Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation

Molecular Pharmacology

Volumn 80, Issue 2, 2011, Pages 267-280

  Timm, David E ^b   Benveniste, Morris ^c   Weeks, Autumn M ^a   Nisenbaum, Eric S ^b   Partin, Kathryn M ^a  

^a Department of Ecosystem Science and Sustainability   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR AGONIST; CX 614; CYCLOTHIAZIDE; PHENYL 1,4 BIS ALKYLSULFONAMIDE; PHENYL 1,4 BIS CARBOXYTHIOPHENE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EXCITATORY AMINO ACID AGENTS; HEK293 CELLS; HUMANS; OXAZINES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, AMPA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960285866     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.070243     Document Type: Article

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