Comparative analysis of different peptidyl-prolyl isomerases reveals FK506-binding protein 12 as the most potent enhancer of α-synuclein aggregation

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26687-26701

  Deleersnijder, Angélique ^a   Van Rompuy, Anne Sophie ^a   Desender, Linda ^a   Pottel, Hans ^b   Buée, Luc ^d,e,f   Debyser, Zeger ^a,c   Baekelandt, Veerle ^a   Gerard, Melanie ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Universitaire Campus   (Belgium)

^c DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^d JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^e UNIV LILLE   (France)

^f LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; COMPARATIVE ANALYSIS; CYCLOPHILIN A; DRUG TARGETS; FIBRIL FORMATION; FK506-BINDING PROTEINS; IMMUNOPHILINS; IN-VITRO; ISOMERASES; MECHANISM OF ACTION; NEURONAL CELL CULTURE; OVER-EXPRESSION; PARKINSON DISEASE; PEPTIDYL-PROLYL ISOMERASE; SYNUCLEIN;

CATALYSTS; CELL DEATH; ENZYMES; PROTEIN FOLDING; PROTEINS;

CELL CULTURE;

ALPHA SYNUCLEIN; CYCLOPHILIN A; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 12; FK 506 BINDING PROTEIN 38; FK 506 BINDING PROTEIN 52; FK 506 BINDING PROTEIN 65; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE PIN1; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROFILAMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ALPHA-SYNUCLEIN; CELL DEATH; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GENE KNOCKDOWN TECHNIQUES; HUMANS; NEURONS; PARKINSON DISEASE; PEPTIDYLPROLYL ISOMERASE; TACROLIMUS BINDING PROTEIN 1A;

EID: 79960692455     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.182303     Document Type: Article

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