Expression and characterization of an anti-(hepatitis B surface antigen) glycosylated mouse antibody in transgenic tobacco (Nicotiana tabacum) plants and its use in the immunopurification of its target antigen

Biotechnology and Applied Biochemistry

Volumn 38, Issue 3, 2003, Pages 223-230

  Ramírez, Nadia ^a   Rodríguez, Meilyn ^a   Ayala, Marta ^a   Cremata, José ^a   Pérez, Marlene ^a   Martínez, Anazuria ^a   Linares, Marbelis ^a   Hevia, Yasser ^a   Páez, Rolando ^a   Valdés, Rodolfo ^a   Gavilondo, Jorge V ^a   Selman Housein, Guillermo ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Immunopurification; N glycosylation; Plantibody; Protein assembly; Recombinant antibody; Transgenic tobacco (Nicotiana tabacum)

Indexed keywords

ANTIBODIES; IMMUNOLOGY; PLANTS (BOTANY); PURIFICATION; TOBACCO; VACCINES;

GLYCOSYLATION;

ANTIGENS;

HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G1; LYSYLASPARTYLGLUTAMINYLLEUCINE; MONOCLONAL ANTIBODY; SEPHAROSE; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ANTIBODY ISOLATION; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CHROMATOGRAPHY; DRUG ISOLATION; DRUG MANUFACTURE; ENDOPLASMIC RETICULUM; GENE CONSTRUCT; GENE EXPRESSION; GLYCOSYLATION; GOLGI COMPLEX; NONHUMAN; PLANT LEAF; PROTEIN DOMAIN; PURIFICATION; SWEET POTATO; TOBACCO; TRANSGENIC PLANT;

ANIMALS; ANTIBODIES, MONOCLONAL; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, PLANT; GLYCOSYLATION; HEPATITIS B ANTIBODIES; IMMUNOASSAY; MICE; MICE, INBRED BALB C; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; TOBACCO; VACCINES, SYNTHETIC;

HEPATITIS B VIRUS; IPOMOEA BATATAS; NICOTIANA TABACUM; SOLANUM TUBEROSUM; TABACUM;

EID: 0347478147     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20030028     Document Type: Article

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