KIF1Bβ functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death

Journal of Biological Chemistry

Volumn 283, Issue 36, 2008, Pages 24426-24434

  Munirajan, Arasambattu K ^a,b,c   Ando, Kiyohiro ^a   Mukai, Akira ^a   Takahashi, Masato ^a   Suenaga, Yusuke ^a   Ohira, Miki ^a   Koda, Tadayuki ^b   Hirota, Toru ^d   Ozaki, Toshinori ^a   Nakagawara, Akira ^a  

^a CHIBA CANCER CENTER   (Japan)

^b HISAMITSU PHARMACEUTICAL CO INC   (Japan)

^c Dr ALM Postgraduate Institute of Basic Medical Sciences   (India)

^d CANCER INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLIFICATION; ANIMAL CELL CULTURE; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELLS; CHROMOSOMES; NUCLEIC ACIDS; RNA; TUMORS;

APOPTOTIC CELL DEATHS; CELL CYCLES; CELL LINES; DISTAL REGIONS; HUMAN CANCERS; KINESIN; MUTATION RATES; NEUROBLASTOMA; NEUROBLASTOMAS; NUDE MOUSE; PROMOTER REGIONS; SHORT INTERFERING; SIX GENES; TUMOR FORMATIONS; TUMOR SUPPRESSOR GENES; TUMOR SUPPRESSORS;

GENETIC ENGINEERING;

PROTEIN KIF1B BETA; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; KIF1B PROTEIN, HUMAN; KINESIN; MESSENGER RNA; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEIN P53; RNA; TP53 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CHROMOSOME 1P; CONTROLLED STUDY; GENE AMPLIFICATION; GENE DELETION; GENE FUNCTION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENE OVEREXPRESSION; HAPLOTYPE; HELA CELL; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; KIF1B BETA GENE; MOUSE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; CANCER TRANSPLANTATION; CELL DIVISION; CHROMOSOME 1; CHROMOSOME DELETION; GENETICS; METABOLISM; RNA INTERFERENCE;

MUS MUSCULUS;

ANIMALS; APOPTOSIS; CELL DIVISION; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 1; G2 PHASE; GENE AMPLIFICATION; GENE DELETION; HELA CELLS; HUMANS; KINESIN; LOSS OF HETEROZYGOSITY; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, NEOPLASM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 54049148638     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802316200     Document Type: Article

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