A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons

Experimental Neurology

Volumn 223, Issue 1, 2010, Pages 11-18

  Hoffman, Paul N ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Axon regeneration; Axonal transport; Conditioning lesion; Dorsal root ganglion neuron; Gene expression; Intrinsic growth state; Neurofilament protein; Peripheral nerve graft; Retinal ganglion cell neuron; Slow component a (SCa); Slow component b (SCb); Tubulin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ARGINASE 1; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROMODULIN; NEUROTROPHIN; ORNITHINE DECARBOXYLASE; PROTEIN C JUN; TRANSCRIPTION FACTOR SOX11;

CENTRAL NERVOUS SYSTEM; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; MICROTUBULE ASSEMBLY; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE FIBER TRANSPORT; NEUROFILAMENT; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SENSORY NERVE CELL; SPINAL CORD; SPINAL GANGLION;

ANIMALS; AXONAL TRANSPORT; AXONS; CYCLIC AMP; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; NEURONS; PERIPHERAL NERVOUS SYSTEM DISEASES; TUBULIN;

EID: 77950859906     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.09.006     Document Type: Review

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