-
1
-
-
70349338616
-
A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry
-
Baleux, F., et al. 2009. A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry. Nat. Chem. Biol. 5:743-748.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 743-748
-
-
Baleux, F.1
-
2
-
-
0027253445
-
A spring-loaded mechanism for the conformational change of influenza hemagglutinin
-
Carr, C. M., and P. S. Kim. 1993. A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell 73:823-832.
-
(1993)
Cell
, vol.73
, pp. 823-832
-
-
Carr, C.M.1
Kim, P.S.2
-
3
-
-
65749085502
-
Chapter 7, Tyrosine sulfation of HIV-1 coreceptors and other chemokine receptors
-
Choe, H., and M. Farzan. 2009. Chapter 7. Tyrosine sulfation of HIV-1 coreceptors and other chemokine receptors. Methods Enzymol. 461:147-170.
-
(2009)
Methods Enzymol
, vol.461
, pp. 147-170
-
-
Choe, H.1
Farzan, M.2
-
4
-
-
33750867503
-
Tyrosine sulfate trapped by amber
-
Choe, H., and M. Farzan. 2006. Tyrosine sulfate trapped by amber. Nat. Biotechnol. 24:1361-1362.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1361-1362
-
-
Choe, H.1
Farzan, M.2
-
5
-
-
0005014748
-
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
Choe, H., et al. 1996. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135-1148.
-
(1996)
Cell
, vol.85
, pp. 1135-1148
-
-
Choe, H.1
-
6
-
-
0042855800
-
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120
-
Choe, H., et al. 2003. Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120. Cell 114:161-170.
-
(2003)
Cell
, vol.114
, pp. 161-170
-
-
Choe, H.1
-
7
-
-
0031575431
-
Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals
-
Connor, R. I., K. E. Sheridan, D. Ceradini, S. Choe, and N. R. Landau. 1997. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals. J. Exp. Med. 185:621-628.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 621-628
-
-
Connor, R.I.1
Sheridan, K.E.2
Ceradini, D.3
Choe, S.4
Landau, N.R.5
-
8
-
-
0035000023
-
Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes
-
Cormier, E. G., D. N. Tran, L. Yukhayeva, W. C. Olson, and T. Dragic. 2001. Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes. J. Virol. 75:5541-5549.
-
(2001)
J. Virol.
, vol.75
, pp. 5541-5549
-
-
Cormier, E.G.1
Tran, D.N.2
Yukhayeva, L.3
Olson, W.C.4
Dragic, T.5
-
9
-
-
20844448731
-
Antigenic conservation and immunogenicity of the HIV coreceptor binding site
-
Decker, J. M., et al. 2005. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J. Exp. Med. 201:1407-1419.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1407-1419
-
-
Decker, J.M.1
-
10
-
-
0037372301
-
Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor
-
Dey, B., C. S. Del Castillo, and E. A. Berger. 2003. Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor. J. Virol. 77:2859-2865.
-
(2003)
J. Virol.
, vol.77
, pp. 2859-2865
-
-
Dey, B.1
Del Castillo, C.S.2
Berger, E.A.3
-
11
-
-
0030770546
-
Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry
-
Doms, R. W., and S. C. Peiper. 1997. Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry. Virology 235:179-190.
-
(1997)
Virology
, vol.235
, pp. 179-190
-
-
Doms, R.W.1
Peiper, S.C.2
-
12
-
-
33749410635
-
A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection
-
Dorfman, T., M. J. Moore, A. C. Guth, H. Choe, and M. Farzan. 2006. A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection. J. Biol. Chem. 281:28529-28535.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28529-28535
-
-
Dorfman, T.1
Moore, M.J.2
Guth, A.C.3
Choe, H.4
Farzan, M.5
-
13
-
-
15844389650
-
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
-
Dragic, T., et al. 1996. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667-673.
