High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

Antiviral Research

Volumn 91, Issue 3, 2011, Pages 241-251

  Campagnola, Grace ^a   Gong, Peng ^a   Peersen, Olve B ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

HTS; Inhibitor; Poliovirus; RdRP; RNA; RNA dependent RNA polymerase

Indexed keywords

BASE; NUCLEOTIDE; RNA DIRECTED RNA POLYMERASE INHIBITOR; VIRUS RNA;

ALLOSTERISM; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; DATA ANALYSIS; EXPERIMENT; FLUORESCENCE; HIGH THROUGHPUT SCREENING; IC 50; KINETICS; MEDICAL RECORD; NONHUMAN; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; RNA BINDING; VALIDATION PROCESS; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLUORESCENCE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; NUCLEOTIDES; POLIOMYELITIS; POLIOVIRUS; PROTEIN BINDING; RNA REPLICASE; RNA, VIRAL; SMALL MOLECULE LIBRARIES; VIRUS REPLICATION;

POLIOVIRUS; RNA VIRUSES;

EID: 79960473677     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2011.06.006     Document Type: Article

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