메뉴 건너뛰기




Volumn 1229, Issue 1, 2011, Pages 124-132

Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis

Author keywords

Chemoprevention; Myricetin; Signaling pathway; Skin carcinogenesis

Indexed keywords

CYCLOOXYGENASE 2; JANUS KINASE; MYRICETIN; PROTEIN KINASE B; PROTEIN KINASE FYN; RAF PROTEIN; STAT3 PROTEIN;

EID: 79960813353     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.06122.x     Document Type: Article
Times cited : (68)

References (73)
  • 1
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
    • Hertog, M.G. et al 1993. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 342: 1007-1011.
    • (1993) Lancet , vol.342 , pp. 1007-1011
    • Hertog, M.G.1
  • 2
    • 0017787237 scopus 로고
    • Flavonoid glycosides and hydroxycinnamic acid esters of blackcurrants (Ribes nigrum)
    • Koeppen, B.H. & K. Herrmann 1977. Flavonoid glycosides and hydroxycinnamic acid esters of blackcurrants (Ribes nigrum). Phenolics of fruits 9. Z Lebensm Unters Forsch. 164: 263-268.
    • (1977) Phenolics of fruits 9. Z Lebensm Unters Forsch. , vol.164 , pp. 263-268
    • Koeppen, B.H.1    Herrmann, K.2
  • 3
    • 33750432828 scopus 로고    scopus 로고
    • Metabolite profiling of grape: flavonols and anthocyanins
    • Mattivi, F. et al 2006. Metabolite profiling of grape: flavonols and anthocyanins. J. Agric. Food Chem. 54: 7692-7702.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 7692-7702
    • Mattivi, F.1
  • 4
    • 0027291905 scopus 로고
    • Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
    • Hertog, M.G. et al 1993. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr. Cancer 20: 21-29.
    • (1993) Nutr. Cancer , vol.20 , pp. 21-29
    • Hertog, M.G.1
  • 5
    • 0015422463 scopus 로고
    • Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro
    • Griffiths, L.A. & G.E. Smith 1972. Metabolism of myricetin and related compounds in the rat. Metabolite formation in vivo and by the intestinal microflora in vitro. Biochem. J. 130: 141-151.
    • (1972) Biochem. J. , vol.130 , pp. 141-151
    • Griffiths, L.A.1    Smith, G.E.2
  • 6
    • 0029610477 scopus 로고
    • Review of the biology of Quercetin and related bioflavonoids
    • Formica, J.V. & W. Regelson 1995. Review of the biology of Quercetin and related bioflavonoids. Food Chem. Toxicol. 33: 1061-1080.
    • (1995) Food Chem. Toxicol. , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 7
    • 20244375365 scopus 로고    scopus 로고
    • UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin
    • Luo, J.L. et al 2001. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin. Cancer Res. 61: 8158-8163.
    • (2001) Cancer Res. , vol.61 , pp. 8158-8163
    • Luo, J.L.1
  • 8
    • 0023689015 scopus 로고
    • Incidence of cutaneous melanoma in the United States by histology with special reference to the face
    • Newell, G.R. et al 1988. Incidence of cutaneous melanoma in the United States by histology with special reference to the face. Cancer Res. 48: 5036-5041.
    • (1988) Cancer Res. , vol.48 , pp. 5036-5041
    • Newell, G.R.1
  • 9
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV-induced signal transduction
    • Bode, A.M. & Z. Dong 2003. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci. STKE 167: 1-15.
    • (2003) Sci. STKE , vol.167 , pp. 1-15
    • Bode, A.M.1    Dong, Z.2
  • 10
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • Thomas, S.M. & J.S. Brugge 1997. Cellular functions regulated by Src family kinases. Annu. Rev. Cell Dev. Biol. 13: 513-609.
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 11
    • 0036186833 scopus 로고    scopus 로고
    • Overexpression of a constitutively active form of c-Src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
    • Matsumoto, T. et al 2002. Overexpression of a constitutively active form of c-Src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Mol. Carcinog. 33: 146-155.
    • (2002) Mol. Carcinog. , vol.33 , pp. 146-155
    • Matsumoto, T.1
  • 12
    • 0022841074 scopus 로고
    • Critical genetic determinants and molecular events in multistage skin carcinogenesis
    • Slaga, T.J. et al 1986. Critical genetic determinants and molecular events in multistage skin carcinogenesis. Symp. Fundam. Cancer Res. 39: 31-44.
