Differential modulation of akt/glycogen synthase kinase-3β pathway regulates apoptotic and cytoprotective signaling responses

Journal of Biological Chemistry

Volumn 283, Issue 22, 2008, Pages 15469-15478

  Nair, Venugopalan D ^a   Olanow, C Warren ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELL DEATH; CELLS; CHEMICAL ACTIVATION; CHEMICAL REACTIONS; ENZYMES; HYDROGEN; HYDROGEN PEROXIDE; MODULATION; NUCLEIC ACIDS; OXIDATIVE STRESS; PHOSPHORYLATION; RNA; SUBSTRATES;

APOPTOSIS; CATENIN; DEPHOSPHORYLATES; DIFFERENTIAL MODULATIONS; DOPAMINE AGONISTS; DOPAMINE NEURONS; GLYCOGEN SYNTHASE KINASES; KNOCK OUTS; PC12 CELLS; PHOSPHOINOSITIDE; PRIMARY CULTURES; PROAPOPTOTIC FACTORS; SIGNALING RESPONSES; SYNTHASE; TRANSCRIPTIONAL ACTIVATORS;

CELL CULTURE;

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ROPINIROLE; SHORT HAIRPIN RNA; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INDOLE DERIVATIVE; OXIDIZING AGENT;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MESENCEPHALON; NERVE CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL STRAIN; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BETA CATENIN; DOPAMINE; DOPAMINE AGONISTS; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HYDROGEN PEROXIDE; INDOLES; NEURONS; OXIDANTS; OXIDATIVE STRESS; PC12 CELLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION;

EID: 47249083512     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707238200     Document Type: Article

References (60)

