Tobacco as biofactory for biologically active hPL production: A human hormone with potential applications in type-1 diabetes

Transgenic Research

Volumn 20, Issue 4, 2011, Pages 721-733

  Urreta, Iratxe ^a   Oyanguren, Iñigo ^b   Castañón, Sonia ^a  

^a NEIKER and a Vaccine producing Commercial Company CZVSL   (Spain)

^b Guserbiot SL Parque Industrial de Júndiz ^*  (Spain)

Author keywords

Endoplasmic reticulum (ER) retention; Genetic transformation; Human placental lactogen; Molecular farming; Tobacco plants; Type 1 diabetes

Indexed keywords

PLACENTA LACTOGEN; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE VECTOR; GENETICS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION; TOBACCO; TRANSGENIC PLANT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 1; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENETIC VECTORS; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; PLACENTAL LACTOGEN; PLANTS, GENETICALLY MODIFIED; PROTEIN STABILITY; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOBACCO;

NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM; RATTUS;

EID: 79960459987     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-010-9452-z     Document Type: Article

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