Voltage-gated sodium channels are required for heart development in zebrafish

Circulation Research

Volumn 106, Issue 8, 2010, Pages 1342-1350

  Chopra, Sameer S ^a   Stroud, Dina Myers ^b   Watanabe, Hiroshi ^a   Bennett, Jeffrey S ^b   Burns, C Geoffrey ^c   Wells, K Sam ^a   Yang, Tao ^a   Zhong, Tao P ^a,b   Roden, Dan M ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Heart development; Ion channels; Scn5La; Zebrafish

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; FLECAINIDE; LIDOCAINE; MIBEFRADIL; NISOLDIPINE; SEA ANEMONE TOXIN; SODIUM CHANNEL NAV1.5; TETRODOTOXIN; VERATRIDINE; ANTISENSE OLIGONUCLEOTIDE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; GATA4 PROTEIN, ZEBRAFISH; HAND2 PROTEIN, ZEBRAFISH; MESSENGER RNA; NKX2.5 PROTEIN, ZEBRAFISH; SODIUM CHANNEL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA; VOLTAGE GATED NA+ CHANNEL NA(V)1.5A; VOLTAGE-GATED NA+ CHANNEL NA(V)1.5A; ZEBRAFISH PROTEIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; MALE; MEMBRANE ELECTROPHYSIOLOGY; MESODERM; MORPHOGENESIS; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SODIUM CURRENT; ZEBRA FISH; AGE; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE POTENTIAL; CHO CELL; CONGENITAL HEART MALFORMATION; CRICETULUS; GASTRULATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; GENOTYPE; HAMSTER; HEART; METABOLISM; MOLECULAR GENETICS; PHENOTYPE; PRENATAL DEVELOPMENT; TRANSGENIC ANIMAL;

AGE FACTORS; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CHO CELLS; CRICETINAE; CRICETULUS; GASTRULATION; GATA TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENOTYPE; HEART; HEART DEFECTS, CONGENITAL; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MYOCARDIUM; OLIGONUCLEOTIDES, ANTISENSE; PHENOTYPE; RNA, MESSENGER; SODIUM CHANNELS; TRANSCRIPTION FACTORS; TRANSFECTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 77952476172     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.213132     Document Type: Article

References (30)

1. Yu FH, Catterall WA. Overview of the voltage-gated sodium channel family. Genome Biol. 2003;4:207.
2. Goldin AL. Resurgence of sodium channel research. Annu Rev Physiol. 2001;63:871-894.
3. Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev. 2005;57:397-409.
4. Roden DM, Balser JR, George AL Jr, Anderson ME. Cardiac ion channels. Annu Rev Physiol. 2002;64:431-475.
5. George AL Jr. Inherited disorders of voltage-gated sodium channels. J Clin Invest. 2005;115:1990-1999.
6. Koopmann TT, Bezzina CR, Wilde AA. Voltage-gated sodium channels: action players with many faces. Ann Med. 2006;38:472-482.
7. Papadatos GA, Wallerstein PM, Head CE, Ratcliff R, Brady PA, Benndorf K, Saumarez RC, Trezise AE, Huang CL, Vandenberg JI, Colledge WH, Grace AA. Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A. 2002;99:6210-6215.
8. Keegan BR, Meyer D, Yelon D. Organization of cardiac chamber progenitors in the zebrafish blastula. Development. 2004;131:3081-3091.
9. Glickman NS, Yelon D. Cardiac development in zebrafish: coordination of form and function. Semin Cell Dev Biol. 2002;13:507-513.
10. Stainier DY. Zebrafish genetics and vertebrate heart formation. Nat Rev Genet. 2001;2:39-48.
11. Novak AE, Jost MC, Lu Y, Taylor AD, Zakon HH, Ribera AB. Gene duplications and evolution of vertebrate voltage-gated sodium channels. J Mol Evol. 2006;63:208-221.
12. Burns CG, Milan DJ, Grande EJ, Rottbauer W, Macrae CA, Fishman MC. High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat Chem Biol. 2005;1:263-264.
13. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. PLoS Genet. 2007;3: e78.
14. Schoenebeck JJ, Keegan BR, Yelon D. Vessel and blood specification override cardiac potential in anterior mesoderm. Dev Cell. 2007;13:254-267.
15. Reiter JF, Alexander J, Rodaway A, Yelon D, Patient R, Holder N, Stainier DY. Gata5 is required for the development of the heart and endoderm in zebrafish. Genes Dev. 1999;13:2983-2995.
16. Sperelakis N, Pappano AJ. Physiology and pharmacology of developing heart cells. Pharmacol Ther. 1983;22:1-39.
17. Davies MP, An RH, Doevendans P, Kubalak S, Chien KR, Kass RS. Developmental changes in ionic channel activity in the embryonic murine heart. Circ Res. 1996;78:15-25.
18. Renaud JF, Romey G, Lombet A, Lazdunski M. Differentiation of the fast Na+ channel in embryonic heart cells: interaction of the channel with neurotoxins. Proc Natl Acad Sci USA. 1981;78:5348-5352.
19. Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DY. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet. 2002;31:106-110.
20. Olson EN. Gene regulatory networks in the evolution and development of the heart. Science. 2006;313:1922-1927.
21. Srivastava D. Making or breaking the heart: from lineage determination to morphogenesis. Cell. 2006;126:1037-1048.
22. Reiter JF, Verkade H, Stainier DY. Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. Dev Biol. 2001;234:330-338.
23. Reifers F, Walsh EC, Leger S, Stainier DY, Brand M. Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar). Development. 2000;127:225-235.
24. Holtzinger A, Evans T. Gata4 regulates the formation of multiple organs. Development. 2005;132:4005-4014.
25. Yelon D, Ticho B, Halpern ME, Ruvinsky I, Ho RK, Silver LM, Stainier DY. The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development. 2000;127:2573-2582.
26. Isom LL. The role of sodium channels in cell adhesion. Front Biosci. 2002;7:12-23.
27. Abriel H, Kass RS. Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins. Trends Cardiovasc Med. 2005;15:35-40. (Pubitemid 40417543)
28. Meadows LS, Isom LL. Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes. Cardiovasc Res. 2005;67:448-458.
29. Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R. The C terminus of the L-type voltage-gated calcium channel Ca (V) 1.2 encodes a transcription factor. Cell. 2006;127:591-606.
30. Rottbauer W, Baker K, Wo ZG, Mohideen MA, Cantiello HF, Fishman MC. Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit Dev Cell. 2001;1:265-275.