A Role for TCR Affinity in Regulating Naive T Cell Homeostasis

Journal of Immunology

Volumn 172, Issue 1, 2004, Pages 40-44

  Kieper, William C ^a,b   Burghardt, J Theodore ^a   Surh, Charles D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD5 ANTIGEN; CYTOKINE; INTERLEUKIN 7; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL COMPOSITION; CELL SIZE; CELL SURVIVAL; FEMALE; HOMEOSTASIS; LYMPHOCYTOPENIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0346103729     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.1.40     Document Type: Article

References (27)

1. Freitas. A. A., and B. B. Rocha. 1993. Lymphocyte lifespan: homeostasis, selection and competition. Immunol. Today 14:25.
2. Surh, C. D., and J. Sprent. 2000. Homeostatic T Cell Proliferation. How far can T cells be activated to self-ligands? J. Exp. Med. 192:F9.
3. Tanchot, C., M. M. Rosado, F. Agenes, A. A. Freitas, and B. Rocha. 1997. Lymphocyte homeostasis. Semin. Immunol. 9:331.
4. Sprent, J., and C. D. Surh. 2003. Cytokines and T cell homeostasis. Immunol. Lett. 85:145.
5. Jameson, S. C. 2002. Maintaining the norm: T-cell homeostasis. Nat. Rev. Immunol. 2:547.
6. Tanchot, C., F. A. Lemonnier, B. Pérarnau, A. A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276:2057.
7. Murali-Krishna, K., L. L. Lau, S. Sambhara, F. Lemonnier, J. Altman, and R. Ahmed. 1999. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 286:1377.
8. Ernst, B., D.-S. Lee, J. M. Chang, J. Sprent, and C. D. Surh. 1999. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 11:173.
9. + T cells in lymphopenic hosts. Immunity 11:183.
10. Schluns, K. S., W. C. Kieper, S. C. Jameson, and L. Lefrancois. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1:426.
11. Tan, J. T., E. Dudl, E. LeRoy, R. Murray, J. Sprent, K. I. Weinberg, and C. D. Surh. 2001. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc. Natl. Acad. Sci. USA 98:8732.
12. Viret, C., F. S. Wong, and C. A. Janeway, Jr. 1999. Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition. Immunity 10:559.
13. Rocha, B., and H. von Boehmer. 1991. Peripheral selection of the T cell repertoire. Science 251:1225.
14. + T cells. J. Exp. Med. 195:1533.
15. Tarakhovsky, A., S. B. Kanner, J. Hombach, J. A. Ledbetter, W. Muller, N. Killeen, and K. Rajewsky. 1995. A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269:535.
16. Azzam, H. S., A. Grinberg, K. Lui, H. Shen, E. W. Shores, and P. E. Love. 1998. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J. Exp. Med. 188:2301.
17. Smith, K., B. Seddon, M. A. Purbhoo, R. Zamoyska, A. G. Fisher, and M. Merkenschlager. 2001. Sensory adaptation in naive peripheral CD4 T cells. J. Exp. Med. 194:1253.
18. von Boehmer, H., J. Kirberg, and B. Rocha. 1991. An unusual lineage of α/β T cells that contains autoreactive cells. J. Exp. Med. 174:1001.
19. + cells. J. Exp. Med. 195:1523.
20. Dummer, W., B. Ernst, E. LeRoy, D. Lee, and C. Surh. 2001. Autologous regulation of naive T cell homeostasis within the T cell compartment. J. Immunol. 166:2460.
21. Moses, C. T., K. M. Thorstenson, S. C. Jameson, and A. Khoruts. 2003. Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells. Proc. Natl. Acad. Sci. USA 100:1185.
22. Troy, A. E., and H. Shen. 2003. Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition. J. Immunol. 170:672.
23. Kassiotis, G., R. Zamoyska, and B. Stockinger. 2003. Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells. J. Exp. Med. 197:1007.
24. Dummer, W., A. G. Niethammer, R. Baccala, B. R. Lawson, N. Wagner, R. A. Reisfeld, and A. N. Theofilopoulos. 2002. T cell homeostatic proliferation elicits effective antitumor autoimmunity. J. Clin. Invest. 110:185.
25. Dudley, M. E., J. R. Wunderlich, P. F. Robbins, J. C. Yang, P. Hwu, D. J. Schwartzentruber, S. L. Topalian, R. Sherry, N. P. Restifo, A. M. Hubicki, et al. 2002. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298:850.
26. Gleeson, P. A., B. H. Toh, and I. R. van Driel. 1996. Organ-specific autoimmunity induced by lymphopenia. Immunol. Rev. 149:97.
27. Theofilopoulos, A. N., W. Dummer, and D. H. Kono. 2001. T cell homeostasis and systemic autoimmunity. J. Clin. Invest. 108:335.