Identification of differentially expressed genes in the livers of chronically i-As-treated hamsters

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 713, Issue 1-2, 2011, Pages 48-55

  Hernández, Alba ^a,b   Sampayo Reyes, Adriana ^c   Marcos, Ricard ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Arsenic; Chronic treatment; DD PCR; Gene expression; Genotoxicity; Hamster; Liver; MN RET

Indexed keywords

ARSENIC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOTRANSFORMATION; BODY WEIGHT; CARCINOGENESIS; CELL COMMUNICATION; CELL CYCLE REGULATION; CELL METABOLISM; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FOOD INTAKE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENOTOXICITY; LIVER; LONG TERM EXPOSURE; METHYLATION; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRESS; TELOMERE; UPREGULATION;

ANIMALS; ARSENIC; BODY WEIGHT; CARCINOGENS; CRICETINAE; DRINKING; DRUG-INDUCED LIVER INJURY; EATING; GENE EXPRESSION PROFILING; LIVER; MESOCRICETUS; MUTAGENS;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 79960227048     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2011.05.013     Document Type: Article

References (63)

1. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Some drinking-water disinfectants and contaminants, including arsenic. IARC Monogr. Eval. Carcinog. Risks Hum. 2004, 84:1-477.
2. Rahman M.M., Ng J.C., Naidu R. Chronic exposure of arsenic via drinking water and its adverse health impacts on humans. Environ. Geochem. Health 2009, 31(Suppl. 1):189-200.
3. Navas-Acien A., Silbergeld E.K., Streeter R.A., Clark J.M., Burke T.A., Guallar E. Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidence. Environ. Health Perspect. 2006, 114:641-648.
4. Liu J., Waalkes M.P. Liver is a target of arsenic carcinogenesis. Toxicol. Sci. 2008, 105:24-32.
5. Kitchin K.T. Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites. Toxicol. Appl. Pharmacol. 2001, 172:249-261.
6. Vahter M. Mechanisms of arsenic biotransformation. Toxicology 2002, 181-182:211-217.
7. Styblo M., Del Razo L.M., Vega L., Germolec D.R., LeCluyse E.L., Hamilton G.A., Reed W., Wang C., Cullen W.R., Thomas D.J. Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells. Arch. Toxicol. 2000, 74:289-299.
8. Petrick J.S., Jagadish B., Mash E.A., Aposhian H.V. Monomethylarsonous acid (MMA super(III)) and arsenite: LD sub(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem. Res. Toxicol. 2001, 14:651-656.
9. Aposhian H.V., Aposhian M.M. Arsenic toxicology: five questions. Chem. Res. Toxicol. 2006, 19:1-15.
10. Naranmandura H., Suzuki N., Iwata K., Hirano S., Suzuki K.T. Arsenic metabolism and thioarsenicals in hamsters and rats. Chem. Res. Toxicol. 2007, 20:616-624.
11. Naranmandura H., Suzuki K.T. Formation of dimethylthioarsenicals in red blood cells. Toxicol. Appl. Pharmacol. 2008, 227:390-399.
12. Hirata M., Tanaka A., Hisanaga A., Ishinishi N. Effects of glutathione depletion on the acute nephrotoxic potential of arsenite and on arsenic metabolism in hamsters. Toxicol. Appl. Pharmacol. 1990, 106:469-481.
13. Unis D., Osborne C., Diawara M.M. Arsenite exposure compromises early embryonic development in the golden hamster. Reprod. Toxicol. 2009, 28:329-334.
14. Liang P. From differential display to DNA microarrays-a personal account. J. Cell. Physiol. 2006, 209:653-658.
15. Decordier I., Kirsch-Volders M. The in vitro micronucleus test: from past to future. Mutat. Res. 2006, 607:2-4.
16. Bonassi S., Znaor A., Ceppi M., Lando C., Chang W.P., Holland N., Kirsch-Volders M., Zeiger E., Ban S., Barale R., Bigatti M.P., Bolognesi C., Cebulska-Wasilewska A., Fabianova E., Fucic A., Hagmar L., Joksic G., Martelli A., Migliore L., Mirkova E., Scarfi M.R., Zijno A., Norppa H., Fenech M. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 2007, 28:625-631.
17. Hayashi M., Morita T., Kodama Y., Sofuni T., Ishidate M. The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides. Mutat. Res. 1990, 245:245-249.
18. Liang P., Pardee A.B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 1992, 257:967-971.
19. Chowdhury U.K., Aposhian H.V. Protein expression in the livers and urinary bladders of hamsters exposed to sodium arsenite. Ann. N. Y. Acad. Sci. 2008, 1140:325-334.
20. Kitchin K.T., Ahmad S. Oxidative stress as a possible mode of action for arsenic carcinogenesis. Toxicol. Lett. 2003, 137:3-13.
