106
    • 33644866985 scopus 로고    scopus 로고
    • Hematopoietic-specific microRNA expression in human cells
    • SH Ramkissoon LA Mainwaring Y Ogasawara 2006 Hematopoietic-specific microRNA expression in human cells Leuk Res 30 643 647
    • (2006) Leuk Res , vol.30 , pp. 643-647
    • Ramkissoon, S.H.1    Mainwaring, L.A.2    Ogasawara, Y.3
  • 107
    • 39749101294 scopus 로고    scopus 로고
    • Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
    • SB Koralov SA Muljo GR Galler 2008 Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage Cell 132 860 874
    • (2008) Cell , vol.132 , pp. 860-874
    • Koralov, S.B.1    Muljo, S.A.2    Galler, G.R.3
  • 108
    • 22544440566 scopus 로고    scopus 로고
    • MicroRNA-binding viral protein interferes with Arabidopsis development
    • P Chellappan R Vanitharani CM Fauquet 2005 MicroRNA-binding viral protein interferes with Arabidopsis development Proc Natl Acad Sci USA 102 10381 10386
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10381-10386
    • Chellappan, P.1    Vanitharani, R.2    Fauquet, C.M.3
  • 109
    • 34249699555 scopus 로고    scopus 로고
    • Rapid transit in the immune cells: The role of mRNA turnover regulation
    • KS Khabar 2007 Rapid transit in the immune cells: the role of mRNA turnover regulation J Leuk Biol 81 1335 1344
    • (2007) J Leuk Biol , vol.81 , pp. 1335-1344
    • Khabar, K.S.1
  • 110
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Q Jing S Huang S Guth 2005 Involvement of microRNA in AU-rich element-mediated mRNA instability Cell 120 623 634
    • (2005) Cell , vol.120 , pp. 623-634
    • Jing, Q.1    Huang, S.2    Guth, S.3
  • 111
    • 33750499991 scopus 로고    scopus 로고
    • A role for Dicer in immune regulation
    • BS Cobb A Hertweck J Smith 2006 A role for Dicer in immune regulation J Exp Med 203 2519 2527
    • (2006) J Exp Med , vol.203 , pp. 2519-2527
    • Cobb, B.S.1    Hertweck, A.2    Smith, J.3
  • 112
    • 45249117694 scopus 로고    scopus 로고
    • Regulation of B- and T-cell differentiation by a single microRNA
    • M Turner E Vigorito 2008 Regulation of B- and T-cell differentiation by a single microRNA Biochem Soc Trans 36 531 533
    • (2008) Biochem Soc Trans , vol.36 , pp. 531-533
    • Turner, M.1    Vigorito, E.2
  • 113
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • E Tili JJ Michaille A Cimino 2007 Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock J Immunol 179 5082 5089
    • (2007) J Immunol , vol.179 , pp. 5082-5089
    • Tili, E.1    Michaille, J.J.2    Cimino, A.3
  • 114
    • 45549101837 scopus 로고    scopus 로고
    • Rapid changes in microRNA-146a expression negatively regulate the IL-1beta-induced inflammatory response in human lung alveolar epithelial cells
    • MM Perry SA Moschos AE Williams 2008 Rapid changes in microRNA-146a expression negatively regulate the IL-1beta-induced inflammatory response in human lung alveolar epithelial cells J Immunol 180 5689 5698
    • (2008) J Immunol , vol.180 , pp. 5689-5698
    • Perry, M.M.1    Moschos, S.A.2    Williams, A.E.3
  • 115
    • 33947721625 scopus 로고    scopus 로고
    • MiR-181a is an intrinsic modulator of T cell sensitivity and selection
    • QJ Li J Chau PJ Ebert 2007 miR-181a is an intrinsic modulator of T cell sensitivity and selection Cell 129 147 161
    • (2007) Cell , vol.129 , pp. 147-161
    • Li, Q.J.1    Chau, J.2    Ebert, P.J.3
  • 116
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
    • F Fazi A Rosa A Fatica 2005 A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis Cell 123 819 831
    • (2005) Cell , vol.123 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3
  • 117
    • 34247483919 scopus 로고    scopus 로고
    • An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
    • T Fukao Y Fukuda K Kiga 2007 An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling Cell 129 617 631
    • (2007) Cell , vol.129 , pp. 617-631
    • Fukao, T.1    Fukuda, Y.2    Kiga, K.3
  • 118
    • 34547774686 scopus 로고    scopus 로고
    • Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids
    • SA Moschos AE Williams MM Perry 2007 Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids BMC genomics 8 240
    • (2007) BMC Genomics , vol.8 , pp. 240
    • Moschos, S.A.1    Williams, A.E.2    Perry, M.M.3
  • 119
    • 39749163245 scopus 로고    scopus 로고
    • Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
    • C Xiao L Srinivasan DP Calado 2008 Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes Nat Immunol 9 405 414
    • (2008) Nat Immunol , vol.9 , pp. 405-414
