A PET brain reporter gene system based on type 2 cannabinoid receptors

Journal of Nuclear Medicine

Volumn 52, Issue 7, 2011, Pages 1102-1109

  Vandeputte, Caroline ^a,b,c   Evens, Nele ^c   Toelen, Jaan ^d   Deroose, Christophe M ^a,b   Bosier, Barbara ^e   Ibrahimi, Abdelilah ^b,d   Van Der Perren, Anke ^c   Gijsbers, Rik ^d   Janssen, Peter ^f   Lambert, Didier M ^e   Verbruggen, Alfons ^b,c   Debyser, Zeger ^b,d   Bormans, Guy ^b,c   Baekelandt, Veerle ^b,c   Van Laere, Koen ^a,b  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b KU Leuven   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^e UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^f KU LEUVEN UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

11C GW405833; Brain; CB2 receptor; Positron emission tomography; Reporter gene

Indexed keywords

1 (2,3 DICHLOROBENZOYL) 5 METHOXY 2 METHYL 3 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 2 RECEPTOR; CARBON 11; ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BLOOD BRAIN BARRIER; CELL CULTURE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DISTRIBUTION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC ENGINEERING; HAPLORHINI; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; REPORTER GENE; SPECIES DIFFERENCE;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; DEPENDOVIRUS; GENES, REPORTER; GENETIC ENGINEERING; GENETIC VECTORS; HEK293 CELLS; HUMANS; INDOLES; MALE; MICE; MORPHOLINES; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RATS; RECEPTOR, CANNABINOID, CB2; REPRODUCIBILITY OF RESULTS; SPECIES SPECIFICITY;

EID: 79960324391     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.110.084426     Document Type: Article

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