21. Tapio S., Grosche B. Arsenic in the aetiology of cancer. Mutat. Res. 2006, 612:215-246.
22. Nordenson I., Beckman L. Is the genotoxic effect of arsenic mediated by oxygen free radicalsž. Hum. Hered. 1991, 41:71-73.
23. Shi H., Shi X., Liu K.J. Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol. Cell. Biochem. 2004, 255:67-78.
24. Pi J., Yamauchi H., Kumagai Y., Sun G., Yoshida T., Aikawa H., Hopenhayn-Rich C., Shimojo N. Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water. Environ. Health Perspect. 2002, 110:331-336.
25. Kinoshita A., Wanibuchi H., Morimura K., Wei M., Nakae D., Arai T., Minowa O., Noda T., Nishimura S., Fukushima S. Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice. Cancer Sci. 2007, 98:803-814.
26. Xie Y., Trouba K.J., Liu J., Waalkes M.P., Germolec D.R. Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-ha-ras transgenic (tg.AC) mice. Environ. Health Perspect. 2004, 112:1255-1263.
27. Liu J., Xie Y., Ducharme D.M., Shen J., Diwan B.A., Merrick B.A., Grissom S.F., Tucker C.J., Paules R.S., Tennant R., Waalkes M.P. Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposure. Environ. Health Perspect. 2006, 114:404-411.
28. Miyai K., Richardson A.L., Mayr W., Javitt N.B. Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. 1. Effects of lithocholic, 3beta-hydroxy-5-cholenoic, cholic, and dehydrocholic acids. Lab. Invest. 1977, 36:249-258.
29. Shoda J., Tanaka N., Osuga T., Matsuura K., Miyazaki H. Altered bile acid metabolism in liver disease: concurrent occurrence of C-1 and C-6 hydroxylated bile acid metabolites and their preferential excretion into urine. J. Lipid Res. 1990, 31:249-259.
30. Makishima M., Lu T.T., Xie W., Whitfield G.K., Domoto H., Evans R.M., Haussler M.R., Mangelsdorf D.J. Vitamin D receptor as an intestinal bile acid sensor. Science 2002, 296:1313-1316.
31. Liu J., Benbrahim-Tallaa L., Qian X., Yu L., Xie Y., Boos J., Qu W., Waalkes M.P. Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells. Toxicol. Appl. Pharmacol. 2006, 216:407-415.
32. Germolec D.R., Spalding J., Yu H.S., Chen G.S., Simeonova P.P., Humble M.C., Bruccoleri A., Boorman G.A., Foley J.F., Yoshida T., Luster M.I. Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors. Am. J. Pathol. 1998, 153:1775-1785.
33. Kozul C.D., Hampton T.H., Davey J.C., Gosse J.A., Nomikos A.P., Eisenhauer P.L., Weiss D.J., Thorpe J.E., Ihnat M.A., Hamilton J.W. Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environ. Health Perspect. 2009, 117:1108-1115.
34. Valenzuela O.L., Germolec D.R., Borja-Aburto V.H., Contreras-Ruiz J., Garcia-Vargas G.G., Del Razo L.M. Chronic arsenic exposure increases TGFalpha concentration in bladder urothelial cells of Mexican populations environmentally exposed to inorganic arsenic. Toxicol. Appl. Pharmacol. 2007, 222:264-270.
35. Fry R.C., Navasumrit P., Valiathan C., Svensson J.P., Hogan B.J., Luo M., Bhattacharya S., Kandjanapa K., Soontararuks S., Nookabkaew S., Mahidol C., Ruchirawat M., Samson L.D. Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. PLoS Genet. 2007, 3:e207.
36. Kumagai Y., Sumi D. Arsenic: signal transduction, transcription factor, and biotransformation involved in cellular response and toxicity. Annu. Rev. Pharmacol. Toxicol. 2007, 47:243-262.
37. Muller A.J., Sharma M.D., Chandler P.R., Duhadaway J.B., Everhart M.E., Johnson 3rd B.A., Kahler D.J., Pihkala J., Soler A.P., Munn D.H., Prendergast G.C., Mellor A.L. Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:17073-17078.
38. Pan K., Wang H., Chen M.S., Zhang H.K., Weng D.S., Zhou J., Huang W., Li J.J., Song H.F., Xia J.C. Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma. J. Cancer Res. Clin. Oncol. 2008, 134:1247-1253.
39. Yang G., Xu Y., Chen X., Hu G. IFITM1 plays an essential role in the antiproliferative action of interferon-gamma. Oncogene 2007, 26:594-603.
40. Akyerli C.B., Beksac M., Holko M., Frevel M., Dalva K., Ozbek U., Soydan E., Ozcan M., Ozet G., Ilhan O., Gurman G., Akan H., Williams B.R., Ozcelik T. Expression of IFITM1 in chronic myeloid leukemia patients. Leuk. Res. 2005, 29:283-286.
41. Vahter M.E. Interactions between arsenic-induced toxicity and nutrition in early life. J. Nutr. 2007, 137:2798-2804.