    • (1986) Symp. Fundam. Cancer Res. , vol.39 , pp. 31-44
    • Slaga, T.J.1
  • 13
    • 38649140157 scopus 로고    scopus 로고
    • Activation of Src-family tyrosine kinases in hyperproliferative epidermal disorders
    • Ayli, E.E. et al 2008. Activation of Src-family tyrosine kinases in hyperproliferative epidermal disorders. J. Cutan. Pathol. 35: 273-277.
    • (2008) J. Cutan. Pathol. , vol.35 , pp. 273-277
    • Ayli, E.E.1
  • 14
    • 0041940113 scopus 로고    scopus 로고
    • Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis
    • Matsumoto, T. et al 2003. Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis. Cancer Res. 63: 4819-4828.
    • (2003) Cancer Res. , vol.63 , pp. 4819-4828
    • Matsumoto, T.1
  • 15
    • 0029079944 scopus 로고
    • Fyn tyrosine kinase is involved in keratinocyte differentiation control
    • Calautti, E. et al 1995. Fyn tyrosine kinase is involved in keratinocyte differentiation control. Genes Dev. 9: 2279-2291.
    • (1995) Genes Dev. , vol.9 , pp. 2279-2291
    • Calautti, E.1
  • 16
    • 10344258041 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase cascade to treat cancer
    • Sebolt-Leopold, J.S. & R. Herrera 2004. Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat. Rev. Cancer 4: 937-947.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 937-947
    • Sebolt-Leopold, J.S.1    Herrera, R.2
  • 17
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb, M.H. & E.J. Goldsmith 1995. How MAP kinases are regulated. J. Biol. Chem. 270: 14843-14846.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 18
    • 0029559183 scopus 로고
    • The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
    • Sundaram, M. & M. Han 1995. The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83: 889-901.
    • (1995) Cell , vol.83 , pp. 889-901
    • Sundaram, M.1    Han, M.2
  • 19
    • 0035024784 scopus 로고    scopus 로고
    • UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes
    • Djavaheri-Mergny, M. & L. Dubertret 2001. UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes. Exp. Dermatol. 10: 204-210.
    • (2001) Exp. Dermatol. , vol.10 , pp. 204-210
    • Djavaheri-Mergny, M.1    Dubertret, L.2
  • 20
    • 2442689239 scopus 로고    scopus 로고
    • Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate
    • Rodriguez-Viciana, P., C. Sabatier & F. McCormick 2004. Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate. Mol. Cell Biol. 24: 4943-4954.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 4943-4954
    • Rodriguez-Viciana, P.1    Sabatier, C.2    McCormick, F.3
  • 21
    • 0037189575 scopus 로고    scopus 로고
    • Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids
    • Hoyos, B. et al 2002. Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids. J. Biol. Chem. 277: 23949-23957.
    • (2002) J. Biol. Chem. , vol.277 , pp. 23949-23957
    • Hoyos, B.1
  • 22
    • 4043139430 scopus 로고    scopus 로고
    • Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling
    • Huntington, J.T. et al 2004. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling. J. Biol. Chem. 279: 33168-33176.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33168-33176
    • Huntington, J.T.1
  • 23
    • 0037194728 scopus 로고    scopus 로고
    • Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
    • Rajagopalan, H. et al 2002. Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature 418: 934.
    • (2002) Nature , vol.418 , pp. 934
    • Rajagopalan, H.1
  • 24
    • 34447096817 scopus 로고    scopus 로고
    • Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms
    • Cho, H.J. et al 2007. Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. Carcinogenesis 28: 1104-1110.
    • (2007) Carcinogenesis , vol.28 , pp. 1104-1110
    • Cho, H.J.1
  • 25
    • 34248597048 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase kinase 4 in cancer
    • Whitmarsh, A.J. & R.J. Davis 2007. Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene 26: 3172-3184.
    • (2007) Oncogene , vol.26 , pp. 3172-3184
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 26
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L.C. 2002. The phosphoinositide 3-kinase pathway. Science 296: 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 27
    • 51849111556 scopus 로고    scopus 로고
    • PI3K pathway alterations in cancer: variations on a theme
    • Yuan, T.L. & L.C. Cantley 2008. PI3K pathway alterations in cancer: variations on a theme. Oncogene 27: 5497-5510.