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
-
14
-
-
0034924823
-
Mechanisms of viral membrane fusion and its inhibition
-
Eckert, D. M., and P. S. Kim. 2001. Mechanisms of viral membrane fusion and its inhibition. Annu. Rev. Biochem. 70:777-810.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 777-810
-
-
Eckert, D.M.1
Kim, P.S.2
-
15
-
-
2142710315
-
The role of post-translational modifications of the CXCR4 amino-terminus in SDF-1a association and HIV-1 entry
-
Farzan, M., et al. 2002. The role of post-translational modifications of the CXCR4 amino-terminus in SDF-1a association and HIV-1 entry. J. Biol. Chem. 28:28.
-
(2002)
J. Biol. Chem.
, vol.28
, pp. 28
-
-
Farzan, M.1
-
16
-
-
0031883554
-
A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5
-
Farzan, M., et al. 1998. A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5. J. Virol. 72:1160-1164.
-
(1998)
J. Virol.
, vol.72
, pp. 1160-1164
-
-
Farzan, M.1
-
17
-
-
0033525590
-
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry
-
Farzan, M., et al. 1999. Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. Cell 96:667-676.
-
(1999)
Cell
, vol.96
, pp. 667-676
-
-
Farzan, M.1
-
18
-
-
0035821247
-
Sulfated tyrosines contribute to the formation of the C5a docking site of the human C5a anaphylatoxin receptor
-
Farzan, M., et al. 2001. Sulfated tyrosines contribute to the formation of the C5a docking site of the human C5a anaphylatoxin receptor. J. Exp. Med. 193:1059-1066.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1059-1066
-
-
Farzan, M.1
-
19
-
-
0034721834
-
A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry
-
Farzan, M., et al. 2000. A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry. J. Biol. Chem. 275:33516-33521.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33516-33521
-
-
Farzan, M.1
-
20
-
-
0030002637
-
HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G proteincoupled receptor
-
Feng, Y., C. C. Broder, P. E. Kennedy, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G proteincoupled receptor. Science 272:872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
21
-
-
0031959601
-
Capture of an early fusion-active conformation of HIV-1 gp41
-
Furuta, R. A., C. T. Wild, Y. Weng, and C. D. Weiss. 1998. Capture of an early fusion-active conformation of HIV-1 gp41. Nat. Struct. Biol. 5:276-279.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 276-279
-
-
Furuta, R.A.1
Wild, C.T.2
Weng, Y.3
Weiss, C.D.4
-
22
-
-
34848868199
-
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
-
Huang, C. C., et al. 2007. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science 317:1930-1934.
-
(2007)
Science
, vol.317
, pp. 1930-1934
-
-
Huang, C.C.1
-
23
-
-
21044438453
-
Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth
-
Huang, C. C., et al. 2005. Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure 13:755-768.
-
(2005)
Structure
, vol.13
, pp. 755-768
-
-
Huang, C.C.1
-
24
-
-
68349150945
-
Vector-mediated gene transfer engenders longlived neutralizing activity and protection against SIV infection in monkeys
-
Johnson, P. R., et al. 2009. Vector-mediated gene transfer engenders longlived neutralizing activity and protection against SIV infection in monkeys. Nat. Med. 15:901-906.
-
(2009)
Nat. Med.
, vol.15
, pp. 901-906
-
-
Johnson, P.R.1
-
25
-
-
38349081511
-
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
-
Karlsson Hedestam, G. B., et al. 2008. The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nat. Rev. Microbiol. 6:143-155.
-
(2008)
Nat. Rev. Microbiol.
, vol.6
, pp. 143-155
-
-
Karlsson Hedestam, G.B.1
-
26
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong, P. D., et al. 1998. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393:648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
-
27
-
-
0141521564
-
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1
-
Labrijn, A. F., et al. 2003. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. J. Virol. 77:10557-10565.
-
(2003)
J. Virol.
, vol.77
, pp. 10557-10565
-
-
Labrijn, A.F.1
-
28
-
-
33746689169
-
A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses
-
Liao, H. X., et al. 2006. A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology 353:268-282.
-
(2006)
Virology
, vol.353
, pp. 268-282
-
-
Liao, H.X.1
-
29
-
-
70349095953
-
Mutagenesis and evolution of sulfated antibodies using an expanded genetic code
-
Liu, C. C., H. Choe, M. Farzan, V. V. Smider, and P. G. Schultz. 2009. Mutagenesis and evolution of sulfated antibodies using an expanded genetic code. Biochemistry 48:8891-8898.