1. Forno, L. S. (1996) J. Neuropathol. Exp. Neurol. 55, 259-272
2. Moore, D. J., West, A. B., Dawson, V. L., and Dawson, T. M. (2005) Annu. Rev. Neurosci. 28, 57-87
3. Olanow, C. W. (2004) Annu. Rev. Med. 55, 41-60
4. Beal, M. F. (2003) Ann. N. Y. Acad. Sci. 991, 120-131
5. Teismann, P., Vila, M., Choi, D. K., Tieu, K., Wu, D. C., Jackson-Lewis, V., and Przedborski, S. (2003) Ann. N. Y. Acad. Sci. 991, 272-277
6. Schapira, A., Cooper, J., Dexter, D., Clark, J., Jenner, P., and Marsden, C. (1990) J. Neurochem. 54, 823-827
7. Parker, W. D., Jr., Boyson, S. J., and Parks, J. K. (1989) Ann. Neurol. 26, 719-723
8. Keeney, P. M., Xie, J., Capaldi, R. A., and Bennett, J. P., Jr. (2006) J. Neurosci. 26, 5256-5264
9. Olanow, C. W., Obeso, J. A., and Stocchi, F. (2006) Lancet Neurol. 5, 677-687
10. Du, F., Li, R., Huang, Y., Li, X., and Le, W. (2005) Eur. J. Neurosci. 22, 2422-2430
11. Joyce, J. N., Presgraves, S., Renish, L., Borwege, S., Osredkar, T., Hagner, D., Replogle, M., PazSoldan, M., and Millan, M. J. (2003) Exp. Neurol. 184, 393-407
12. Millan, M. J., Di Cara, B., Hill, M., Jackson, M., Joyce, J. N., Brotchie, J., McGuire, S., Crossman, A., Smith, L., Jenner, P., Gobert, A., Peglion, J. L., and Brocco, M. (2004) J. Pharmacol. Exp. Ther. 309, 921-935
13. Presgraves, S. P., Borwege, S., Millan, M. J., and Joyce, J. N. (2004) Exp. Neurol. 190, 157-170
14. Nair, V. D., Olanow, W., and Sealfon, S. C. (2003) Biochem. J. 373, 25-32
15. Nair, V. D., and Sealfon, S. C. (2003) J. Biol. Chem. 278, 47053-47061
16. Whone, A. L., Watts, R. L., Stoessl, A. J., Davis, M., Reske, S., Nahmias, C., Lang, A. E., Rascol, O., Ribeiro, M. J., Remy, P., Poewe, W. H., Hauser, R. A., and Brooks, D. J. (2003) Ann. Neurol. 54, 93-101
17. Brunt, E. R., Brooks, D. J., Korczyn, A. D., Montastruc, J. L., and Stocchi, F. (2002) J. Neural Transm. 109, 489-502
18. Olanow, C. W., Jenner, P., and Brooks, D. (1998) Ann. Neurol. 44, Suppl. 1, 167-174
19. Nair, V. D. (2006) Apoptosis 11, 955-966
20. Nair, V. D., McNaught, K. S., Gonzalez-Maeso, J., Sealfon, S. C., and Olanow, C. W. (2006) J. Biol. Chem. 281, 39550 -39560
21. Nair, V. D., Yuen, T., Olanow, C. W., and Sealfon, S. C. (2004) J. Biol. Chem. 279, 27494-27501
22. Bouvier, M. M., and Mytilineou, C. (1995) J. Neurosci. 75, 7141-7149
23. Yu, J. Y., Taylor, J., DeRuiter, S. L., Vojtek, A. B., and Turner, D. L. (2003) Mol. Ther. 7, 228-236
24. Wei, Y., Renard, C. A., Labalette, C., Wu, Y., Levy, L., Neuveut, C., Prieur, X., Flajolet, M., Prigent, S., and Buendia, M. A. (2003) J. Biol. Chem. 278, 5188-5194
25. Alessi, D. R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P., and Hemmings, B. A. (1996) EMBO J. 15, 6541-6551
26. Datta, K., Franke, T. F., Chan, T. O., Makris, A., Yang, S. I., Kaplan, D. R., Morrison, D. K., Golemis, E. A., and Tsichlis, P. N. (1995) Mol. Cell. Biol. 15, 2304-2310
27. Bellacosa, A., Chan, T. O., Ahmed, N. N., Datta, K., Malstrom, S., Stokoe, D., McCormick, F., Feng, J., and Tsichlis, P. (1998) Oncogene 17, 313-325
28. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
29. del Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., and Nunez, G. (1997) Science 278, 687-689
30. Brazil, D. P., Park, J., and Hemmings, B. A. (2002) Cell 111, 293-303
31. Castelo-Branco, G., Rawal, N., and Arenas, E. (2004) J. Cell Sci. 117, 5731-5737
32. Woodgett, J. R. (2005) Curr. Opin. Cell Biol. 17, 150-157
33. Lee, K. Y., Koh, S. H., Noh, M. Y., Park, K. W., Lee, Y. J., and Kim, S. H. (2007) Brain Res. 1129, 89-99
34. Maurer, U., Charvet, C., Wagman, A. S., Dejardin, E., and Green, D. R. (2006) Mol. Cell 21, 749-760
35. An, J. H., Vranas, K., Lucke, M., Inoue, H., Hisamoto, N., Matsumoto, K., and Blackwell, T. K. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 16275-16280
36. Chalecka-Franaszek, E., and Chuang, D. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 8745-8750
37. Liu, C., Li, Y., Semenov, M., Han, C., Baeg, G. H., Tan, Y., Zhang, Z., Lin, X., and He, X. (2002) Cell 108, 837-847
38. Cohen, P., and Frame, S. (2001) Nat. Rev. Mol. Cell Biol. 2, 769-776
39. Bhat, R. V., Shanley, J., Correll, M. P., Fieles, W. E., Keith, R. A., Scott, C. W., and Lee, C. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11074-11079
40. Feng, J., Tamaskovic, R., Yang, Z., Brazil, D. P., Merlo, A., Hess, D., and Hemmings, B. A. (2004) J. Biol. Chem. 279, 35510-35517
41. Martin, D., Salinas, M., Fujita, N., Tsuruo, T., and Cuadrado, A. (2002) J. Biol. Chem. 277, 42943-42952
42. Shaw, M., Cohen, P., and Alessi, D. R. (1998) Biochem. J. 336, 241-246
43. Chen, G., Bower, K. A., Ma, C., Fang, S., Thiele, C. J., and Luo, J. (2004) FASEB J. 18, 1162-1164
44. Liang, M. H., and Chuang, D. M. (2007) J. Biol. Chem. 282, 3904-3917
45. Li, H. L., Wang, H. H., Liu, S. J., Deng, Y. Q., Zhang, Y. J., Tian, Q., Wang, X. C., Chen, X. Q., Yang, Y., Zhang, J. Y., Wang, Q., Xu, H., Liao, F. F., and Wang, J. Z. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 3591-3596
46. Wang, W., Yang, Y., Ying, C., Li, W., Ruan, H., Zhu, X., You, Y., Han, Y., Chen, R., Wang, Y., and Li, M. (2007) Neuropharmacology 52, 1678-1684
47. Mishra, R., Barthwal, M. K., Sondarva, G., Rana, B., Wong, L., Chatterjee, M., Woodgett, J. R., and Rana, A. (2007) J. Biol. Chem. 282, 30393-30405
48. Wu, Y., Shang, Y., Sun, S., Liang, H., and Liu, R. (2007) Apoptosis 12, 1365-1375
49. Koh, S. H., Kim, S. H., Kwon, H., Kim, J. G., Kim, J. H., Yang, K. H., Kim, J., Kim, S. U., Yu, H. J., Do, B. R., Kim, K. S., and Jung, H. K. (2004) Neurotoxicology 25, 793-802
50. Schafer, M., Goodenough, S., Moosmann, B., and Behl, C. (2004) Brain Res. 1005, 84-89
51. Itoh, K., Ishii, T., Wakabayashi, N., and Yamamoto, M. (1999) Free Radic. Res. 31, 319-324
52. Rushmore, T. H., and Kong, A. N. (2002) Curr. Drug Metab. 3, 481-490
53. Dore, S., Takahashi, M., Ferris, C. D., Zakhary, R., Hester, L. D., Guastella, D., and Snyder, S. H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2445-2450
54. Baranano, D. E., Rao, M., Ferris, C. D., and Snyder, S. H. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16093-16098
55. McMahon, M., Itoh, K., Yamamoto, M., Chanas, S. A., Henderson, C. J., McLellan, L. I., Wolf, C. R., Cavin, C., and Hayes, J. D. (2001) Cancer Res. 61, 3299-3307
56. Kwak, M. K., Itoh, K., Yamamoto, M., Sutter, T. R., and Kensler, T. W. (2001) Mol. Med. 7, 135-145
57. Jain, A. K., and Jaiswal, A. K. (2007) J. Biol. Chem. 282, 16502-16510
58. Salazar, M., Rojo, A. I., Velasco, D., de Sagarra, R. M., and Cuadrado, A. (2006) J. Biol. Chem. 281, 14841-14851
59. Ikeyama, S., Kokkonen, G., Shack, S., Wang, X. T., and Holbrook, N. J. (2002) FASEB J. 16, 114-116
60. Sasaki, C., Hayashi, T., Zhang, W. R., Warita, H., Manabe, Y., Sakai, K., and Abe, K. (2001) Neurol. Res. 23, 588-592