    • Xiao, C.1    Srinivasan, L.2    Calado, D.P.3
  • 120
    • 34147120549 scopus 로고    scopus 로고
    • A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity
    • X Mao BE Kim F Wang 2007 A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity J Biol Chem 282 6992 7000
    • (2007) J Biol Chem , vol.282 , pp. 6992-7000
    • Mao, X.1    Kim, B.E.2    Wang, F.3
  • 121
    • 0037402495 scopus 로고    scopus 로고
    • High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma
    • A van den Berg BJ Kroesen K Kooistra 2003 High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma Genes Chromosomes Cancer 37 20 28
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 20-28
    • Van Den Berg, A.1    Kroesen, B.J.2    Kooistra, K.3
  • 122
    • 0036229658 scopus 로고    scopus 로고
    • Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis
    • W Tam SH Hughes WS Hayward 2002 Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis J Virol 76 4275 4286
    • (2002) J Virol , vol.76 , pp. 4275-4286
    • Tam, W.1    Hughes, S.H.2    Hayward, W.S.3
  • 123
    • 41149130219 scopus 로고    scopus 로고
    • Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
    • RM O'Connell DS Rao AA Chaudhuri 2008 Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder J Exp Med 205 585 594
    • (2008) J Exp Med , vol.205 , pp. 585-594
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3
  • 124
    • 0346727383 scopus 로고    scopus 로고
    • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
    • M Metzler M Wilda K Busch 2004 High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma Genes Chromosomes Cancer 39 167 169
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 167-169
    • Metzler, M.1    Wilda, M.2    Busch, K.3
  • 125
    • 34247594818 scopus 로고    scopus 로고
    • Regulation of the germinal center response by microRNA-155
    • TH Thai DP Calado S Casola 2007 Regulation of the germinal center response by microRNA-155 Science 316 604 608
    • (2007) Science , vol.316 , pp. 604-608
    • Thai, T.H.1    Calado, D.P.2    Casola, S.3
  • 126
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • A Rodriguez E Vigorito S Clare 2007 Requirement of bic/microRNA-155 for normal immune function Science 316 608 611
    • (2007) Science , vol.316 , pp. 608-611
    • Rodriguez, A.1    Vigorito, E.2    Clare, S.3
  • 127
    • 37549015263 scopus 로고    scopus 로고
    • Germinal centers: Role in B-cell physiology and malignancy
    • U Klein R Dalla-Favera 2008 Germinal centers: role in B-cell physiology and malignancy Nat Rev 8 22 33
    • (2008) Nat Rev , vol.8 , pp. 22-33
    • Klein, U.1    Dalla-Favera, R.2
  • 128
    • 0036792086 scopus 로고    scopus 로고
    • An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines
    • ES Hwang IA White IC Ho 2002 An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines Proc Natl Acad Sci USA 99 13026 13030
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13026-13030
    • Hwang, E.S.1    White, I.A.2    Ho, I.C.3
  • 129
    • 37049017580 scopus 로고    scopus 로고
    • MicroRNA-155 function in B Cells
    • K Calame 2007 MicroRNA-155 function in B Cells Immunity 27 825 827
    • (2007) Immunity , vol.27 , pp. 825-827
    • Calame, K.1
  • 130
    • 37049002638 scopus 로고    scopus 로고
    • MicroRNA-155 regulates the generation of immunoglobulin class-switched plasma cells
    • E Vigorito KL Perks C Abreu-Goodger 2007 microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells Immunity 27 847 859
    • (2007) Immunity , vol.27 , pp. 847-859
    • Vigorito, E.1    Perks, K.L.2    Abreu-Goodger, C.3
  • 131
    • 29544440920 scopus 로고    scopus 로고
    • A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity
    • MN Blumenthal CD Langefeld KC Barnes 2006 A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity J Allergy Clin Immunol 117 79 85
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 79-85
    • Blumenthal, M.N.1    Langefeld, C.D.2    Barnes, K.C.3
  • 132
    • 33745260396 scopus 로고    scopus 로고
    • Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population
    • LM Bu M Bradley C Soderhall 2006 Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population Allergy 61 617 621
    • (2006) Allergy , vol.61 , pp. 617-621
    • Bu, L.M.1    Bradley, M.2    Soderhall, C.3
  • 133
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • JE Parrillo 1993 Pathogenetic mechanisms of septic shock Engl J Med 328 1471 1477
    • (1993) Engl J Med , vol.328 , pp. 1471-1477
    • Parrillo, J.E.1
  • 135
