-
2
-
-
0030025395
-
The impact of receptor desensitization on fast synaptic transmission
-
Jones, M.V. & Westbrook, G.L. The impact of receptor desensitization on fast synaptic transmission. Trends Neurosci. 19, 96-101 (1996).
-
(1996)
Trends Neurosci.
, vol.19
, pp. 96-101
-
-
Jones, M.V.1
Westbrook, G.L.2
-
3
-
-
33644506134
-
Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse
-
Saviane, C. & Silver, R.A. Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse. Nature 439, 983-987 (2006).
-
(2006)
Nature
, vol.439
, pp. 983-987
-
-
Saviane, C.1
Silver, R.A.2
-
4
-
-
0025356566
-
Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons
-
Zorumski, C.F., Thio, L.L., Clark, G.D. & Clifford, D.B. Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons. Neuron 5, 61-66 (1990).
-
(1990)
Neuron
, vol.5
, pp. 61-66
-
-
Zorumski, C.F.1
Thio, L.L.2
Clark, G.D.3
Clifford, D.B.4
-
5
-
-
0030061340
-
AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked
-
David, J.C., Yamada, K.A., Bagwe, M.R. & Goldberg, M.P. AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked. J. Neurosci. 16, 200-209 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 200-209
-
-
David, J.C.1
Yamada, K.A.2
Bagwe, M.R.3
Goldberg, M.P.4
-
6
-
-
0037118049
-
Mechanism of glutamate receptor desensitization
-
Sun, Y. et al. Mechanism of glutamate receptor desensitization. Nature 417, 245-253 (2002).
-
(2002)
Nature
, vol.417
, pp. 245-253
-
-
Sun, Y.1
-
7
-
-
1242293631
-
Regulation of AMPA receptor gating by ligand binding core dimers
-
Horning, M.S. & Mayer, M.L. Regulation of AMPA receptor gating by ligand binding core dimers. Neuron 41, 379-388 (2004).
-
(2004)
Neuron
, vol.41
, pp. 379-388
-
-
Horning, M.S.1
Mayer, M.L.2
-
8
-
-
0027715150
-
Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavlin A
-
Partin, K.M., Patneau, D.K., Winters, C.A., Mayer, M.L. & Buonanno, A. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavlin A. Neuron 11, 1069-1082 (1993).
-
(1993)
Neuron
, vol.11
, pp. 1069-1082
-
-
Partin, K.M.1
Patneau, D.K.2
Winters, C.A.3
Mayer, M.L.4
Buonanno, A.5
-
9
-
-
0028935086
-
Structural determinants of allosteric regulation in alternatively spliced AMPA receptors
-
Partin, K.M., Bowie, D. & Mayer, M.L. Structural determinants of allosteric regulation in alternatively spliced AMPA receptors. Neuron 14, 833-843 (1995).
-
(1995)
Neuron
, vol.14
, pp. 833-843
-
-
Partin, K.M.1
Bowie, D.2
Mayer, M.L.3
-
10
-
-
0032191104
-
A point mutation in the glutamate binding site blocks desensitization of AMPA receptors
-
Stern-Bach, Y., Russo, S., Neuman, M. & Rosenmund, C. A point mutation in the glutamate binding site blocks desensitization of AMPA receptors. Neuron 21, 907-918 (1998).
-
(1998)
Neuron
, vol.21
, pp. 907-918
-
-
Stern-Bach, Y.1
Russo, S.2
Neuman, M.3
Rosenmund, C.4
-
11
-
-
25644454403
-
Mechanism of positive allosteric modulators acting on AMPA receptors
-
Jin, R. et al. Mechanism of positive allosteric modulators acting on AMPA receptors. J. Neurosci. 25, 9027-9036 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 9027-9036
-
-
Jin, R.1
-
12
-
-
30844468842
-
Glutamate-based therapeutic approaches: Ampakines
-
Lynch, G. Glutamate-based therapeutic approaches: ampakines. Curr. Opin. Pharmacol. 6, 82-88 (2006).
