S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism

Cell Death and Disease

Volumn 2, Issue 2, 2011, Pages

  Kumar, A ^a   Oskouian, B ^a   Fyrst, H ^a   Zhang, M ^a   Paris, F ^b   Saba, J D ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b INSERM   (France)

Author keywords

Cell cycle arrest; DNA damage; Radiation; S1P lyase; Sphingomyelinase; Sphingosine 1 phosphate

Indexed keywords

CERAMIDE; SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; DRUG DERIVATIVE; LYASE; LYSOPHOSPHOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE LYASE (ALDOLASE); SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE 1-PHOSPHATE LYASE (ALDOLASE);

APOPTOSIS; ARTICLE; CATALYSIS; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYO; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; RADIOSENSITIVITY; ANIMAL; C57BL MOUSE; CELL CYCLE; CELL STRAIN HEK293; FEMALE; GENETICS; METABOLISM; MOUSE; RADIATION EXPOSURE;

MUS;

ALDEHYDE-LYASES; ANIMALS; CELL CYCLE; DNA DAMAGE; FEMALE; HEK293 CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; RADIATION, IONIZING; SPHINGOLIPIDS; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE;

EID: 79959958500     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.3     Document Type: Article

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