Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4869-4872

  Ammazzalorso, Alessandra ^a   Giancristofaro, Antonella ^b   D'Angelo, Alessandra ^a   De Filippis, Barbara ^a   Fantacuzzi, Marialuigia ^a   Giampietro, Letizia ^a   MacCallini, Cristina ^a   Amoroso, Rosa ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b Consorzio Mario Negri Sud ^*  (Italy)

Author keywords

Benzothiazole scaffold; N (phenylsulfonyl)amides; Nuclear receptors; PPAR antagonists

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; BENZOTHIAZOLE DERIVATIVE; CARNITINE PALMITOYLTRANSFERASE I; N (PHENYLSULFONYL)AMIDE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; KIDNEY CELL; PROTEIN EXPRESSION;

EID: 79960898988     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.028     Document Type: Article

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