    • (2008) Oncogene , vol.27 , pp. 5497-5510
    • Yuan, T.L.1    Cantley, L.C.2
  • 28
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • Engelman, J.A., J. Luo & L.C. Cantley 2006. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet 7: 606-619.
    • (2006) Nat. Rev. Genet , vol.7 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 29
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels, Y. et al 2004. High frequency of mutations of the PIK3CA gene in human cancers. Science 304: 554.
    • (2004) Science , vol.304 , pp. 554
    • Samuels, Y.1
  • 30
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet, A. et al 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 31
    • 66449118214 scopus 로고    scopus 로고
    • Switching Akt: from survival signaling to deadly response
    • Los, M. et al 2009. Switching Akt: from survival signaling to deadly response. Bioessays 31: 492-495.
    • (2009) Bioessays , vol.31 , pp. 492-495
    • Los, M.1
  • 32
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes, O.N. et al 1999. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401: 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1
  • 34
    • 0034693871 scopus 로고    scopus 로고
    • Janus kinases: components of multiple signaling pathways
    • Rane, S.G. & E.P. Reddy 2000. Janus kinases: components of multiple signaling pathways. Oncogene 19: 5662-5679.
    • (2000) Oncogene , vol.19 , pp. 5662-5679
    • Rane, S.G.1    Reddy, E.P.2
  • 35
    • 0034658698 scopus 로고    scopus 로고
    • STATs in oncogenesis
    • Bowman, T. et al 2000. STATs in oncogenesis. Oncogene 19: 2474-2488.
    • (2000) Oncogene , vol.19 , pp. 2474-2488
    • Bowman, T.1
  • 36
    • 33645839013 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription (STATs): novel targets of chemopreventive and chemotherapeutic drugs
    • Klampfer, L. 2006. Signal transducers and activators of transcription (STATs): novel targets of chemopreventive and chemotherapeutic drugs. Curr. Cancer Drug Targets 6: 107-121.
    • (2006) Curr. Cancer Drug Targets , vol.6 , pp. 107-121
    • Klampfer, L.1
  • 37
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: structural, cellular, and molecular biology
    • Smith, W.L., D.L. DeWitt & R.M. Garavito 2000. Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69: 145-182.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 38
    • 0035963309 scopus 로고    scopus 로고
    • Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes
    • Chen, W. et al 2001. Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene 20: 3921-3926.
    • (2001) Oncogene , vol.20 , pp. 3921-3926
    • Chen, W.1
  • 39
    • 0142219780 scopus 로고    scopus 로고
    • Cyclooxygenases in the skin: pharmacological and toxicological implications
    • Lee, J.L. et al 2003. Cyclooxygenases in the skin: pharmacological and toxicological implications. Toxicol. Appl. Pharmacol. 192: 294-306.
    • (2003) Toxicol. Appl. Pharmacol. , vol.192 , pp. 294-306
    • Lee, J.L.1
  • 40
    • 0032815072 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis
    • Fischer, S.M. et al 1999. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol. Carcinog. 25: 231-240.
    • (1999) Mol. Carcinog. , vol.25 , pp. 231-240
    • Fischer, S.M.1
  • 41
    • 34248360733 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis
    • Fischer, S.M. et al 2007. Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis. Mol. Carcinog. 46: 363-371.
    • (2007) Mol. Carcinog. , vol.46 , pp. 363-371
    • Fischer, S.M.1
  • 42
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D. & J. Folkman 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 43
    • 0035254648 scopus 로고    scopus 로고
    • Angiogenesis: regulators and clinical applications
    • Liekens, S., E. De Clercq & J. Neyts 2001. Angiogenesis: regulators and clinical applications. Biochem. Pharmacol. 61: 253-270.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 253-270
    • Liekens, S.1    De Clercq, E.2    Neyts, J.3
  • 44
    • 7144264398 scopus 로고    scopus 로고
    • Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice
    • Detmar, M. et al 1998. Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J. Invest. Dermatol. 111: 1-6.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 1-6
    • Detmar, M.1
  • 45
    • 39649085541 scopus 로고    scopus 로고
    • Extracellular matrix and HIF-1 signaling: the role of prolidase
    • Surazynski, A. et al 2008. Extracellular matrix and HIF-1 signaling: the role of prolidase. Int. J. Cancer 122: 1435-1440.