    • 22344437262 scopus 로고    scopus 로고
    • Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
    • Y Ueda M Kondo G Kelsoe 2005 Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow J Exp Med 201 1771 1780
    • (2005) J Exp Med , vol.201 , pp. 1771-1780
    • Ueda, Y.1    Kondo, M.2    Kelsoe, G.3
  • 136
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • I Bentwich A Avniel Y Karov 2005 Identification of hundreds of conserved and nonconserved human microRNAs Nat Genet 37 766 770
    • (2005) Nat Genet , vol.37 , pp. 766-770
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 137
    • 42449119265 scopus 로고    scopus 로고
    • "fine tuning" TLR signaling
    • LA O'Neill 2008 "Fine tuning" TLR signaling Nat Immunol 9 459 461
    • (2008) Nat Immunol , vol.9 , pp. 459-461
    • O'Neill, L.A.1
  • 138
    • 43549120764 scopus 로고    scopus 로고
    • TRAF-mediated TNFR-family signaling
    • Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (eds) chapter 11, Unit 11, 19D
    • Arron JR, Walsh MC, Choi Y (2002) TRAF-mediated TNFR-family signaling. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (eds) Current protocols in immunology, chapter 11, Unit 11, 19D
    • (2002) Current Protocols in Immunology
    • Arron, J.R.1    Walsh, M.C.2    Choi, Y.3
  • 139
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • MA Lowes AM Bowcock JG Krueger 2007 Pathogenesis and therapy of psoriasis Nature 445 866 873
    • (2007) Nature , vol.445 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 140
    • 77951233965 scopus 로고    scopus 로고
    • MicroRNAs: Novel regulators involved in the pathogenesis of Psoriasis?
    • E Sonkoly T Wei PC Janson 2007 MicroRNAs: novel regulators involved in the pathogenesis of Psoriasis? PLoS ONE 2 e610
    • (2007) PLoS ONE , vol.2 , pp. 610
    • Sonkoly, E.1    Wei, T.2    Janson, P.C.3
  • 141
    • 43949136123 scopus 로고    scopus 로고
    • Expression of microRNA-146 in rheumatoid arthritis synovial tissue
    • T Nakasa S Miyaki A Okubo 2008 Expression of microRNA-146 in rheumatoid arthritis synovial tissue Arthritis Rheum 58 1284 1292
    • (2008) Arthritis Rheum , vol.58 , pp. 1284-1292
    • Nakasa, T.1    Miyaki, S.2    Okubo, A.3
  • 142
    • 34547941361 scopus 로고    scopus 로고
    • MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb
    • C Xiao DP Calado G Galler 2007 MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb Cell 131 146 159
    • (2007) Cell , vol.131 , pp. 146-159
    • Xiao, C.1    Calado, D.P.2    Galler, G.3
  • 143
    • 44449100618 scopus 로고    scopus 로고
    • Hematopoietic lineage commitment: MiRNAs add specificity to a widely expressed transcription factor
    • P Garcia J Frampton 2008 Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor Developmental cell 14 815 816
    • (2008) Developmental Cell , vol.14 , pp. 815-816
    • Garcia, P.1    Frampton, J.2
  • 144
    • 34249851499 scopus 로고    scopus 로고
    • MiR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely
    • B Zhou S Wang C Mayr 2007 miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely Proc Natl Acad Sci USA 104 7080 7085
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7080-7085
    • Zhou, B.1    Wang, S.2    Mayr, C.3
  • 145
    • 50649089178 scopus 로고    scopus 로고
    • Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer
    • BB Williams M Wall RY Miao 2008 Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer Cancer Immunol Immunother 57 1635 1645
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1635-1645
    • Williams, B.B.1    Wall, M.2    Miao, R.Y.3
  • 146
    • 44449108570 scopus 로고    scopus 로고
    • MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors
    • J Lu S Guo BL Ebert 2008 MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors Dev Cell 14 843 853
    • (2008) Dev Cell , vol.14 , pp. 843-853
    • Lu, J.1    Guo, S.2    Ebert, B.L.3
  • 147
    • 0028179068 scopus 로고
    • The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice
    • H Karasuyama A Rolink Y Shinkai 1994 The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice Cell 77 133 143
    • (1994) Cell , vol.77 , pp. 133-143
    • Karasuyama, H.1    Rolink, A.2    Shinkai, Y.3
  • 148
    • 33846190181 scopus 로고    scopus 로고
    • Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
    • Y Pekarsky U Santanam A Cimmino 2006 Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181 Cancer Res 66 11590 11593
    • (2006) Cancer Res , vol.66 , pp. 11590-11593
    • Pekarsky, Y.1    Santanam, U.2    Cimmino, A.3