-
(2009)
Biochemistry
, vol.48
, pp. 8891-8898
-
-
Liu, C.C.1
Choe, H.2
Farzan, M.3
Smider, V.V.4
Schultz, P.G.5
-
30
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
Liu, J., A. Bartesaghi, M. J. Borgnia, G. Sapiro, and S. Subramaniam. 2008. Molecular architecture of native HIV-1 gp120 trimers. Nature 455:109-113.
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
31
-
-
12644288298
-
Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains
-
Lu, Z., et al. 1997. Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proc. Natl. Acad. Sci. U. S. A. 94:6426-6431.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 6426-6431
-
-
Lu, Z.1
-
32
-
-
12244281787
-
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
-
Martin, L., et al. 2003. Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes. Nat. Biotechnol. 21:71-76.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 71-76
-
-
Martin, L.1
-
33
-
-
1642391068
-
Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes
-
Matthews, T., et al. 2004. Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes. Nat. Rev. Drug Discov. 3:215-225.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 215-225
-
-
Matthews, T.1
-
34
-
-
77954912140
-
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
-
Pejchal, R., et al. 2010. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc. Natl. Acad. Sci. U. S. A. 107:11483-11488.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 11483-11488
-
-
Pejchal, R.1
-
35
-
-
0032546952
-
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
-
Rizzuto, C. D., et al. 1998. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science 280:1949-1953.
-
(1998)
Science
, vol.280
, pp. 1949-1953
-
-
Rizzuto, C.D.1
-
36
-
-
16044365432
-
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity
-
Rucker, J., et al. 1996. Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity. Cell 87:437-446.
-
(1996)
Cell
, vol.87
, pp. 437-446
-
-
Rucker, J.1
-
37
-
-
11144358392
-
Small-molecule inhibitors of HIV-1 entry block receptorinduced conformational changes in the viral envelope glycoproteins
-
Si, Z., et al. 2004. Small-molecule inhibitors of HIV-1 entry block receptorinduced conformational changes in the viral envelope glycoproteins. Proc. Natl. Acad. Sci. U. S. A. 101:5036-5041.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 5036-5041
-
-
Si, Z.1
-
38
-
-
23944451595
-
A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic
-
Stricher, F., et al. 2005. A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic. Biochem. J. 390:29-39.
-
(2005)
Biochem. J.
, vol.390
, pp. 29-39
-
-
Stricher, F.1
-
39
-
-
0031878761
-
Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies
-
Sullivan, N., et al. 1998. Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies. J. Virol. 72:6332-6338.
-
(1998)
J. Virol.
, vol.72
, pp. 6332-6338
-
-
Sullivan, N.1
-
40
-
-
16144365317
-
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
-
Trkola, A., et al. 1996. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature 384:184-187.
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
-
41
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker, L. M., et al. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
-
42
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn, W., A. Dessen, S. C. Harrison, J. J. Skehel, and D. C. Wiley. 1997. Atomic structure of the ectodomain from HIV-1 gp41. Nature 387: 426-430.
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
Skehel, J.J.4
Wiley, D.C.5
-
43
-
-
72849116535
-
Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents
-
West, A. P., Jr., et al. 2010. Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents. J. Virol. 84:261-269.
-
(2010)
J. Virol.
, vol.84
, pp. 261-269
-
-
West Jr., A.P.1
-
44
-
-
0942298133
-
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2
-
Wong, S. K., W. Li, M. J. Moore, H. Choe, and M. Farzan. 2004. A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2. J. Biol. Chem. 279:3197-3201.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3197-3201
-
-
Wong, S.K.1
Li, W.2
Moore, M.J.3
Choe, H.4
Farzan, M.5
-
45
-
-
16144365650
-
CD4-induced interactions of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
-
Wu, L., et al. 1996. CD4-induced interactions of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature 184:179-183.
-
(1996)
Nature
, vol.184
, pp. 179-183
-
-
Wu, L.1
-
46
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt, R., et al. 1998. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 393:705-711.
-
(1998)
Nature
, vol.393
, pp. 705-711
-
-
Wyatt, R.1
|