-
(2006)
Curr. Opin. Pharmacol.
, vol.6
, pp. 82-88
-
-
Lynch, G.1
-
14
-
-
2442675355
-
Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain
-
Yelshansky, M.V., Sobolevsky, A.I., Jatzke, C. & Wollmuth, L.P. Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain. J. Neurosci. 24, 4728-4736 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 4728-4736
-
-
Yelshansky, M.V.1
Sobolevsky, A.I.2
Jatzke, C.3
Wollmuth, L.P.4
-
15
-
-
0037442510
-
Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization
-
Fleck, M.W., Cornell, E. & Mah, S.J. Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization. J. Neurosci. 23, 1219-1227 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 1219-1227
-
-
Fleck, M.W.1
Cornell, E.2
Mah, S.J.3
-
16
-
-
0033623299
-
Concentration-dependent substate behavior of native AMPA receptors
-
Smith, T.C. & Howe, J.R. Concentration-dependent substate behavior of native AMPA receptors. Nat. Neurosci. 3, 992-997 (2000).
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 992-997
-
-
Smith, T.C.1
Howe, J.R.2
-
17
-
-
0036582716
-
Functional stoichiometry of glutamate receptor desensitization
-
Bowie, D. & Lange, G.D. Functional stoichiometry of glutamate receptor desensitization. J. Neurosci. 22, 3392-3403 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3392-3403
-
-
Bowie, D.1
Lange, G.D.2
-
19
-
-
0033636314
-
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
-
Armstrong, N. & Gouaux, E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core. Neuron 28, 165-181 (2000).
-
(2000)
Neuron
, vol.28
, pp. 165-181
-
-
Armstrong, N.1
Gouaux, E.2
-
20
-
-
0035943408
-
Mechanisms for ligand binding to GluR0 ion channels: Crystal structures of the glutamate and serine complexes and a closed apo state
-
Mayer, M.L., Olson, R. & Gouaux, E. Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J. Mol. Biol. 311, 815-836 (2001).
-
(2001)
J. Mol. Biol.
, vol.311
, pp. 815-836
-
-
Mayer, M.L.1
Olson, R.2
Gouaux, E.3
-
21
-
-
13444281913
-
Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid
-
Nanao, M.H., Green, T., Stern-Bach, Y., Heinemann, S.F. & Choe, S. Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid. Proc. Natl. Acad. Sci. USA 102, 1708-1713 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1708-1713
-
-
Nanao, M.H.1
Green, T.2
Stern-Bach, Y.3
Heinemann, S.F.4
Choe, S.5
-
22
-
-
27744500994
-
Subunit arrangement and function in NMDA receptors
-
Furukawa, H., Singh, S.K., Mancusso, R. & Gouaux, E. Subunit arrangement and function in NMDA receptors. Nature 438, 185-192 (2005).
-
(2005)
Nature
, vol.438
, pp. 185-192
-
-
Furukawa, H.1
Singh, S.K.2
Mancusso, R.3
Gouaux, E.4
-
23
-
-
33644999815
-
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists
-
Mayer, M.L., Ghosal, A., Dolman, N.P. & Jane, D.E. Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J. Neurosci. 26, 2852-2861 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 2852-2861
-
-
Mayer, M.L.1
Ghosal, A.2
Dolman, N.P.3
Jane, D.E.4
-
24
-
-
0024046835
-
Model building of disulfide bonds in proteins with known three-dimensional structure
-
Hazes, B. & Dijkstra, B.W. Model building of disulfide bonds in proteins with known three-dimensional structure. Protein Eng. 2, 119-125 (1988).
-
(1988)
Protein Eng.
, vol.2
, pp. 119-125
-
-
Hazes, B.1
Dijkstra, B.W.2
-
25
-
-
0032192022
-
Activation and desensitization properties of native and recombinant kainate receptors
-
Paternain, A.V., Rodriguez-Moreno, A., Villarroel, A. & Lerma, J. Activation and desensitization properties of native and recombinant kainate receptors. Neuropharmacology 37, 1249-1259 (1998).