  • 149
    • 45549097192 scopus 로고    scopus 로고
    • Innate recognition of non-self nucleic acids
    • H Chi RA Flavell 2008 Innate recognition of non-self nucleic acids Genome Biol 9 211
    • (2008) Genome Biol , vol.9 , pp. 211
    • Chi, H.1    Flavell, R.A.2
  • 150
    • 42449152333 scopus 로고    scopus 로고
    • MiR-15a and miR-16-1 cluster functions in human leukemia
    • GA Calin A Cimmino M Fabbri 2008 MiR-15a and miR-16-1 cluster functions in human leukemia Proc Natl Acad Sci USA 105 5166 5171
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5166-5171
    • Calin, G.A.1    Cimmino, A.2    Fabbri, M.3
  • 151
    • 39849096995 scopus 로고    scopus 로고
    • Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    • JB Johnnidis MH Harris RT Wheeler 2008 Regulation of progenitor cell proliferation and granulocyte function by microRNA-223 Nature 451 1125 1129
    • (2008) Nature , vol.451 , pp. 1125-1129
    • Johnnidis, J.B.1    Harris, M.H.2    Wheeler, R.T.3
  • 152
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
    • A Ventura AG Young MM Winslow 2008 Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters Cell 132 875 886
    • (2008) Cell , vol.132 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3
  • 153
    • 33947224690 scopus 로고    scopus 로고
    • Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
    • PS Linsley J Schelter J Burchard 2007 Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression Mol Cell Biol 27 2240 2252
    • (2007) Mol Cell Biol , vol.27 , pp. 2240-2252
    • Linsley, P.S.1    Schelter, J.2    Burchard, J.3
  • 154
    • 38949171376 scopus 로고    scopus 로고
    • MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components
    • AJ Asirvatham CJ Gregorie Z Hu 2008 MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components Mol Immunol 45 1995 2006
    • (2008) Mol Immunol , vol.45 , pp. 1995-2006
    • Asirvatham, A.J.1    Gregorie, C.J.2    Hu, Z.3
  • 155
    • 34547542489 scopus 로고    scopus 로고
    • Infection and coaccumulation of tobacco mosaic virus proteins alter microRNA levels, correlating with symptom and plant development
    • AA Bazzini HE Hopp RN Beachy 2007 Infection and coaccumulation of tobacco mosaic virus proteins alter microRNA levels, correlating with symptom and plant development Proc Natl Acad Sci USA 104 12157 12162
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12157-12162
    • Bazzini, A.A.1    Hopp, H.E.2    Beachy, R.N.3
  • 156
    • 17644363376 scopus 로고    scopus 로고
    • A cellular microRNA mediates antiviral defense in human cells
    • CH Lecellier P Dunoyer K Arar 2005 A cellular microRNA mediates antiviral defense in human cells Science 308 557 560
    • (2005) Science , vol.308 , pp. 557-560
    • Lecellier, C.H.1    Dunoyer, P.2    Arar, K.3
  • 157
    • 36048994739 scopus 로고    scopus 로고
    • Analysis of the interaction of primate retroviruses with the human RNA interference machinery
    • J Lin BR Cullen 2007 Analysis of the interaction of primate retroviruses with the human RNA interference machinery J Virol 81 12218 12226
    • (2007) J Virol , vol.81 , pp. 12218-12226
    • Lin, J.1    Cullen, B.R.2
  • 158
    • 35349009932 scopus 로고    scopus 로고
    • Interferon modulation of cellular microRNAs as an antiviral mechanism
    • IM Pedersen G Cheng S Wieland 2007 Interferon modulation of cellular microRNAs as an antiviral mechanism Nature 449 919 922
    • (2007) Nature , vol.449 , pp. 919-922
    • Pedersen, I.M.1    Cheng, G.2    Wieland, S.3
  • 159
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • CL Jopling M Yi AM Lancaster 2005 Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA Science 309 1577 1581
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3
  • 160
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • GK Scott MD Mattie CE Berger 2006 Rapid alteration of microRNA levels by histone deacetylase inhibition Cancer Res 66 1277 1281
    • (2006) Cancer Res , vol.66 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3
  • 161
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Y Saito G Liang G Egger 2006 Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells Cancer Cell 9 435 443
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3
  • 162
    • 33749598345 scopus 로고    scopus 로고
    • Epigenetic activation of tumor suppressor microRNAs in human cancer cells
    • Y Saito PA Jones 2006 Epigenetic activation of tumor suppressor microRNAs in human cancer cells Cell Cycle 5 2220 2222
    • (2006) Cell Cycle , vol.5 , pp. 2220-2222
