Sustained liver-specific transgene expression from the albumin promoter in mice following hydrodynamic plasmid DNA delivery

Journal of Gene Medicine

Volumn 10, Issue 5, 2008, Pages 551-563

  Wooddell, Christine I ^a   Reppen, Thomas ^a   Wolff, Jon A ^a,b   Herweijer, Hans ^a  

^a Mirus Bio Corporation   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Hydrodynamic delivery; Liver; Plasmid DNA; Sustained expression

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; APOLIPOPROTEIN E3; BLOOD CLOTTING FACTOR 9; CHOLESTEROL;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA VECTOR; DOSE RESPONSE; ENHANCER REGION; EXPRESSION VECTOR; GENE EXPRESSION; HYDRODYNAMICS BASED TRANSFECTION; HYPERCHOLESTEROLEMIA; INTRON; KNOCKOUT MOUSE; LIVER; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TISSUE SPECIFICITY; TRANSGENE;

3' UNTRANSLATED REGIONS; ANIMALS; ENHANCER ELEMENTS (GENETICS); GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; INFUSIONS, INTRAVENOUS; LIVER; MICE; PLASMIDS; PROMOTER REGIONS (GENETICS); SERUM ALBUMIN; TRANSGENES;

CYTOMEGALOVIRUS; MUS;

EID: 44449145951     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1179     Document Type: Article

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