    • (2008) Int. J. Cancer , vol.122 , pp. 1435-1440
    • Surazynski, A.1
  • 46
    • 20344361933 scopus 로고    scopus 로고
    • Metalloproteinases and their inhibitors in tumor angiogenesis
    • Handsley, M.M. & D.R. Edwards 2005. Metalloproteinases and their inhibitors in tumor angiogenesis. Int. J. Cancer. 115: 849-860.
    • (2005) Int. J. Cancer. , vol.115 , pp. 849-860
    • Handsley, M.M.1    Edwards, D.R.2
  • 47
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe, J.A. et al 1996. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16: 4604-4613.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1
  • 48
    • 15444342958 scopus 로고    scopus 로고
    • Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
    • Iyer, N.V. et al 1998. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev. 12: 149-162.
    • (1998) Genes Dev. , vol.12 , pp. 149-162
    • Iyer, N.V.1
  • 49
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • Ryan, H.E., J. Lo & R.S. Johnson 1998. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 17: 3005-3015.
    • (1998) EMBO J. , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 50
    • 24744434146 scopus 로고    scopus 로고
    • Masters of angiogenesis
    • Strieter, R.M. 2005. Masters of angiogenesis. Nat. Med. 11: 925-927.
    • (2005) Nat. Med. , vol.11 , pp. 925-927
    • Strieter, R.M.1
  • 51
    • 0036006453 scopus 로고    scopus 로고
    • Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
    • Pai, R. et al 2002. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat. Med. 8: 289-293.
    • (2002) Nat. Med. , vol.8 , pp. 289-293
    • Pai, R.1
  • 52
    • 36749032385 scopus 로고    scopus 로고
    • Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B
    • Lee, K.M. et al 2007. Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B. J. Agric. Food Chem. 55: 9678-9684.
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 9678-9684
    • Lee, K.M.1
  • 53
    • 34848916118 scopus 로고    scopus 로고
    • Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1
    • Lee, K.W. et al 2007. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis 28: 1918-1927.
    • (2007) Carcinogenesis , vol.28 , pp. 1918-1927
    • Lee, K.W.1
  • 54
    • 58549107213 scopus 로고    scopus 로고
    • Myricetin directly targets JAK1 to inhibit cell transformation
    • Kumamoto, T., M. Fujii & D.X. Hou 2009. Myricetin directly targets JAK1 to inhibit cell transformation. Cancer Lett. 275: 17-26.
    • (2009) Cancer Lett. , vol.275 , pp. 17-26
    • Kumamoto, T.1    Fujii, M.2    Hou, D.X.3
  • 55
    • 70450286260 scopus 로고    scopus 로고
    • Akt is a direct target for myricetin to inhibit cell transformation
    • Kumamoto, T., M. Fujii & D.X. Hou 2009. Akt is a direct target for myricetin to inhibit cell transformation. Mol. Cell Biochem. 332: 33-41.
    • (2009) Mol. Cell Biochem. , vol.332 , pp. 33-41
    • Kumamoto, T.1    Fujii, M.2    Hou, D.X.3
  • 56
    • 58249129942 scopus 로고    scopus 로고
    • MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin
    • Kim, J.E. et al 2009. MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin. Biochem. Pharmacol. 77: 412-421.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 412-421
    • Kim, J.E.1
  • 57
    • 48649090159 scopus 로고    scopus 로고
    • Myricetin suppresses UVB-induced skin cancer by targeting Fyn
    • Jung, S.K. et al 2008. Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Res. 68: 6021-6029.
    • (2008) Cancer Res. , vol.68 , pp. 6021-6029
    • Jung, S.K.1
  • 58
    • 0000933858 scopus 로고
    • Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene
    • Buening, M.K. et al 1978. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7, 8-diol-9, 10-epoxides in newborn mice: exceptional activity of (+)-7beta, 8alpha-dihydroxy-9alpha, 10alpha-epoxy-7, 8, 9, 10-tetrahydrobenzo[a]pyrene. Proc. Natl. Acad. Sci. USA 75: 5358-5361.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 5358-5361
    • Buening, M.K.1
  • 59
    • 0023927609 scopus 로고
    • Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, andN-methyl-N-nitrosourea-induced skin tumorigenesis in mice
    • Mukhtar, H. et al 1988. Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7, 12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, andN-methyl-N-nitrosourea-induced skin tumorigenesis in mice. Cancer Res. 48: 2361-2365.