    • Saito, Y.1    Jones, P.A.2
  • 163
    • 33749633636 scopus 로고    scopus 로고
    • MicroRNAs: A new insight into cancer genome
    • L Zhang G Coukos 2006 MicroRNAs: a new insight into cancer genome Cell Cycle 5 2216 2219
    • (2006) Cell Cycle , vol.5 , pp. 2216-2219
    • Zhang, L.1    Coukos, G.2
  • 164
    • 33745168962 scopus 로고    scopus 로고
    • MicroRNAs exhibit high frequency genomic alterations in human cancer
    • L Zhang J Huang N Yang 2006 microRNAs exhibit high frequency genomic alterations in human cancer Proc Natl Acad Sci USA 103 9136 9141
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9136-9141
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 165
    • 27244434788 scopus 로고    scopus 로고
    • A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • GA Calin M Ferracin A Cimmino 2005 A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia N Engl J Med 353 1793 1801
    • (2005) N Engl J Med , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 166
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • J Takamizawa H Konishi K Yanagisawa 2004 Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival Cancer Res 64 3753 3756
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 167
    • 33845624889 scopus 로고    scopus 로고
    • MicroRNAs in biological processes and carcinogenesis
    • H Osada T Takahashi 2007 MicroRNAs in biological processes and carcinogenesis Carcinogenesis 28 2 12
    • (2007) Carcinogenesis , vol.28 , pp. 2-12
    • Osada, H.1    Takahashi, T.2
  • 168
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • YS Lee HK Kim S Chung 2005 Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation J Biol Chem 280 16635 16641
    • (2005) J Biol Chem , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3
  • 169
    • 34248634004 scopus 로고    scopus 로고
    • Therapeutic potential for microRNAs
    • CC Esau BP Monia 2007 Therapeutic potential for microRNAs Adv Drug Deliv Rev 59 101 114
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 101-114
    • Esau, C.C.1    Monia, B.P.2
  • 170
    • 33846083393 scopus 로고    scopus 로고
    • Regulation of microRNA by antagomirs: A new class of pharmacological antagonists for the specific regulation of gene function?
    • J Mattes M Yang PS Foster 2007 Regulation of microRNA by antagomirs: a new class of pharmacological antagonists for the specific regulation of gene function? Am J Respir Cell Mol Biol 36 8 12
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 8-12
    • Mattes, J.1    Yang, M.2    Foster, P.S.3
  • 171
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • J Krutzfeldt N Rajewsky R Braich 2005 Silencing of microRNAs in vivo with 'antagomirs' Nature 438 685 689
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 172
    • 34250679056 scopus 로고    scopus 로고
    • Locked nucleic acid oligonucleotides: The next generation of antisense agents?
    • A Grunweller RK Hartmann 2007 Locked nucleic acid oligonucleotides: the next generation of antisense agents? BioDrugs 21 235 243
    • (2007) BioDrugs , vol.21 , pp. 235-243
    • Grunweller, A.1    Hartmann, R.K.2
  • 173
    • 33646027887 scopus 로고    scopus 로고
    • LNA-modified oligonucleotides mediate specific inhibition of microRNA function
    • UA Orom S Kauppinen AH Lund 2006 LNA-modified oligonucleotides mediate specific inhibition of microRNA function Gene 372 137 141
    • (2006) Gene , vol.372 , pp. 137-141
    • Orom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 174
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • MS Ebert JR Neilson PA Sharp 2007 MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells Nat Methods 4 721 726
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 175
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • CB Yoo PA Jones 2006 Epigenetic therapy of cancer: past, present and future Nat Rev Drug Discov 5 37 50
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 176
    • 19344378192 scopus 로고    scopus 로고
    • Sequence-specific inhibition of small RNA function
    • G Hutvagner MJ Simard CC Mello 2004 Sequence-specific inhibition of small RNA function PLoS Biol 2 E98
    • (2004) PLoS Biol , vol.2 , pp. 98
    • Hutvagner, G.1    Simard, M.J.2    Mello, C.C.3
  • 177
    • 20444436381 scopus 로고    scopus 로고
    • Cancer genomics: Small RNAs with big impacts
    • PS Meltzer 2005 Cancer genomics: small RNAs with big impacts Nature 435 745 746
    • (2005) Nature , vol.435 , pp. 745-746
    • Meltzer, P.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.