42. Waalkes M.P., Liu J. Early-life arsenic exposure: methylation capacity and beyond. Environ. Health Perspect. 2008, 116:A104.
43. Drobna Z., Walton F.S., Paul D.S., Xing W., Thomas D.J., Styblo M. Metabolism of arsenic in human liver: the role of membrane transporters. Arch. Toxicol. 2010, 84:3-16.
44. Waalkes M.P., Diwan B.A., Rehm S., Ward J.M., Moussa M., Cherian M.G., Goyer R.A. Down-regulation of metallothionein expression in human and murine hepatocellular tumors: association with the tumor-necrotizing and antineoplastic effects of cadmium in mice. J. Pharmacol. Exp. Ther. 1996, 277:1026-1033.
45. Majumder S., Ghoshal K., Gronostajski R.M., Jacob S.T. Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I. Gene Expr. 2001, 9:203-215.
46. Jacob S.T., Majumder S., Ghoshal K. Suppression of metallothionein-I/II expression and its probable molecular mechanisms. Environ. Health Perspect. 2002, 110(Suppl. 5):827-830.
47. Straub A.C., Stolz D.B., Ross M.A., Hernandez-Zavala A., Soucy N.V., Klei L.R., Barchowsky A. Arsenic stimulates sinusoidal endothelial cell capillarization and vessel remodeling in mouse liver. Hepatology 2007, 45:205-212.
48. Straub A.C., Stolz D.B., Vin H., Ross M.A., Soucy N.V., Klei L.R., Barchowsky A. Low level arsenic promotes progressive inflammatory angiogenesis and liver blood vessel remodeling in mice. Toxicol. Appl. Pharmacol. 2007, 222:327-336.
49. Kammerer S., Roth R.B., Hoyal C.R., Reneland R., Marnellos G., Kiechle M., Schwarz-Boeger U., Griffiths L.R., Ebner F., Rehbock J., Cantor C.R., Nelson M.R., Braun A. Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:2004-2009.
50. Sun Q.Y., Schatten H. Role of NuMA in vertebrate cells: review of an intriguing multifunctional protein. Front. Biosci. 2006, 11:1137-1146.
51. Munirajan A.K., Ando K., Mukai A., Takahashi M., Suenaga Y., Ohira M., Koda T., Hirota T., Ozaki T., Nakagawara A. KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death. J. Biol. Chem. 2008, 283:24426-24434.
52. Bioulac-Sage P., Laumonier H., Laurent C., Zucman-Rossi J., Balabaud C. Hepatocellular adenoma: what is new in 2008. Hepatol. Int. 2008, 2:316-321.
53. Yu H.T., Yu M., Li C.Y., Zhan Y.Q., Xu W.X., Li Y.H., Li W., Wang Z.D., Ge C.H., Yang X.M. Specific expression and regulation of hepassocin in the liver and down-regulation of the correlation of HNF1alpha with decreased levels of hepassocin in human hepatocellular carcinoma. J. Biol. Chem. 2009, 284:13335-13347.
54. Servitja J.M., Pignatelli M., Maestro M.A., Cardalda C., Boj S.F., Lozano J., Blanco E., Lafuente A., McCarthy M.I., Sumoy L., Guigo R., Ferrer J. Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver. Mol. Cell. Biol. 2009, 29:2945-2959.
55. Diaz-Villasenor A., Burns A.L., Hiriart M., Cebrian M.E., Ostrosky-Wegman P. Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus. Toxicol. Appl. Pharmacol. 2007, 225:123-133.
56. Yang W.S., Lee W.J., Huang K.C., Lee K.C., Chao C.L., Chen C.L., Tai T.Y., Chuang L.M. mRNA levels of the insulin-signaling molecule SORBS1 in the adipose depots of nondiabetic women. Obes. Res. 2003, 11:586-590.
57. Zhang D., Liu Z.X., Choi C.S., Tian L., Kibbey R., Dong J., Cline G.W., Wood P.A., Shulman G.I. Mitochondrial dysfunction due to long-chain acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:17075-17080.
58. Cho C.Y., Koo S.H., Wang Y., Callaway S., Hedrick S., Mak P.A., Orth A.P., Peters E.C., Saez E., Montminy M., Schultz P.G., Chanda S.K. Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metab. 2006, 3:367-378.
59. Liu L., Trimarchi J.R., Navarro P., Blasco M.A., Keefe D.L. Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis. J. Biol. Chem. 2003, 278:31998-32004.
60. Jiao Y., Zhang W., Liu J., Ni W., Xu W., Jin J., Qian W. Telomere attrition and chromosome instability via downregulation of TRF2 contributes to arsenic trioxide-induced apoptosis of human T-cell leukemia cell line molt-4 cells. Cancer Biol. Ther. 2007, 6.
61. 3 in MGC-803 cells. Eur. J. Pharmacol. 2005, 516:1-9.
62. Redon S., Reichenbach P., Lingner J. Protein-RNA and protein-protein interactions mediate association of human EST1A/SMG6 with telomerase. Nucleic Acids Res. 2007, 35:7011-7022.
63. Reichenbach P., Hoss M., Azzalin C.M., Nabholz M., Bucher P., Lingner J. A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. Curr. Biol. 2003, 13:568-574.