    • (1988) Cancer Res. , vol.48 , pp. 2361-2365
    • Mukhtar, H.1
  • 60
    • 0020694155 scopus 로고
    • Formation of benzo(a)pyrene/DNA adducts and their relationship to tumor initiation in mouse epidermis
    • Ashurst, S.W. et al 1983. Formation of benzo(a)pyrene/DNA adducts and their relationship to tumor initiation in mouse epidermis. Cancer Res. 43: 1024-1029.
    • (1983) Cancer Res. , vol.43 , pp. 1024-1029
    • Ashurst, S.W.1
  • 61
    • 0023113476 scopus 로고
    • Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols
    • Das, M. et al 1987. Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols. Cancer Res. 47: 760-766.
    • (1987) Cancer Res. , vol.47 , pp. 760-766
    • Das, M.1
  • 62
    • 0037735453 scopus 로고    scopus 로고
    • UV-induced skin damage
    • Ichihashi, M. et al 2003. UV-induced skin damage. Toxicology 189: 21-39.
    • (2003) Toxicology , vol.189 , pp. 21-39
    • Ichihashi, M.1
  • 63
    • 77953963632 scopus 로고    scopus 로고
    • Myricetin inhibits Akt survival signaling and induces Bad-mediated apoptosis in a low dose ultraviolet (UV)-B-irradiated HaCaT human immortalized keratinocytes
    • Kim, W. et al 2010. Myricetin inhibits Akt survival signaling and induces Bad-mediated apoptosis in a low dose ultraviolet (UV)-B-irradiated HaCaT human immortalized keratinocytes. J. Radiat. Res. 51: 285-296.
    • (2010) J. Radiat. Res. , vol.51 , pp. 285-296
    • Kim, W.1
  • 64
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers, G. & L.E. Benjamin 2003. Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3: 401-410.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 65
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P. & R.K. Jain 2000. Angiogenesis in cancer and other diseases. Nature 407: 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 66
    • 77952317417 scopus 로고    scopus 로고
    • Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo
    • Jung, S.K. et al 2010. Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo. Carcinogenesis 31: 911-917.
    • (2010) Carcinogenesis , vol.31 , pp. 911-917
    • Jung, S.K.1
  • 67
    • 0000499063 scopus 로고
    • Alterations in human dermal connective tissue with age and chronic sun damage
    • Smith, J.G., Jr. et al 1962. Alterations in human dermal connective tissue with age and chronic sun damage. J. Invest. Dermatol. 39: 347-350.
    • (1962) J. Invest. Dermatol. , vol.39 , pp. 347-350
    • Smith Jr, J.G.1
  • 68
    • 0035724961 scopus 로고    scopus 로고
    • Modulation of skin collagen metabolism in aged and photoaged human skin in vivo
    • Chung, J.H. et al 2001. Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J. Invest. Dermatol. 117: 1218-1224.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1218-1224
    • Chung, J.H.1
  • 69
    • 0027424515 scopus 로고
    • Analysis of the mechanism of ultraviolet (UV) B radiation-induced prostaglandin E2 synthesis by human epidermoid carcinoma cells
    • Grewe, M. et al 1993. Analysis of the mechanism of ultraviolet (UV) B radiation-induced prostaglandin E2 synthesis by human epidermoid carcinoma cells. J. Invest. Dermatol. 101: 528-531.
    • (1993) J. Invest. Dermatol. , vol.101 , pp. 528-531
    • Grewe, M.1
  • 71
    • 34147112900 scopus 로고    scopus 로고
    • Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast
    • Sim, G.S. et al 2007. Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast. Arch. Pharm. Res. 30: 290-298.
    • (2007) Arch. Pharm. Res. , vol.30 , pp. 290-298
    • Sim, G.S.1
  • 72
    • 72149113330 scopus 로고    scopus 로고
    • Protective effects of myricetin against ultraviolet-B-induced damage in human keratinocytes
    • Huang, J.H. et al 2010. Protective effects of myricetin against ultraviolet-B-induced damage in human keratinocytes. Toxicol. In Vitro. 24: 21-28.
    • (2010) Toxicol. In Vitro. , vol.24 , pp. 21-28
    • Huang, J.H.1
  • 73
    • 77649181352 scopus 로고    scopus 로고
    • Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf
    • Jung, S.K. et al 2010. Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf. Biochem. Pharmacol. 79: 1455-1461.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1455-1461
    • Jung, S.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.