-
(1998)
Neuropharmacology
, vol.37
, pp. 1249-1259
-
-
Paternain, A.V.1
Rodriguez-Moreno, A.2
Villarroel, A.3
Lerma, J.4
-
26
-
-
0037088834
-
External anions and cations distinguish between AMPA and kainate receptor gating mechanisms
-
Bowie, D. External anions and cations distinguish between AMPA and kainate receptor gating mechanisms. J. Physiol. (Lond.) 539, 725-733 (2002).
-
(2002)
J. Physiol. (Lond.)
, vol.539
, pp. 725-733
-
-
Bowie, D.1
-
27
-
-
0038625032
-
Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes
-
Armstrong, N., Mayer, M. & Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc. Natl. Acad. Sci. USA 100, 5736-5741 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5736-5741
-
-
Armstrong, N.1
Mayer, M.2
Gouaux, E.3
-
28
-
-
0034653466
-
Regulation of kinetic properties of GluR2 AMPA receptor channels by alternative splicing
-
Koike, M., Tsukada, S., Tsuzuki, K., Kijima, H. & Ozawa, S. Regulation of kinetic properties of GluR2 AMPA receptor channels by alternative splicing. J. Neurosci. 20, 2166-2174 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 2166-2174
-
-
Koike, M.1
Tsukada, S.2
Tsuzuki, K.3
Kijima, H.4
Ozawa, S.5
-
29
-
-
0036968894
-
Structural basis for AMPA receptor activation and ligand selectivity: Crystal structures of five agonist complexes with the GluR2 ligand-binding core
-
Hogner, A. et al. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core. J. Mol. Biol. 322, 93 (2002).
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 93
-
-
Hogner, A.1
-
30
-
-
0043033172
-
Structural basis for partial agonist action at ionotropic glutamate receptors
-
Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F. & Gouaux, E. Structural basis for partial agonist action at ionotropic glutamate receptors. Nat. Neurosci. 6, 803-810 (2003).
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 803-810
-
-
Jin, R.1
Banke, T.G.2
Mayer, M.L.3
Traynelis, S.F.4
Gouaux, E.5
-
31
-
-
13844266202
-
Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
-
Mayer, M.L. Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron 45, 539-552 (2005).
-
(2005)
Neuron
, vol.45
, pp. 539-552
-
-
Mayer, M.L.1
-
32
-
-
7444240214
-
The three-dimensional structure of an ionotropic glutamate receptor reveals a dimer-of-dimers assembly
-
Tichelaar, W., Safferling, M., Keinanen, K., Stark, H. & Madden, D.R. The three-dimensional structure of an ionotropic glutamate receptor reveals a dimer-of-dimers assembly. J. Mol. Biol. 344, 435-442 (2004).
-
(2004)
J. Mol. Biol.
, vol.344
, pp. 435-442
-
-
Tichelaar, W.1
Safferling, M.2
Keinanen, K.3
Stark, H.4
Madden, D.R.5
-
33
-
-
32344443866
-
Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins
-
Nakagawa, T., Cheng, Y., Sheng, M. & Walz, T. Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins. Biol. Chem. 387, 179-187 (2006).
-
(2006)
Biol. Chem.
, vol.387
, pp. 179-187
-
-
Nakagawa, T.1
Cheng, Y.2
Sheng, M.3
Walz, T.4
-
34
-
-
33747054219
-
Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate
-
Weston, M.C., Gertler, C., Mayer, M.L. & Rosenmund, C. Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate. J. Neurosci. 26, 7650-7658 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 7650-7658
-
-
Weston, M.C.1
Gertler, C.2
Mayer, M.L.3
Rosenmund, C.4
-
35
-
-
13444302564
-
Structure and different conformational states of native AMPA receptor complexes
-
Nakagawa, T., Cheng, Y., Ramm, E., Sheng, M. & Walz, T. Structure and different conformational states of native AMPA receptor complexes. Nature 433, 545-549 (2005).
