Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation

Cardiovascular Research

Volumn 91, Issue 2, 2011, Pages 289-299

  Terada, Ryota ^a   Warren, Sonisha ^a   Lu, Jonathan T ^b   Chien, Kenneth R ^c   Wessels, Andy ^d   Kasahara, Hideko ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Conduction; Congenital; Contractility; Genetics; Heart defects

Indexed keywords

CONNEXIN 40; GAP JUNCTION PROTEIN; MYOSIN LIGHT CHAIN KINASE; SARCOLIPIN; TAMOXIFEN; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; FEMALE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MUTATION; HEART ARRHYTHMIA; HEART ATRIUM SEPTUM DEFECT; HEART CONDUCTION; HEART CONTRACTION; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE SEPTUM DEFECT; HISTOPATHOLOGY; HOMOZYGOSITY; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; THREE DIMENSIONAL IMAGING;

ACETYLCHOLINESTERASE; ANALYSIS OF VARIANCE; ANIMALS; ATRIAL SEPTUM; CALCIUM SIGNALING; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HEART; HEART CONDUCTION SYSTEM; HEART DEFECTS, CONGENITAL; HEART RATE; HEART SEPTAL DEFECTS, ATRIAL; HEART VENTRICLES; HOMEODOMAIN PROTEINS; MALE; MICE; MICE, KNOCKOUT; MORPHOGENESIS; MYOCARDIAL CONTRACTION; TAMOXIFEN; TRANSCRIPTION FACTORS;

EID: 79959962188     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr037     Document Type: Article

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