Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase

Cellular Signalling

Volumn 23, Issue 11, 2011, Pages 1824-1830

  Su, Chih Hao ^b   Wang, Cheng Yi ^b   Lan, Keng Hsin ^a   Li, Chung Pin ^a   Chao, Yee ^a   Lin, Han Chieh ^a   Lee, Shou Dong ^a   Lee, Wei Ping ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Akt; CHIP; Hsp90; Proteasome

Indexed keywords

C TERMINAL HSP70 INTERACTING PROTEIN; HEAT SHOCK PROTEIN 90; PROTEIN KINASE B; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UBIQUITINATION;

ANIMALS; CARRIER PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MICE; MUTATION; PHOSPHORYLATION; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; SERINE; SIGNAL TRANSDUCTION; THREONINE; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MAMMALIA;

EID: 80051469504     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.06.018     Document Type: Article

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