-
(2005)
Nature
, vol.433
, pp. 545-549
-
-
Nakagawa, T.1
Cheng, Y.2
Ramm, E.3
Sheng, M.4
Walz, T.5
-
36
-
-
33749059766
-
Structure of the desensitized state of ionotropic glutamate receptors
-
Armstrong, N., Jasti, J., Beich-Frandsen, M. & Gouaux, E. Structure of the desensitized state of ionotropic glutamate receptors. Cell 127, 85-97 (2006).
-
(2006)
Cell
, vol.127
, pp. 85-97
-
-
Armstrong, N.1
Jasti, J.2
Beich-Frandsen, M.3
Gouaux, E.4
-
37
-
-
2342462388
-
Structure and function of glutamate receptor ion channels
-
Mayer, M.L. & Armstrong, N. Structure and function of glutamate receptor ion channels. Annu. Rev. Physiol. 66, 161-181 (2004).
-
(2004)
Annu. Rev. Physiol.
, vol.66
, pp. 161-181
-
-
Mayer, M.L.1
Armstrong, N.2
-
38
-
-
1442274756
-
Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition
-
Vistica, J. et al. Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition. Anal. Biochem. 326, 234-256 (2004).
-
(2004)
Anal. Biochem.
, vol.326
, pp. 234-256
-
-
Vistica, J.1
-
39
-
-
0034009520
-
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling
-
Schuck, P. Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophys. J. 78, 1606-1619 (2000).
-
(2000)
Biophys. J.
, vol.78
, pp. 1606-1619
-
-
Schuck, P.1
-
41
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project, Number 4
-
Collaborative Computational Project, Number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D Biol. Crystallogr. 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D Biol. Crystallogr.
, vol.50
, pp. 760-763
-
-
-
42
-
-
33646260450
-
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion
-
Painter, J. & Merritt, E.A. Optimal description of a protein structure in terms of multiple groups undergoing TLS motion. Acta Crystallogr. D Biol. Crystallogr. 62, 439-450 (2006).
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 439-450
-
-
Painter, J.1
Merritt, E.A.2
-
43
-
-
0030841587
-
Electron-density map interpretation
-
Jones, T.A. & Kjeldgaard, M. Electron-density map interpretation. Methods Enzymol. 277, 173-208 (1997).
-
(1997)
Methods Enzymol.
, vol.277
, pp. 173-208
-
-
Jones, T.A.1
Kjeldgaard, M.2
-
44
-
-
0002906346
-
-
Kleywegt, G.J., Zou, J.Y., Kjeldgaard, M. & Jones, T.A. Around O. Int. Tables Crystallogr. F, 353-356 (2001).
-
(2001)
Int. Tables Crystallogr.
, vol.F
, pp. 353-356
-
-
Kleywegt, G.J.1
Zou, J.Y.2
Kjeldgaard, M.3
Jones, T.A.4
Around, O.5
-
45
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
-
Kraulis, P.J. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24, 946-950 (1991).
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
46
-
-
0030815133
-
Raster3D: Photorealistic molecular graphics
-
Merritt, E.A. & Bacon, D.J. Raster3D: photorealistic molecular graphics. Methods Enzymol. 277, 505-524 (1997).
-
(1997)
Methods Enzymol.
, vol.277
, pp. 505-524
-
-
Merritt, E.A.1
Bacon, D.J.2
-
47
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen, C. & Okayama, H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752 (1987).
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
48
-
-
0025944430
-
Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor
-
Clements, J.D. & Westbrook, G.L. Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor. Neuron 7, 605-613 (1991).
-
(1991)
Neuron
, vol.7
, pp. 605-613
-
-
Clements, J.D.1
Westbrook, G.L.2
-
49
-
-
0027081035
-
Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices
-
Colquhoun, D., Jonas, P. & Sakmann, B. Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices. J. Physiol. (Lond.) 458, 261-287 (1992).
-
(1992)
J. Physiol. (Lond.)
, vol.458
, pp. 261-287
-
-
Colquhoun, D.1
Jonas, P.2
Sakmann, B.3
|